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White matter damage

Thalamic inflammation after brain trauma is associated with thalamo-cortical white matter damage

Thalamic inflammation after brain trauma is associated with thalamo-cortical white matter damage

... tract damage. Other diseases involving white matter damage, including multiple sclerosis and peripheral nerve injury [5] and another study of TBI [22], also show thalamic inflammation, ...

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Inhibition of NADPH oxidase activation reduces EAE-induced white matter damage in mice

Inhibition of NADPH oxidase activation reduces EAE-induced white matter damage in mice

... assembly of the NADPH oxidase complex or knocking down p47 phox reduced ROS production and attenuated neuroinflammation using isolated myelin and primary microglia culture [49]. However, no studies have previ- ously been ...

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White matter damage in maintenance hemodialysis patients: a diffusion tensor imaging study

White matter damage in maintenance hemodialysis patients: a diffusion tensor imaging study

... of white matter ...in white matter ...of white matter damage, which showed improvement after transplantation ...of white matter damage appears most ...

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Clusterin/Apolipoprotein J immunoreactivity is associated with white matter damage in cerebral small vessel diseases

Clusterin/Apolipoprotein J immunoreactivity is associated with white matter damage in cerebral small vessel diseases

... with white matter pathology severity ...axon damage markers such as non-phosphorylated neurofilament H and the amyloid precursor ...with white matter damage in addition to its ...

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Original Article RhEPO protects against white matter damage in neonatal rats by increasing MOG expression

Original Article RhEPO protects against white matter damage in neonatal rats by increasing MOG expression

... by white matter damage, which also exhibited a decrease in the mRNA levels MOG and an increase in the protein levels of EPOR in brain tissues, especially on postnatal days 3 and ...against ...

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Impact of Focal White Matter Damage on Localized Subcortical Gray Matter Atrophy in Multiple Sclerosis: A 5 Year Study

Impact of Focal White Matter Damage on Localized Subcortical Gray Matter Atrophy in Multiple Sclerosis: A 5 Year Study

... WM damage and connected SGM volume was substantially blunted: A significant relationship remained for only 3 of 14 regions (left caudate, right amygdala, and left accumbens), and the additional variance explained ...

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Maternal Receipt of Magnesium Sulfate Does Not Seem to Reduce the Risk of Neonatal White Matter Damage

Maternal Receipt of Magnesium Sulfate Does Not Seem to Reduce the Risk of Neonatal White Matter Damage

... Results. Of the 1518 infants for whom we knew whether the mothers received magnesium sulfate, the first protocol cranial ultrasound scan was available for 1409 infants, the second for 1274 infants, and the third for 1050 ...

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White Matter Damage in Asymptomatic Patients with Sickle Cell Anemia: Screening with Diffusion Tensor Imaging

White Matter Damage in Asymptomatic Patients with Sickle Cell Anemia: Screening with Diffusion Tensor Imaging

... The study was institutional review board–approved and included both prospective and retrospectively acquired data. For the prospec- tive study, the SCA-NL subjects had the homozygous form of SCA, no history of stroke, ...

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Analysis of correlation between cerebral perfusion and KIM score of white matter lesions in patients with Alzheimer’s disease

<p>Analysis of correlation between cerebral perfusion and KIM score of white matter lesions in patients with Alzheimer&rsquo;s disease</p>

... the white matter fi bers at different regions are involved in the composition of cerebral asso- ciation fi bers (callosum), junction fi bers (arcuate fi ber, uncinate fasciculus, cingulum fasciculus, ...a ...

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The Role of MR Imaging in Assessment of Brain Damage from Carbon Monoxide Poisoning: A Review of the Literature

The Role of MR Imaging in Assessment of Brain Damage from Carbon Monoxide Poisoning: A Review of the Literature

... brain damage after carbon monoxide ...gray matter structures such as the globus pallidus and in various regions of cerebral white ...cerebral white matter areas that are more frequently ...

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Diffusion tensor imaging differences relate to memory deficits in diffuse traumatic brain injury

Diffusion tensor imaging differences relate to memory deficits in diffuse traumatic brain injury

... The advantages of DTI have resulted in a growing body of scientific evidence regarding the relationship between white matter damage and neuropsychological deficits in TBI. Studies conducted with ...

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Magnetic Resonance Imaging of Radiation Injury to the Brain

Magnetic Resonance Imaging of Radiation Injury to the Brain

... A characteristic scalloped appearance at the junction of the gray-white matter was seen on MR images of seven patients, and represented extensive white-matter damage involving the more p[r] ...

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Depression in small-vessel disease relates to white matter ultrastructural damage, not disability

Depression in small-vessel disease relates to white matter ultrastructural damage, not disability

... Study 2: Extended model incorporating DTI data. In the subgroup of participants with SVD who underwent DTI MRI, we added median FA (a measure of global white matter damage), global cognitive deficit, ...

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White matter changes in Alzheimer’s disease: a focus on myelin and oligodendrocytes

White matter changes in Alzheimer’s disease: a focus on myelin and oligodendrocytes

... of white matter damage should be emphasized. White matter hyperintensities tend to be distributed in brain areas with relatively low perfusion levels, particularly in the deep, ...

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Relationship of acute axonal damage, Wallerian degeneration, and clinical disability in multiple sclerosis

Relationship of acute axonal damage, Wallerian degeneration, and clinical disability in multiple sclerosis

... axonal damage and loss, IHC for the early macrophage ac- tivation antigen S100A9 was performed, and all animals were found to have active lesions with recent monocyte invasion ...demyelinated white ...

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Production of IL-16 correlates with CD4+ Th1 inflammation and phosphorylation of axonal cytoskeleton in multiple sclerosis lesions

Production of IL-16 correlates with CD4+ Th1 inflammation and phosphorylation of axonal cytoskeleton in multiple sclerosis lesions

... cord white matter ...cord white matter ...normal-appearing white matter (NAWM) adjacent to acute lesions, pro-IL-16 levels were approximately one third those of acute lesions, ...

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White matter development in early puberty: a longitudinal volumetric and diffusion tensor imaging twin study.

White matter development in early puberty: a longitudinal volumetric and diffusion tensor imaging twin study.

... White matter volume in 8 and 9 year old children is highly heritable ...that white matter surface area is also strongly influenced by ...in white matter microstructure during ...

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Actualities on molecular pathogenesis and repairing processes of cerebral damage in perinatal hypoxic-ischemic encephalopathy

Actualities on molecular pathogenesis and repairing processes of cerebral damage in perinatal hypoxic-ischemic encephalopathy

... As white matter contains both oligodendroglial and axo- nal components it is still not clear whether, in diffuse PVL, H-I injuries involve only the oligodendrocytes or also the ...axonal damage has ...

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Diffuse Tract Damage in the Hemispheric Deep White Matter May Correlate with Global Cognitive Impairment and Callosal Atrophy in Patients with Extensive Leukoaraiosis

Diffuse Tract Damage in the Hemispheric Deep White Matter May Correlate with Global Cognitive Impairment and Callosal Atrophy in Patients with Extensive Leukoaraiosis

... Several recent DTI studies have suggested that NAWM as well as WMLs show reduced DA, which contributed to global cognitive impairment in the patients with WMLs. 3,7,26 Al- though the histogram approach focusing on NAWM ...

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White matter microstructural damage in early treated phenylketonuric patients

White matter microstructural damage in early treated phenylketonuric patients

... RD and MD values are usually associated to a better WM microstructure [2, 40, 60, 61]. Moreover, re- search shows that in healthy populations MD values decrease with age during childhood (increased myelin- ation) while ...

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