[PDF] Top 20 Alterations in immunoregulatory T cell subsets in active systemic lupus erythematosus
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Alterations in immunoregulatory T cell subsets in active systemic lupus erythematosus
... among subsets of human T cells exists in patients with systemic lupus erythematosus (SLE), we analyzed peripheral blood lymphocytes in SLE patients during active and inactive ... See full document
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Abnormalities of T cell signaling in systemic lupus erythematosus
... the T cell surface. In normal T cells, TCR stimulation leads to clustering of these rafts to aid formation of the immunological synapse, allowing for cognate interactions with corres- ponding ... See full document
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A defect of immunoregulatory T cell subsets in systemic lupus erythematosus patients demonstrated with anti 2H4 antibody
... erythematosus (SLE) patients was characterized with the anti-2H4 monoclonal antibody that defines the human suppressor inducer subset. The T4+2H4+ population of cells has been shown to be critical for the ... See full document
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Intestinal Dysbiosis Associated with Systemic Lupus Erythematosus
... ABSTRACT Systemic lupus erythematosus (SLE) is the prototypical systemic autoimmune disease in humans and is characterized by the presence of hyperactive immune cells and aberrant antibody ... See full document
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Detection of Antilymphocyte Antibody with Two Color Method in Systemic Lupus Erythematosus and Its Heterogeneous Specificities against Human T Cell Subsets
... The two-color method originally described by Van Rood et al. (Van Rood, J. J., A. Van Leeuwen, and J. S. Ploen. 1976. Simultaneous detection of two cell populations by two- color fluorescence and application to ... See full document
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Anti C1q antibodies antedate patent active glomerulonephritis in patients with systemic lupus erythematosus
... clinical manifestations of nephritis, at a time when the disease was active (Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) ≥ 4). Clinical nephritis was suspected if urinal- ysis ... See full document
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Effects of Major Epigenetic Factors on Systemic Lupus Erythematosus
... of cell growth and programmed cell death, additionally in B-cell negative selection [42-44] ...with active lupus, PKCδis not properly phosphorylated in response to some chemical ... See full document
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B cell abnormalities in systemic lupus erythematosus
... are active participants in humoral immune responses that lead to differentiation of ...with active SLE express CD154/TNFSF5/CD40 ligand, and homotypic CD154–CD40/TNFRSF5 interactions between B cells from ... See full document
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Genetic contribution to mesenchymal stem cell dysfunction in systemic lupus erythematosus
... of T follicular helper (Tfh) cells, a CD4 + T-cell subtype that helps B cells to generate affinity-matured antibodies, in lupus mice ...+ T-cell-secreted interferon-γ (IFN-γ) ... See full document
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Lupus Band Test in Systemic Lupus Erythematosus
... - lupus band test (LBT) - for the diagnosis of systemic lupus erythematosus (SLE) has been well ...LE cell phenomenon (p = ...disease, active skin lesions, or other laboratory ... See full document
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Immunoregulatory soluble CTLA 4 modifies effector T cell responses in systemic lupus erythematosus
... of lupus-associated autoantigens and assess whether the alternatively spliced isoform of CTLA-4, soluble CTLA-4 (sCTLA-4), contributes to immune regulation of autoantigen-specific immunity in systemic ... See full document
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Impaired T cell capping and receptor regeneration in active systemic lupus erythematosus Evidence for a disorder intrinsic to the T lymphocyte
... anti-T cell autoantibody. To determine whether a disorder intrinsic to the T cell exists in SLE, the T cell capping mechanism was selected as a model of cellular ...normal ... See full document
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Relationship between systemic lupus erythematosus T cell subsets, anti T cell antibodies, and T cell functions
... with systemic lupus erythematosus (SLE) had differing T cell T4+/T8+ ratios and that the ratio correlated with clinical features of the ...blood T cell subsets in ... See full document
13
Studies of immune functions of patients with systemic lupus erythematosus T cell subsets and antibodies to T cell subsets
... when T cells were treated before activation; there was no effect when treatment was performed after ...a T cell necessary for the generation of suppressor cells, rather than with mature, activated ... See full document
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Neurological Manifestations Of Children With Systemic Lupus Erythematosus
... Neurological Manifestations Of Children With Systemic Lupus Erythematosus ORIGINAL ARTICLE Neurological Manifestations of Children with Systemic Lupus Erythematosus W F Loh, MRCP, I M I Hussain, FRCP,[.] ... See full document
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Late Onset Systemic Lupus Erythematosus: Clinical and Immunological Characteristics
... Late Onset Systemic Lupus Erythematosus Clinical and Immunological Characteristics ORIGINAL ARTICLE Late Onset Systemic Lupus Erythematosus Clinical and Immunological Characteristics S K J Shaikh, MMe[.] ... See full document
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Alterations of the gut microbiome in Chinese patients with systemic lupus erythematosus
... It is well known that the human gut microbiome could be susceptible to the host’s genotype [10], age [11], sex [12] and diet [13]. The association of the gut microbiome with diseases may be diverse due to the above ... See full document
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Peripheral NK and B regulatory cell frequencies are altered with symptomatic exacerbation in generalized myasthenia gravis patients
... blood of patients at exacerbation stage may transfer to the neuromuscular junction, where immune cells obviously accumulate. At the stage of remission, NK cells might then transfer back to peripheral blood. It will be ... See full document
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Systemic lupus erythematosus
... Systemic lupus erythematosus (SLE) is a clinically heterogeneous disease, which is autoimmune in origin and is characterized by the presence of autoantibodies directed against nuclear ... See full document
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SYSTEMIC LUPUS ERYTHEMATOSUS
... The findings from necropsies of 14 cases of systemic lupus erythematosus from this series showed that all of the children had renal involvement with either typical glom erular lesions or[r] ... See full document
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