[PDF] Top 20 Age-associated changes in human tear proteome
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Age-associated changes in human tear proteome
... with age, which could not be directly connected to ocular surface inflammation, included two cytoplasmic actin isoforms (ACTB and ACTG1), GSN, PFN1, CEACAM7 and ...the tear fluid of subjects suffering from ... See full document
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Cervicovaginal microbiome dysbiosis is associated with proteome changes related to alterations of the cervicovaginal mucosal barrier.
... is associated with increased acquisition of ...other changes to the mucosal barrier are thought to play important roles but human data are ...the human cervicovaginal proteome by ... See full document
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Age-associated changes in the blood brain barrier: Comparative studies in human and mouse
... using human autopsy material is post mortem sampling, with results difficult to interpret as they can be affected by agonal events, population variation, coexisting pathology and post mortem uptake of serum ... See full document
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Novel regional age associated DNA methylation changes within human common disease associated loci
... epigenetic changes that were more likely to be functional and, due to their co-location, would enable direct integra- tion into future locus-specific common disease investiga- ...As age impacts on the ... See full document
14
Resistance training for activity limitations in older adults with skeletal muscle function deficits: a systematic review
... Abstract: Human aging results in a variety of changes to skeletal ...the age-associated loss of muscle mass and is one of the main contributors to musculoskeletal impairments in the ... See full document
7
Genistein-induced proteome changes in the human endometrial carcinoma cell line, ishikawa
... The regulation of genes involved in cell cycle, DNA replication, DNA repair, and mitosis involves the function of many pro- teins, including E2F, UDG, and prohibitin. Using cDNA microarray analysis we previ- ously ... See full document
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Changes in the serum proteome associated with the development of hepatocellular carcinoma in hepatitis C-related cirrhosis
... based biomarker studies have been heavily criticised for potential bias in their design. This may arise from collection of the cancer and noncancer sera in a different manner, differing storage conditions or poor ... See full document
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Decreased IRF8 expression found in aging hematopoietic progenitor/stem cells.
... examined age- associated expression changes in long-term repopulating (LTR) murine HSCs,(5, 6) there are no studies examining the age-associated expression changes in similar ... See full document
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Analysis of the human serum proteome
... A major trend underlying current biological research is the development and application of analytical methods capable of making global measurements of entire biological sys- tems. These advances have created unique ... See full document
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Plasma proteome changes associated with refractory anemia and refractory anemia with ringed sideroblasts in patients with myelodysplastic syndrome
... explore proteome changes in the high risk RAEB-2 ...observed changes; there were 61, 56, and 55 significant changes observed in RCMD, RAEB-1 and RA-RARS, ...observed changes in plasma ... See full document
9
Plasmodium-associated changes in human odor attract mosquitoes
... Covariates associated with participants (age, sex, Hb, and tympanic temperature measured at T1) were tested, but removed from the model because they were not significant (P > ... See full document
11
Preclinical and post-treatment changes in the HCC-associated serum proteome
... to Q Ceramic Hyper D anion exchange resin (Pall) and proteins eluted with washes of decreasing pH. The m/z 11720 peak eluted at pH 7 and was subsequently applied to a C18 reverse phase column (Vydac) in 0.1% TFA. ... See full document
5
Plasma proteome changes associated with refractory cytopenia with multilineage dysplasia
... for age as well as for sex. However, matching the control group for age may be connected with some ...some proteome changes related to ...plasma proteome differences when compared ... See full document
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Innovative strategies to clinically characterize the human tear proteome : from fundamental exploration to ophthalmological relevance
... groups: age-re l a t e d , h o rmonal, pharmacologic, immunopathic, hyponutritional, dysgenic, infectious/inflamma- t o ry, traumatic, neurologic, and tantalic; second, a classification of the affected glands and ... See full document
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Dynamics of the Lipid Droplet Proteome of the Oleaginous Yeast Rhodosporidium toruloides
... and proteome levels, respectively. This indicated that the LD proteome changed more significantly than other cellular ...LD proteome in this study as well as others ...LD proteome, including ... See full document
13
The proteome of human brain microdialysate
... in human CSF, as the perfusion solution and therefore the brain microdialysate is composed mostly of CSF, or "artif- ical" CSF ...the human CSF map to the human microdialysate map, the ... See full document
9
Age Changes in Human Skin from 3 Years To 75 Years of Age
... Graham J S et al (1965) has studied the changes in the human skin. The changes in the skin are mainly due to prolonged exposure to sun. The collagen fibers of the dermis are found to be thickened ... See full document
159
Mapping the human membrane proteome: a majority of the human membrane proteins can be classified according to function and evolutionary origin
... is found in chromosome 11, implicating an expansion of the family through a gene duplication event. Recently Unc93B1 was reported to be involved in trafficking of toll receptors to endolysosomes and is proposed to be ... See full document
14
Tear biomarkers for keratoconus
... also associated with elevated inflammatory cytokine IL-6 in the corneal epithe- lium and in the tears of keratoconus ...Cultured human keratocyte cells (HKCs) stimulated with three different isoforms of ... See full document
7
Age-related changes in the joint position sense of the human hand
... clear age-related decline of joint posi- tion sense performance in a cohort of healthy ...between age-related changes in joint posi- tion sense and activities of daily living that rely on proper hand ... See full document
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