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Xpert® MTB/RIF assay

Evaluation of the Xpert® MTB/RIF assay and microscopy for the diagnosis of Mycobacterium tuberculosis in Namibia

Evaluation of the Xpert® MTB/RIF assay and microscopy for the diagnosis of Mycobacterium tuberculosis in Namibia

... with MTB than ...of MTB cases, but the lowest number of MTB cases was re- corded among the age group of below 20 years (see Table ...249 MTB-positive males, 190 (76.3%) tested posi- tive for ...

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Performance evaluation of the Xpert MTB/RIF assay according to its clinical application

Performance evaluation of the Xpert MTB/RIF assay according to its clinical application

... the Xpert assay does not perform equally well for all clinical applications of MTB detec- ...the Xpert assay per- formed equally well among patients with and without presumptive ...

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The Diagnostic Performance of the GenoType MTBDRplus Version 2 Line Probe Assay Is Equivalent to That of the Xpert MTB/RIF Assay

The Diagnostic Performance of the GenoType MTBDRplus Version 2 Line Probe Assay Is Equivalent to That of the Xpert MTB/RIF Assay

... The Xpert MTB/RIF assay was endorsed for use on patient material, regardless of smear gradation, while the GenoType MTBDRplus (version 1) has been limited for use on smear-positive patient ...

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Detection of Mycobacterium tuberculosis in Blood by Use of the Xpert MTB/RIF Assay

Detection of Mycobacterium tuberculosis in Blood by Use of the Xpert MTB/RIF Assay

... Role of anticoagulants in M. tuberculosis detection in blood. Our processing protocol requires anticoagulated blood samples. However, certain anticoagulants such as heparin or EDTA can inhibit PCR assays. We tested the ...

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DIAGNOSTIC UTILITY OF XPERT MTB/RIF ASSAY FOR DETECTION OF MYCOBACTERIUM TUBERCULOSIS AMONG SUSPECTED TUBERCULOUS PLEURAL EFFUSION PATIENTS WHILE TAKING AFB CULTURE AS GOLD STANDARD

DIAGNOSTIC UTILITY OF XPERT MTB/RIF ASSAY FOR DETECTION OF MYCOBACTERIUM TUBERCULOSIS AMONG SUSPECTED TUBERCULOUS PLEURAL EFFUSION PATIENTS WHILE TAKING AFB CULTURE AS GOLD STANDARD

... endorsed Xpert MTB/RIF assay for diagnosis of tuberculosis in ...of assay. [5] Gene Xpert has good diagnostic accuracy for pulmonary samples while in case of EPTB its accuracy is ...

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Tuberculous spondylitis diagnosed through Xpert MTB/RIF assay in urine: a case report

Tuberculous spondylitis diagnosed through Xpert MTB/RIF assay in urine: a case report

... The Xpert MTB/RIF assay has been widely implemented in sub-Saharan ...The Xpert MTB/RIF assay is able to detect both the presence of Mycobacterium tuber- culosis ...

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Assessment of the sensitivity and specificity of Xpert MTB/RIF assay as an early sputum biomarker of response to tuberculosis treatment

Assessment of the sensitivity and specificity of Xpert MTB/RIF assay as an early sputum biomarker of response to tuberculosis treatment

... quantitative Xpert MTB/RIF assay readouts for sputum M tuberculosis DNA as a biomarker correlate well with M tuberculosis smear and culture results during antituberculosis ...with Xpert ...

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Evaluation of the Analytical Performance of the Xpert MTB/RIF Assay

Evaluation of the Analytical Performance of the Xpert MTB/RIF Assay

... MTBDRplus assay was recently endorsed by the World Health Organization for rapid drug susceptibility testing of ...the Xpert MTB/RIF assay might also be deployed ...the Xpert ...

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Diagnostic accuracy of Xpert MTB/RIF assay for musculoskeletal tuberculosis: a meta-analysis

Diagnostic accuracy of Xpert MTB/RIF assay for musculoskeletal tuberculosis: a meta-analysis

... the Xpert assay was applied to diagnose musculoskeletal ...of Xpert for the diagnosis of musculoskeletal TB. Xpert was highly sensitive ...of Xpert for detecting musculoskeletal TB and ...

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Distribution and Frequency of rpoB Mutations Detected by Xpert MTB/RIF Assay Among Beijing and Non-Beijing Rifampicin Resistant Mycobacterium tuberculosis Isolates in Bangladesh

<p>Distribution and Frequency of <em>rpo</em>B Mutations Detected by Xpert MTB/RIF Assay Among Beijing and Non-Beijing Rifampicin Resistant <em>Mycobacterium tuberculosis</em> Isolates in Bangladesh</p>

... including Xpert MTB/RIF (Xpert) assay and the Line Probe Assay (LPA) can simultaneously detect Mycobacterium tuberculosis complex (MTBC) and drug resistance in both pulmonary and ...

