[PDF] Top 20 Adipose tissue and its proinflammatory properties

... in adipose tissue in TNF transgenic mice and mice with defective peripheral TNF receptors have been shown to be metabolically beneficial (lean phenotype and peripheral insulin ...obesity. Tissue ... See full document

... the proinflammatory properties of adipose tissue depend on its localisation in ...pose tissue inflammation than ...key proinflammatory serum markers, namely, the NF-κB and ... See full document

... Adipose tissue is now recognised as endocrine and paracrine organ, whose function impacts on numerous physiological processes including inflammation, energy homeostasis, lipid and glucose metabolism [19, ... See full document

... enough to abolish inflammation. Indeed, combined deficiency of monocytes and lymphocytes was required to prevent inflammation following the injection of TF. We observed that TF induced chemokine production (MIP-1α and ... See full document

... in adipose tissue in chronic ...from adipose tissue, and increased systemic proinflammatory cytokine activity may play a role in the remodeling of adipose tissue and ... See full document

... Macrophage populations are highly heterogeneous, and several activation states of macrophages have been observed. This macrophage diversity has led to an effort to categorize the macrophage populations. The most preva- ... See full document

... of its adipose/fibroglandular composition, ranging from < 25% to > 75% ...fibroglandular tissue distribution in the breast, and are much more representative of the structural heterogeneity of ... See full document

... enhances proinflammatory M1 macrophage differentiation, whereas T cells secreting anti- inflammatory cytokines such as interleukin-4 (IL-4), IL-13, and IL-10 promote anti-inflammatory M2 macrophage development ... See full document

... connective tissue has been removed from the ...of adipose tissue blood flow, combined with the demonstrations by Madsen & Malc ho w- M0 ll er (1983) and Jamal & Saggerson (1988) that insulin ... See full document

... the adipose mass is mediated by adipo- cyte hypertrophy (enlarged adipocytes) or hyperplasia (increased cell ...of adipose tissue ...of proinflammatory cytokines, including TNF-α, IL-6, IL-8, ... See full document

... subcutaneous adipose tissue measured by CT or MRI and the risk of diabetes, and the results are inconsist- ...subcutaneous adipose tissue and diabetes risk in white and African Americans, but ... See full document

... in adipose tissue. Grandl and colleagues demonstrated that adipose depot-specific differences in the ECM regulate the differentiation of adipocyte precursor populations (Grandl et ...to ... See full document

... structures. Proinflammatory cytokines and adipokines promote inflammation and diseases associated with ...marrow adipose tissue; T2D, type 2 diabetes; NAFLD, nonalcoholic fatty liver disease; SCAT, ... See full document

... Obesity is a major issue in developed countries. Regulating thyroid hormones is a growingly popular adjunct in a comprehensive approach towards weight loss. Despite growing popularity, there is a lack of knowledge about ... See full document

... of adipose tissue compartments in response to chronic positive cal- orie ...balance. Adipose tissue expansion occurs dynamically through adipocyte hypertrophy and/or hyperplasia (8–15) and ... See full document

... Direct targeting of adipose tissue is still far from being a magic bullet for the treatment of obesity and type 2 dia- betes. However, new options arise by targeting BAT to increase energy expenditure. ... See full document

... Canine adipose derived stem cells (ASCs) provide a source of me- senchymal stem cells that are potentially beneficial for the therapy of osteoarthritis in veterinary medicine and are used in clinical practice ... See full document

... of its formation during gastrulation, and show that, with the exception of the male perigonadal depot, visceral and subcutaneous adipocytes are derived from this ... See full document

... The association between body fat mass and metabolic disease is not absolute, and the diagnosis of obesity is often a poor surrogate for the adverse health risks of increased body fat 5 . Various ‘‘obesity paradoxes’’ ... See full document

... in adipose, liver, and brain tissues, it will strengthen local cellular gluco- corticoid ...in adipose tissue me- diated by 11 β -HSD1 [6, 12 – ... See full document