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Wild-type mice

Chikungunya Virus Arthritis in Adult Wild-Type Mice

Chikungunya Virus Arthritis in Adult Wild-Type Mice

... of mice infected with the Reunion Island isolate was significantly higher than that seen for mice infected with the Asian isolate (see ...isolate-inoculated mice, some interstitial inflammatory cells ...

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CD36 involvement in orosensory detection 
of dietary lipids, spontaneous fat 
preference, and digestive secretions

CD36 involvement in orosensory detection of dietary lipids, spontaneous fat preference, and digestive secretions

... and mice exhibit a spontaneous attraction for ...in wild-type and CD36-null mice. In mice, RT-PCR experiments with primers specific for candidate lipid-binding proteins revealed that ...

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Arginase impairs hypoxic pulmonary vasoconstriction in murine endotoxemia

Arginase impairs hypoxic pulmonary vasoconstriction in murine endotoxemia

... from wild-type and NOS2 −/− mice after chal- lenge with either saline or LPS was conducted with “limma” (Linear Models for Microarray and RNA-Seq, ...and wild-type ...in ...

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CMTM2 ) and CMTM2 (heterozygote) and CMTM2 (homozygote) mice to examine the CMTM2 level. The number of litters and

CMTM2 ) and CMTM2 (heterozygote) and CMTM2 (homozygote) mice to examine the CMTM2 level. The number of litters and

... the number of pups were counted and pregnancy rates calculated. The motility and morphology of the sperm and the histology of testes were analyzed. Serum testosterone and FSH concentrations were also measured. Standard ...

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PubMedCentral-PMC4861228.pdf

PubMedCentral-PMC4861228.pdf

... obese mice are more effective at extracting energy from food than those of lean mice, and that this trait can be passed to germ-free (GF) mice via microbial transplantation, causing increased ...GF ...

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Regulatory Role of CD1d in Neurotropic Virus Infection

Regulatory Role of CD1d in Neurotropic Virus Infection

... infected wild-type and CD1 ⫺/⫺ mice with DA virus of the TO subgroup of TMEV and observed the mice for clinical ...both wild-type and CD1 ⫺/⫺ mice ...infected mice ...

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Pathogenesis of Herpes Simplex Virus Type 1-Induced Corneal Inflammation in Perforin-Deficient Mice

Pathogenesis of Herpes Simplex Virus Type 1-Induced Corneal Inflammation in Perforin-Deficient Mice

... HSK. Wild-type (C57BL/6) and perforin-deficient (PKO) mice were infected intracorneally with HSV-1 strain ...PKO mice than in infected wild-type ...infected ...

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Impaired IL 18 processing protects caspase 1–deficient mice from ischemic acute renal failure

Impaired IL 18 processing protects caspase 1–deficient mice from ischemic acute renal failure

... whether mice deficient in the proinflammatory caspase-1, which cleaves precursors of IL-1b and IL-18, were protected against ischemic acute renal failure ...–/– mice developed less ischemic ARF as judged by ...

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Mast cells contribute to double-stranded RNA-induced augmentation of airway eosinophilia in a murine model of asthma

Mast cells contribute to double-stranded RNA-induced augmentation of airway eosinophilia in a murine model of asthma

... produce type-I IFNs and proinflammatory cytokines including IL-6 ...of type-I IFNs ...−/− mice, IPS-1 −/− mice, IRF-3 −/− mice, and wild-type C57BL/6 ...naive mice ...

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Hypoxia induces severe right ventricular dilatation and infarction in heme oxygenase 1 null mice

Hypoxia induces severe right ventricular dilatation and infarction in heme oxygenase 1 null mice

... ) mice and subjected them to hypoxia (10% oxygen) for five to seven ...in wild-type and HO-1 –/– ...in wild-type mice, the increase was greater in HO-1 –/– ...–/– mice. ...

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Analysis of inflammation-related nigral degeneration and locomotor function in
DJ-1
                     −/− mice

Analysis of inflammation-related nigral degeneration and locomotor function in DJ-1 −/− mice

... DJ-1−/− mice following repeated, serial systemic low- dose LPS administration could be attributed to upregulation of anti-oxidant responses as a developmental consequence of DJ-1 ...in wild-type or ...

