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Why the subthalamic nucleus?

Involvement of the subthalamic nucleus in engagement with behaviourally relevant stimuli

Involvement of the subthalamic nucleus in engagement with behaviourally relevant stimuli

... Abstract In this study we investigate how the basal ganglia (BG) may process the behavioural relevance of environmental cues by recording local field potentials (LFPs) in the subthalamic nucleus of patients ...

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Comparison of oscillatory activity in subthalamic nucleus in Parkinson's disease and dystonia

Comparison of oscillatory activity in subthalamic nucleus in Parkinson's disease and dystonia

... the subthalamic nucleus (STN) has been successfully used to treat both Parkinson’s disease (PD) and ...of subthalamic LFPs differed between dystonia off and PD on/off, and between PD off and on over ...

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Brain networks modulated by subthalamic nucleus deep brain stimulation.

Brain networks modulated by subthalamic nucleus deep brain stimulation.

... the subthalamic nucleus reveals its role in the integration of the emotional and motor aspects of ...for subthalamic deep brain stimulation surgery in Parkinson’s ...

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Brain networks modulated by subthalamic nucleus deep brain stimulation

Brain networks modulated by subthalamic nucleus deep brain stimulation

... Subthalamic nucleus connectivity to limbic cortical areas Comparison of neighbouring contacts revealed a signifi- cantly higher connectivity of ventral STN to limbic targets—medial temporal structures ...

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Subthalamic nucleus stimulation impairs emotional conflict adaptation in
Parkinson’s disease

Subthalamic nucleus stimulation impairs emotional conflict adaptation in Parkinson’s disease

... The subthalamic nucleus (STN) occupies a strategic position in the motor network, slowing down responses in situations with conflicting perceptual ...

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Dopamine dependency of oscillations between subthalamic nucleus and pallidum in Parkinson's disease

Dopamine dependency of oscillations between subthalamic nucleus and pallidum in Parkinson's disease

... The extent of synchronization within and between the nuclei of the basal ganglia is unknown in Parkinson’s disease. The ques- tion is an important one because synchronization will increase postsynaptic efficacy at ...

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Automatic Subthalamic Nucleus Targeting for Deep Brain Stimulation. A Validation Study

Automatic Subthalamic Nucleus Targeting for Deep Brain Stimulation. A Validation Study

... a Ecole Polytechnique F´ ´ ed´ erale de Lausanne (EPFL), Signal Processing Institute, Lausanne, Switzerland b Department of Neurosurgery, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland Abstract In ...

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Role of the Subthalamic Nucleus in the Circuitry Mediating Food- and Cocaine-Seeking Behavior

Role of the Subthalamic Nucleus in the Circuitry Mediating Food- and Cocaine-Seeking Behavior

... The subthalamic nucleus (STN) is part of the basal ganglia, which play a crucial role in motor control and in processing information from motor cortical ...the nucleus accumbens (NAcc), a structure ...

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Does Deep Brain Stimulation of the Subthalamic Nucleus Prolong Survival in Parkinson's Disease?

Does Deep Brain Stimulation of the Subthalamic Nucleus Prolong Survival in Parkinson's Disease?

... AL. Subthalamic nucleus lesion in rats prevents dopaminergic nigral neuron degeneration after striatal 6-OHDA injection: behavioural and immunohistochemical ...the subthalamic nucleus supports ...

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Subthalamic nucleus deep brain stimulation in elderly patients – analysis of outcome and complications

Subthalamic nucleus deep brain stimulation in elderly patients – analysis of outcome and complications

... Methods: Bilateral electrode implantation into the subthalamic nucleus (STN) was performed in a total of 73 patients suffering from Parkinson's disease. Patients were analyzed retrospectively. For this ...