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Retrospective Analysis of False Positive and Disputed Rifampin Resistance Xpert MTB/RIF Assay Results in Clinical Samples from a Referral Hospital in Hunan, China

Retrospective Analysis of False Positive and Disputed Rifampin Resistance Xpert MTB/RIF Assay Results in Clinical Samples from a Referral Hospital in Hunan, China

... be RIF susceptible by the MGIT system but RIF resistant by the Xpert assay, rather than on all cases that were Xpert RIF ...all Xpert RIF-resistant isolates had ...

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Improving the Sensitivity of the Xpert MTB/RIF Assay on Sputum Pellets by Decreasing the Amount of Added Sample Reagent: a Laboratory and Clinical Evaluation

Improving the Sensitivity of the Xpert MTB/RIF Assay on Sputum Pellets by Decreasing the Amount of Added Sample Reagent: a Laboratory and Clinical Evaluation

... The Xpert MTB/RIF (Xpert) assay permits rapid near-patient detection of Mycobacterium tuberculosis in sputum; however, the test sensitivity remains suboptimal in paucibacillary ...

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Xpert® MTB/RIF assay for extrapulmonary tuberculosis and rifampicin resistance

Xpert® MTB/RIF assay for extrapulmonary tuberculosis and rifampicin resistance

... evaluate Xpert® MTB/RIF by aspiration of gastric fluid, as this specimen is used mostly for investigating pulmonary TB in ...of Xpert® MTB/RIF to diagnose relapse of previ- ously ...

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The New Xpert MTB/RIF Ultra: Improving Detection of Mycobacterium tuberculosis and Resistance to Rifampin in an Assay Suitable for Point of Care Testing

The New Xpert MTB/RIF Ultra: Improving Detection of Mycobacterium tuberculosis and Resistance to Rifampin in an Assay Suitable for Point of Care Testing

... the Xpert MTB/RIF assay with better TB detection capabilities and more definitive identification of RIF susceptibility and resis- ...of Xpert supports this ...the assay will ...

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Trend of Pulmonary and Extrapulmonary Tuberculosis in Pediatric Group

Trend of Pulmonary and Extrapulmonary Tuberculosis in Pediatric Group

... by Xpert MTB/RIF assay (Cepheid-Sunnyvale-USA), as per the guidance document given by Central TB division, Government of India (RNTCP, 2013; RNTCP, ...as MTB detected, MTB not ...

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Evaluation of Xpert MTB/RIF testing for rapid diagnosis of childhood pulmonary tuberculosis in children by Xpert MTB/RIF testing of stool samples in a low resource setting

Evaluation of Xpert MTB/RIF testing for rapid diagnosis of childhood pulmonary tuberculosis in children by Xpert MTB/RIF testing of stool samples in a low resource setting

... TB: Xpert MTB/RIF assay, Cepheid, USA; TB: tuberculosis; MTB: Mycobac- terium tuberculosis; KJ: Kenneth-Jones; GA: gastric aspirates; Spm: sputum; TRS: treatment response standard; PPV: ...

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Laboratory Diagnosis of Mycobacterium tuberculosis Infection and Disease in Children

Laboratory Diagnosis of Mycobacterium tuberculosis Infection and Disease in Children

... the Xpert MTB/RIF assay. The assay detects rifampin (RIF) resistance, and results are available in hours as opposed to weeks or ...months. RIF resistance is frequently ...

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Rapid Detection of Cell Free Mycobacterium tuberculosis DNA in Tuberculous Pleural Effusion

Rapid Detection of Cell Free Mycobacterium tuberculosis DNA in Tuberculous Pleural Effusion

... the Xpert MTB/RIF assay (Xpert), the ...T-SPOT.TB assay (T-SPOT), the adenosine deaminase assay (ADA), and cf-TB are listed in the Table ...and Xpert, with the ...

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A Simple Microfluidic Assay for Diagnosing Tuberculous Meningitis in HIV Uninfected Patients

A Simple Microfluidic Assay for Diagnosing Tuberculous Meningitis in HIV Uninfected Patients

... the Xpert MTB/RIF assay as the initial diagnostic test for suspected TBM patients in preference to other tests, such as mycobacterial culture and ...the Xpert MTB/RIF ...

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Dried Culture Spots for Xpert MTB/RIF External Quality Assessment: Results of a Phase 1 Pilot Study in South Africa

Dried Culture Spots for Xpert MTB/RIF External Quality Assessment: Results of a Phase 1 Pilot Study in South Africa

... Criteria for a verification (“fit for purpose”) and EQA pro- gram suited to the characteristics of the Xpert MTB/RIF assay (3, 8) will require the following elements. (i) The testing ma- ...

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