wild type
Wild type measles virus attenuation independent of type I IFN
... MV wild-type isolates were available for ...or wild type MVs use CD150 (SLAM) as their main host cell receptor to attach to cells and so are most easily isolated on cell lines expressing this ...
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The Resistant Population Cutoff (RCOFF): a New Concept for Improved Characterization of Antimicrobial Susceptibility Patterns of Non Wild Type Bacterial Populations
... the wild-type popula- tion into different interpretative categories as the wild-type is re- garded to be a genotypic entity despite population-intrinsic (mi- cro-)variations in drug ...
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Effect of Cleavage Mutants on Syncytium Formation Directed by the Wild-Type Fusion Protein of Newcastle Disease Virus
... the wild-type F protein were ...of wild-type and mutant F protein cDNAs resulted in an inhibition of syncytium ...the wild-type ...the wild-type protein formed ...
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Wild-Type Measles Virus with the Hemagglutinin Protein of the Edmonston Vaccine Strain Retains Wild-Type Tropism in Macaques
... Infection of primary cell culture with recombinant MV strains. We first examined the cell specificities of IC323-EGFP and EdH-EGFP in vitro. In B95a cells, both IC323-EGFP and EdH- EGFP induced large syncytia and strong ...
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WILD-TYPE AND MUTANT STOCKS OF MORMONIELLA
... Information about each wild-type stock and mutant stock (other than R mutants) (Table 1) includes the name, stock number, published name, and symbol if any (with[r] ...
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FOLFIRI plus panitumumab in the treatment of wild type KRAS and wild type NRAS metastatic colorectal cancer
... Although the patient groups and chemotherapy reg- imens differed, many studies have shown that patients with mCRC with limited metastases undergoing only liver metastasectomies may exhibit prolonged survival if the ...
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Structural analysis of wild-type and mutant human immunodeficiency virus type 1 Tat proteins.
... These mutants, wild type in structure but reduced in activity, identify residues in the wild-type protein that may directly contact other molecules during Tat function... STRUCTURE OF HI[r] ...
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Haplotypes that are mosaic for wild-type and t complex-specific alleles in wild mice.
... The preponderance of mosaic haplotypes in both groups of mice can be explained by any one of the following hypotheses: genetic recombination between t haplotypes and their w[r] ...
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Effect of simultaneous administration of cold adapted and wild type influenza A viruses on experimental wild type influenza infection in humans
... In subjects given the wt virus alone, peak virus titers were recorded 2 days after infection, while in the group given the mixed inoculum, the peak of virus shedding was delayed until da[r] ...
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Phase I, open-label study of pasireotide in patients with BRAF-wild type and NRAS-wild type, unresectable and/or metastatic melanoma
... The secondary objectives included the assessment of safety at study completion, disease control rate (DCR; defined as the proportion of patients with a best overall response (ORR) of [r] ...
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WILD-TYPE AND MUTANT STOCKS OF ASPERGILLUS NIDULANS
... These stocks are maintained at the Fungal Genetics Stock Center, Dartmouth College, and are available for use in research or teaching. OGATA, 1964 Neurospora stock list, second revi[r] ...
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Original Article Mutation status of ras genes in breast cancers with overexpressed p21Ras protein
... the wild type p21Ras overexpression induce proliferation and malig- nant transformation remains ...that wild type p21Ras can activate JAK2, either alone or together with the Wnt pathway, to ...
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Voltage gated calcium channels of Paramecium cilia
... the wild-type cells into the pwA or pwB cells caused the mutants to regain the voltage-activated calcium conductance without new protein synthesis (Haga et ...
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Genetic and biochemical studies of mitochondria in the yeast saccharomyces cerevisiae
... enzymatic oxidative decarboxylation. Acetolactate is formed by the action of the enzyme acetohydroxy acid synthase encoded by the ILV2 gene. Diacetyl produces an off-flavour in lager and normally an expensive and time ...
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G140S/Q148R and N155H mutations render HIV 2 Integrase resistant to Raltegravir whereas Y143C does not
... Biochemical studies have demonstrated that Q148R, N155H and Y143C are primary resistance mutations giving rise to HIV-1 resistance whereas G140S/A and E92Q are secondary resistance mutations increasing resistance and ...
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Case Report Clear cell sarcoma of soft tissue with multiple cutaneous and subcutaneous metastases resembling plasma cell myeloma: a case study and literature review
... Gene mutations without notable results identified by next-generation sequencing of the patient Gene Type Gene Type ABL1 Wild type KDR VEGFR2 Wild type AKT1 Wild type KRAS Wild type ALK W[r] ...
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Scanning mutagenesis of the I-II loop of the Cav2.2 calcium channel identifies residues Arginine 376 and Valine 416 as molecular determinants of voltage dependent G protein inhibition
... the wild type channels (data not shown); moreover, at the majority of test potentials examined, the mutation yielded no significant changes in the rates of activation and inactivation (versus WT channels, ...
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Enzymatic activity of poliovirus RNA polymerase mutants with single amino acid changes in the conserved YGDD amino acid motif.
... An antipeptide antibody directed against the wild-type core amino acid segment containing the YGDD region of the poliovirus polymerase reacted with the wild-type recombinant RNA polymera[r] ...
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Epstein-Barr virus EBNA3C represses Cp, the major promoter for EBNA expression, but has no effect on the promoter of the cell gene CD21.
... Because aa 346 to 543 are essential for the repression of Cp and encompass the region which, when linked to the GAL4 DBD, represses almost as well as wild-type EBNA3C (4), we suggest that it makes contact ...
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Retrovirus Restriction by TRIM5 Proteins Requires Recognition of Only a Small Fraction of Viral Capsid Subunits
... of wild-type and G89V mutant CA proteins by SRM LC- MS/MS of tryptic ...to wild-type and G89V mutant CA in the mixtures were then quantified by SRM for unique peptides specific to the ...
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