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Oscillatory Activity in the Subthalamic Nucleus and Motor Cortex in a Pharmacological Model of Parkinsonian Tremor

Oscillatory Activity in the Subthalamic Nucleus and Motor Cortex in a Pharmacological Model of Parkinsonian Tremor

... the subthalamic nucleus (Collins-Praino et ...and subthalamic nucleus (STN) of PD patients, and it has been suggested that exclusive synchrony in this frequency range contributes to motor ...

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Human Subthalamic Nucleus in Movement Error Detection and Its Evaluation during Visuomotor Adaptation

Human Subthalamic Nucleus in Movement Error Detection and Its Evaluation during Visuomotor Adaptation

... the subthalamic nucleus (STN) from electrodes implanted in patients with Parkinson’s disease, while they moved a joystick-controlled cursor to visual targets displayed on a computer ...

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Five Year Outcomes of Bilateral Subthalamic Nucleus Stimulation in Japanese Patients with Parkinson’s Disease

Five Year Outcomes of Bilateral Subthalamic Nucleus Stimulation in Japanese Patients with Parkinson’s Disease

... (2008) Long-Term Outcome of 50 Consecutive Parkinson’s Disease Patients Treated with Subthalamic Deep Brain Stimulation. (2009) Bilateral Subthalamic Nucleus Stimulation in Advanced Par[r] ...

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Neuronal Activity in the Human Subthalamic Nucleus Encodes Decision Conflict during Action Selection

Neuronal Activity in the Human Subthalamic Nucleus Encodes Decision Conflict during Action Selection

... The subthalamic nucleus (STN), which receives excitatory inputs from the cortex and has direct connections with the inhibitory pathways of the basal ganglia, is well positioned to efficiently mediate action ...

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Five-year follow-up of bilateral stimulation of the subthalamic nucleus in advanced Parkinson's disease

Five-year follow-up of bilateral stimulation of the subthalamic nucleus in advanced Parkinson's disease

... rioration probably reflect the natural history of long-standing Parkinson’s disease. Psychiatric problems, including depression or mania, have been reported by several groups in pa- tients treated with stimulation of the ...

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Effects of Subthalamic Nucleus Deep Brain Stimulation on the Phonation and Articulation of the Patients with Parkinson's Disease

Effects of Subthalamic Nucleus Deep Brain Stimulation on the Phonation and Articulation of the Patients with Parkinson's Disease

... Department of Neurology, Yongdong Severance Hospital, Seoul, Korea Background: The purpose of this study was to investigate the effects of the subthalamic nucleus (STN) deep brain stimulation (DBS) on the ...

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Deep Brain Stimulation of the Subthalamic Nucleus Improves Lexical Switching
in Parkinsons Disease Patients

Deep Brain Stimulation of the Subthalamic Nucleus Improves Lexical Switching in Parkinsons Disease Patients

... Introduction Reduced performance in verbal fluency (VF) tasks is a robust finding in patients with Parkin- son ’s disease (PD), in particular if treated by Deep Brain Stimulation of the subthalamic nucleus ...

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Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease: The Effect of Varying Stimulation Parameters

Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease: The Effect of Varying Stimulation Parameters

... Abstract. Subthalamic Nucleus Deep Brain Stimulation (STN DBS) is a well-established and effective treatment modality for selected patients with Parkinson’s disease ...

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Factors affecting early decline of executive function after subthalamic nucleus stimulation in Parkinson’s disease

Factors affecting early decline of executive function after subthalamic nucleus stimulation in Parkinson’s disease

... ABSTRACT Subthalamic nucleus deep brain stimulation (STN DBS) is an effective treatment for medically refractory Parkinson’s disease (PD). However, a minority of patients develop cognitive problems, ...

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Reduced GABA Content in the Motor Thalamus during effective deep brain stimulation of the subthalamic nucleus

Reduced GABA Content in the Motor Thalamus during effective deep brain stimulation of the subthalamic nucleus

... the subthalamic nucleus (STN), in Parkinson’s disease (PD) patients, is a well established therapeutic option, but its mechanisms of action are only partially ...

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