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wing imaginal disc

Cap-n-Collar Promotes Tissue Regeneration by Regulating ROS and JNK Signaling in the Drosophila melanogaster Wing Imaginal Disc

Cap-n-Collar Promotes Tissue Regeneration by Regulating ROS and JNK Signaling in the Drosophila melanogaster Wing Imaginal Disc

... The wing imaginal disc of the fruit fly, Drosophila mela- nogaster, is capable of substantial regeneration, enabling us to ask questions about the regulation of regeneration using this genetically ...

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Integrating force sensing and signaling pathways in a model for the regulation of wing imaginal disc size

Integrating force sensing and signaling pathways in a model for the regulation of wing imaginal disc size

... The wing imaginal disc of Drosophila serves as a widely used model system to study this ...the disc during growth. Growth stops once compression levels in the disc center reach a ...

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Essential basal cytonemes take up Hedgehog in the Drosophila wing imaginal disc

Essential basal cytonemes take up Hedgehog in the Drosophila wing imaginal disc

... To determine if cells deficient for Dia or SCAR are competent for Hh signal transduction despite their inability to take up Hh from P compartment Hh-expressing cells, we expressed a membrane- tethered form of Hh (CD2:Hh) ...

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Dynamics of decapentaplegic expression during regeneration 
of the Drosophila melanogaster wing imaginal disc

Dynamics of decapentaplegic expression during regeneration of the Drosophila melanogaster wing imaginal disc

... In order to reveal the specific location of regenerative proliferation, wing imaginal discs from wild type late third instar larvae were dissected, injected into adult hosts and cultivated for four days. ...

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Dual function of the Drosophila Alk1/Alk2 ortholog Saxophone
shapes the Bmp activity gradient in the wing imaginal disc

Dual function of the Drosophila Alk1/Alk2 ortholog Saxophone shapes the Bmp activity gradient in the wing imaginal disc

... the wing pouch respond to graded levels of pMad by activating three Bmp target genes, spalt (sal), optomotor blind (omb) and vestigial (vg), at different distances from the AP boundary (Lecuit et ...adult ...

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Cell dynamics underlying oriented growth of the Drosophila wing imaginal disc

Cell dynamics underlying oriented growth of the Drosophila wing imaginal disc

... Fig. 6. Widespread effects on morphogen signaling and PCP upon perturbation of 20E signaling in vivo. (A-D) A dominant-negative allele of EcR-B1 (W650A, abbreviated EcR-DN) was overexpressed for 24 h in the dorsal ...

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Role of Jun N terminal Kinase (JNK) signaling in the wound healing and regeneration of a Drosophila melanogaster wing imaginal disc

Role of Jun N terminal Kinase (JNK) signaling in the wound healing and regeneration of a Drosophila melanogaster wing imaginal disc

... the disc halts its growth; at 0 h APF most of the cells in the wing blade are arrested in G2 (Milan et ...to wing formation. Conversely, inconsistent with the normal disc development, a ...

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Nab controls the activity of the zinc finger transcription factors
Squeeze and Rotund in Drosophila development

Nab controls the activity of the zinc finger transcription factors Squeeze and Rotund in Drosophila development

... the wing imaginal disc and also for determining specific neuronal fates in the embryonic ...in wing development and is required to limit the expression of wingless (wg) in the wing ...

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Activation and repression activities of ash2 in
Drosophila wing imaginal discs

Activation and repression activities of ash2 in Drosophila wing imaginal discs

... in wing imaginal discs is the response to gradients of the morphogen ...the wing imaginal disc (Podos and Ferguson, 1999; Strigini and Cohen, ...in wing development, such as kni ...

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TIE DYE: a combinatorial marking system to visualize and genetically manipulate clones during development in Drosophila melanogaster

TIE DYE: a combinatorial marking system to visualize and genetically manipulate clones during development in Drosophila melanogaster

... the disc proper (excluding the peripodial epithelium) of the 3rd-instar wing-imaginal ...(non-irradiated) wing imaginal disc is shown in a merged image ...the disc proper ...

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Compartments and the control of growth in the Drosophila wing
imaginal disc

Compartments and the control of growth in the Drosophila wing imaginal disc

... Drosophila wing may be a useful model system with which to analyse growth ...the wing imaginal disc, which initially contains about 40 cells (Lawrence and Morata, 1977) that proliferate during ...

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Actin capping protein α maintains vestigial expressing
cells within the Drosophila wing disc epithelium

Actin capping protein α maintains vestigial expressing cells within the Drosophila wing disc epithelium

... the wing disc, y, w; FRT42D, cpa or tsr/CyO P(y + ) or y, w; FRT40, capt/SM6-TM6B males were crossed to y, w, hsFLP122; FRT42D or 40, ubi-GFP ...collection. Wing discs were dissected from crawling ...

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Cell competition, growth and size control in the Drosophila wing
imaginal disc

Cell competition, growth and size control in the Drosophila wing imaginal disc

... prepupal wing discs and made a careful 3D reconstruction using a deconvolution program (for details see Materials and ...the wing imaginal disc with high accuracy (see ...

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Oncogenic cooperation between Yorkie and the conserved microRNA miR 8 in the wing disc of Drosophila

Oncogenic cooperation between Yorkie and the conserved microRNA miR 8 in the wing disc of Drosophila

... during wing development led us to study the regulation of miR-8 expression in the wing imaginal ...the wing disc, whereas GFP levels are lower in the wing pouch and notum ...

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Apical accumulation of the Drosophila PDGF/VEGF receptor ligands
provides a mechanism for triggering localized actin polymerization

Apical accumulation of the Drosophila PDGF/VEGF receptor ligands provides a mechanism for triggering localized actin polymerization

... the wing imaginal disc, to follow the consequences of uniform PVR ...wild-type disc in A with ...contained wing imaginal discs that were approximately five times larger than ...

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Notch signalling coordinates tissue growth and wing fate specification in
Drosophila

Notch signalling coordinates tissue growth and wing fate specification in Drosophila

... developing wing imaginal disc, expression of the homeodomain protein Homothorax (Hth) and the zinc-finger transcription factor Teashirt (Tsh) was restricted to the presumptive body wall, while the ...

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Caspase inhibition during apoptosis causes abnormal signalling and
developmental aberrations in Drosophila

Caspase inhibition during apoptosis causes abnormal signalling and developmental aberrations in Drosophila

... To characterise the events associated with inducible apoptosis, we chose the wing imaginal disc, which normally has very low endogenous apoptotic levels (Milan et al., 1997). However, these can be ...

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SoxF is part of a novel negative feedback loop in the
wingless pathway that controls proliferation in the
Drosophila wing disc

SoxF is part of a novel negative feedback loop in the wingless pathway that controls proliferation in the Drosophila wing disc

... Wild-type wing imaginal disc of a late L3 Drosophila larva counterstained with the actin marker rhodamine-phalloidin (B is a cross-section of the disc shown in ...the wing pouch ...the ...

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Localised JAK/STAT Pathway Activation Is Required for Drosophila Wing Hinge Development

Localised JAK/STAT Pathway Activation Is Required for Drosophila Wing Hinge Development

... instar wing imaginal disc are three prominent lateral folds, which we term the proximal (P), medial (M) and distal (D) folds (Figure 3 and ...the wing pouch and the future notum, and run ...

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Integration of Orthogonal Signaling by the Notch and Dpp Pathways in Drosophila

Integration of Orthogonal Signaling by the Notch and Dpp Pathways in Drosophila

... the wing imaginal disc, we refined the subset of 98 down to those that also had binding sites for three wing imaginal disc selectors: (i) Ap- terous (Ap), which is expressed ...

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