Wall Teichoic Acid (WTA)
Wall teichoic acid variation in Staphylococcus aureus
... aureus strains frequently exchange genetic material via phage-mediated horizontal gene transfer events, but, in turn, are vulnerable in particular to lytic phages. Here, a novel strategy of S. aureus is described, which ...
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Wall Teichoic Acid Glycosylation Governs Staphylococcus aureus Nasal Colonization
... community-acquired infections. A key factor required for nasal colonization is a cell surface-exposed zwitterionic glycopolymer, termed wall teichoic acid (WTA). However, the precise mechanisms that ...
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Taming wall teichoic acid multi drug resistance in gram positive pathogens
... Wall teichoic acid (WTA) plays important roles in cell growth, division, morphology and as a virulence ...the teichoic acids on to the membrane ...
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Langerhans Cells Sense Staphylococcus aureus Wall Teichoic Acid through Langerin To Induce Inflammatory Responses
... Human, but not mouse, langerin interacts with S. aureus through the conserved  -N- acetylglucosamine (GlcNAc) modifications on wall teichoic acid (WTA), thereby dis- criminating S. aureus from other ...
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Biosynthesis of the Unique Wall Teichoic Acid of Staphylococcus aureus Lineage ST395
... Unique Wall Teichoic Acid of Staphylococcus aureus Lineage ST395 Volker Winstel, a,b Patricia Sanchez-Carballo, c Otto Holst, c Guoqing Xia, a,b,d Andreas Peschel a,b Cellular and Molecular ...
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Activation of the PhoPR mediated response to phosphate limitation is regulated by wall teichoic acid metabolism in Bacillus subtilis
... Metabolism in Bacillus subtilis Kevin M. Devine* Smurfit Institute of Genetics, Trinity College Dublin, Dublin, Ireland Phosphorous is essential for cell viability. To ensure an adequate supply under phosphate limiting ...
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Cell wall architecture and the role of wall teichoic acid in Staphylococcus aureus
... The binding pattern to ConA of both surface proteins and WTA was analysed. A hazy punctate pattern was seen with the binding of WTA, this pattern was seen across all conditions where only WTA was present on the cell ...
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Lactobacillus plantarum possesses the capability for wall teichoic acid backbone alditol switching
... A comparative in silico analysis of the poly(Gro-P) and poly(Rbo-P) associated WTA genes in the B. subtilis strains W23 and 168, respectively, suggests that at least some of the genes encoding poly(Gro-P) synthesis in ...
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Analysis of Staphylococcus aureus wall teichoic acid glycoepitopes by Fourier Transform Infrared Spectroscopy provides novel insights into the staphylococcal glycocode
... The clustering of the glycosyltransferase ∆tarM and ∆tarS mutant as well as double ∆tarM∆tarS mutant strains showed the high sensitivity of FTIR spectroscopy to specifically detect α- and β-GlcNAc substitutes of WTA in ...
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Disruption of d-alanyl esterification of Staphylococcus aureus cell wall teichoic acid by the beta-lactam resistance modifier (-)-epicatechin gallate
... of teichoic acids that are properly D ...cell wall through modulation of divalent cation binding to tei- choic ...Further, teichoic acids may affect the phase tran- sition profile of phospholipid ...
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A New Family of Capsule Polymerases Generates Teichoic Acid Like Capsule Polymers in Gram Negative Pathogens
... as teichoic acid-like polymers due to their similarity to WTA type II (48, 50), a common polymer of the cell envelope of Gram-positive ...modify wall teichoic acid type I, ...
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The Staphylococcus aureus Methicillin Resistance Factor FmtA Is a d Amino Esterase That Acts on Teichoic Acids
... IMPORTANCE Teichoic acids are involved in cell division, cell wall synthesis, biofilm formation, attachment of bacteria to artifi- cial surfaces, and ...of teichoic acids is not fully ...of ...
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Streamlined Synthesis and Evaluation of Teichoic Acid Fragments
... The arrays have shown that very selective antibodies can be generated to recognize specific and well-defined TA epitopes, with minimal binding to the common glycerol phos- phate backbone[r] ...
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Antibody response to teichoic acid and peptidoglycan in Staphylococcus aureus osteomyelitis
... Comparison of a new enzyme-linked immunosorbent assay method with counterimmunoelectrophoresis for detection of teichoic acid antibodies in sera from patients with Staphylococ- cus aureu[r] ...
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Detection of antibody to Staphylococcus aureus teichoic acid by enzyme linked immunosorbent assay
... The opti- mal concentration of antigen for the detection of teichoic acid antibody was determined by mea- suring the amount of antibody, from a known positive serum diluted 1:400, bound [r] ...
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Synthetic Teichoic Acid Conjugate Vaccine against Nosocomial Gram-Positive Bacteria
... In summary, the data presented here describe the potential use of a synthetic polyphosphoglycerol conjugate as vaccine candidate in enterococci. To this end we have used a potent glycerol phosphate hexamer, WH7, selected ...
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Enzyme linked immunosorbent assay for antibodies against teichoic acid in patients with staphylococcal infections
... Symbols: 0, titers above age-correlated upper normal values (positive); 0, titers below age-correlated upper normal values (negative); solid line joins serum samples from same patient. t[r] ...
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Teichoic Acids: Synthesis and Applications
... the acid labile dimethoxytrityl group for temporary protection, the group of Seeberger reported an enol ether based assembly strategy as shown in Scheme ...
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Antibodies to staphylococcal peptidoglycan and its peptide epitopes, teichoic acid, and lipoteichoic acid in sera from blood donors and patients with staphylococcal infections
... Antibodies to the staphylococcal antigens peptidoglycan, P-ribitol teichoic acid, and lipoteichoic acid, as well as to the peptidoglycan epitopes L-Lys-D-Ala-D-Ala, L-Lys-D-Ala, and pent[r] ...
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Theoretical evaluation of wall teichoic acids in the cavitation mediated pores formation in Gram positive bacteria subjected to an electric field
... the wall and that the repulsive electric pressure allows the nucleation to diverge in ...the wall, a pore can ...bacterial wall (~10 – 100 ...the wall we have considered raises question with ...
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