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Defective CD4+CD25+regulatory T cell functioning in collagen induced arthritis: an important factor in pathogenesis, counter regulated by endogenous IFN γ

Defective CD4+CD25+regulatory T cell functioning in collagen induced arthritis: an important factor in pathogenesis, counter regulated by endogenous IFN γ

... and wild-type mice were sensitised with a single intradermal injection at the base of the tail with 100 µl of the emulsion on day ...immunisation, mice were exam- ined for signs of arthritis ...

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Igf2 Gene Expression Levels in Wild-Type and Mutant Mice

Igf2 Gene Expression Levels in Wild-Type and Mutant Mice

... in wild-type mice during development and is altered in several mutant mice bearing deletions at the Igf2/H19 ...both wild-type and mutant ...all mice analyzed, except in ...

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GW501516-activated PPARβ/δ promotes liver fibrosis via p38-JNK MAPK-induced hepatic stellate cell proliferation

GW501516-activated PPARβ/δ promotes liver fibrosis via p38-JNK MAPK-induced hepatic stellate cell proliferation

... treated wild type and PPARβ/δ-null mice were performed with the mouse cytokine/chemo- kine LINCOplex KIT, 96-well plate assay (LINKO Re- search, MCYTO-70K) on a Luminex R ...oil) wild ...

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Chronic Pseudomonas aeruginosa infection-induced chronic bronchitis and emphysematous changes in CCSP-deficient mice

Chronic <em>Pseudomonas aeruginosa</em> infection-induced chronic bronchitis and emphysematous changes in CCSP-deficient mice

... (CCSP–/–) mice in comparison with wild-type ...CCSP-/- mice and four wild-type mice were ...CCsP-/- mice was significantly elevated in comparison with ...

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Quinine controls body weight gain without affecting food intake in male C57BL6 mice

Quinine controls body weight gain without affecting food intake in male C57BL6 mice

... What is then the Trpm5-dependent mechanism of diminished body weight gain? Trpm5 is expressed in the taste buds [9], gastrointestinal tract [10], pancreas [11] and other hollow organs. In the gastrointestinal tract Trpm5 ...

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Transgenic mice over expressing carbonic anhydrase I showed aggravated joint inflammation and tissue destruction

Transgenic mice over expressing carbonic anhydrase I showed aggravated joint inflammation and tissue destruction

... CA1-Tg mice, the contours of the cartilaginous tissues were diffuse due to chondrophyte ...CA1-Tg mice treated with collagen, the disk space disappeared, and chondrophyte/osteophyte fusion with the ...

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CYP2E1 potentiation of LPS and TNFα-induced hepatotoxicity by mechanisms involving enhanced oxidative and nitrosative stress, activation of MAP kinases, and mitochondrial dysfunction

CYP2E1 potentiation of LPS and TNFα-induced hepatotoxicity by mechanisms involving enhanced oxidative and nitrosative stress, activation of MAP kinases, and mitochondrial dysfunction

... or wild type control SV129 mice were treated with LPS plus ...C57Bl/6 mice, liver injury was observed in the wild type SV129 mice treated with LPS plus pyrazole, but not ...

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Cyclooxygenase-2 expression in oligodendrocytes increases sensitivity to excitotoxic death

Cyclooxygenase-2 expression in oligodendrocytes increases sensitivity to excitotoxic death

... in wild-type and COX-2 knockout mice ...in wild-type ...in mice that lack the microsomal PGE synthase 1 (MPGES-1) gene that codes for the enzyme that synthe- sizes PGE2 from ...

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Side branching and luminal lineage commitment by ID2 in developing mammary glands

Side branching and luminal lineage commitment by ID2 in developing mammary glands

... female mice had normal ductal trees, but showed defects in lobuloalveologenesis during pregnancy (Miyoshi et ...–/– mice during pregnancy might be secondary defects caused by impaired luminal lineage ...

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