Yes-associated protein 1 (YAP1)
Original Article Yes-associated protein 1 promotes bladder cancer invasion by regulating epithelial-mesenchymal transition
... March 1, 2019; Published March 15, 2019 Abstract: Purpose: To investigate the expression of Yes-associated protein 1 (YAP1) in bladder cancer, and to study its role in regulating ...
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Original Article Clinical significance of AJUBA, YAP1, and MMP14 expression in esophageal squamous cell carcinoma
... AJUBA, Yes-associated protein 1 (YAP1), and matrix metalloproteinase 14 (MMP14) in the clinical presentation and survival of ...of YAP1. High expression of MMP14 was ...
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Polyomavirus Small t Antigen Interacts with Yes-Associated Protein To Regulate Cell Survival and Differentiation
... both Yes-associated protein 1 (YAP1) and YAP2, inte- gral parts of the Hippo signaling pathway, which is a subject of increasing interest in human ...with protein phospha- tase ...
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Original Article Expression of miR-141 and YAP1 in gastric carcinoma and modulation of cancer cell proliferation and apoptosis
... Abstract: Yes-associated protein 1 (YAP1) plays important roles in facilitating cell proliferation and decreasing apop- tosis and is related to gastric ...is associated with ...
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Unraveling the expression of the oncogene YAP1 , a Wnt/beta- catenin target, in adrenocortical tumors and its association with poor outcome in pediatric patients
... Yes-associated protein 1 (YAP1) is a transcription factor-like protein, which belongs to the Hippo ...pathway. YAP1 plays an important role in growth control and organ ...
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Original Article Spliceosome-associated factor catenin b-like 1 accelerates ovarian cancer progression by inducing expression and nuclear accumulation of yes-associated protein
... for 1 hour, cells were incubated with YAP1 primary antibodies (1:100 dilution) overnight at ...a 1:500 dilution of a fluorescent tag (Alexa Fluor 488; Invitrogen) and conjugated with sec- ...
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Aberrant methylation of yes-associated protein (YAP1) as a potential biomarker in breast cancer
... of YAP1 gene showed that the aberrant methylation pattern was independent of the age, body mass index, meno- pausal status, histopathological type, tumor size, axillary lymph node involvement, and serum CA15–3 (p ...
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Original Article Expression of Yes-associated protein (YAP) in metastatic breast cancer
... tive; 1, positive (less than 30% of all cells stained); and 2, positive (greater than or equal to 30% of all cells ...negative; 1, weak; 2, moderate; and 3, strong. A product between 0 and 1 was ...
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Original Article Expression of Yes-associated protein (YAP) in breast phyllodes tumor
... of Yes-associated protein (YAP) and its phosphorylated form (pYAP) in phyllodes tumor (PT) of human breast and verify the clinical ...were associated with shorter disease-free survival (DFS) ...
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Original Article Overexpression of yes-associated protein contributes to apoptosis of lung cancer
... The plasmid of pcDNA3.1-hYAP was a kind gift from Dr Subham Basu (Cancer Research UK, London, UK). The plasmid of pOTB7-TP53 was purchased Proteintach (Proteintach, China) pcDNA3.1-hYAP or pOTB7-TP53 control or plas- mid ...
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Yes associated protein (YAP) is a negative regulator of chondrogenesis in mesenchymal stem cells
... after 1 day of culture in micromass prior to initiation of TGF-β1 treatment (Figure ...decreased 1 day after plating in micromass (Figure ...file 1). Downregulation of YAP at the protein level ...
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Yes-Associated Protein (Yap) Is Required for Early Embryonic Development in Zebrafish (Danio Rerio)
... and tails that bent toward the abdomen, moderate morphants had short bodies and curved trunks, and severe morphants had small trunks and completely indistinct bodies. Mortality was calculated at 48 hpf (Fig. 1E). No ...
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ORIGINALRESEARCH Curcumin Inhibits the Tumorigenesis of Breast Cancer by Blocking Tafazzin/Yes-Associated Protein Axis
... The protein samples were run on sodium dodecyl sulfate polyacryla- mide gel electrophoresis (SDS-PAGE), and transferred onto polyvinylidene fl uoride (PVDF) membrane (Thermo Fisher Scienti fi ...(anti-YAP, ...
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The role of Yes-associated protein (YAP) in vertebrate development
... stained sections showed a disorganized embryonic mesoderm and confirmed separation of the embryonic-extraembryonic border in E7.5 embryos, while E8.5 embryos showed excessive folding of the anterior neurectoderm and a ...
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Pre clinical and clinical study on Swasa Kasam and the drug of choice is Thuthuvalayathy Chooranam
... The effect of Thuthuvalayathy chooranam on certain biochemical parameters were examined and compared with those of the control group. The blood samples collected with heparinized bottles were centrifuged at 5000 rpm for ...
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The electoral effects of general strikes in Western Europe
... Table 1 presents the results for the baseline models using changes in social expendi- ture as a proxy for ...Table 1 (for model III, significance is just below a 90 percent confidence interval) and in ...
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Human Papillomavirus 16 E2 Regulates Keratinocyte Gene Expression Relevant to Cancer and the Viral Life Cycle
... were able to repress the expression of IFN- to similar extents, and all three repressed the expression of STAT1, although E2 was again the strongest repressor. These results demonstrate that all three viral proteins ...
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Analysis of the Seven-Member AAD Gene Set Demonstrates That Genetic Redundancy in Yeast May Be More Apparent Than Real
... (YPD). Glucose minimal medium (SD) contained 0.67% yeast novel cellular context, for instance, by adding or delet- nitrogen base (Difco Laboratories, Detroit), 0.5% ammonium ing a signal sequence that directs the ...
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MicroRNA-214-3p inhibits the stem-like properties of lung squamous cell cancer by targeting YAP1
... and YAP1 is the core transcription regulator of the Hippo signaling ...adaptor protein Salvador1 (Sav1) and ultimately results in YAP1 ...phorylated YAP1 is sequestered in the cytoplasm and ...
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Original Article Yes associated protein is a poor prognostic factor in well-differentiated lung adenocarcinoma
... We could observe that YAP was expressed in both of nucleus and cytoplasm of the tumor cells because cytoplasmic YAP is dephosphory- lated to translocate to nucleus. We expected, cytoplasmic and nuclear YAP expressions ...
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