[PDF] Top 20 Analysis of the MTHFR C677T variant with migraine phenotypes

... a migraine trigger. When the MTHFR genotype groups were examined by comparing CC and CT genotypes to the homozygous TT genotype, the resulting regression models did not alter ...a migraine treatment ... See full document

... subgroup analysis was conducted in the Chinese (n = 1,991) and non-Chinese populations (n = ...that MTHFR C677T variant and T- allele expression were significantly associated with elevated ... See full document

... this analysis. Based on the results of the unrelated case- control analysis we assessed the family data under both additive and recessive inheritance models and considered "MO+MA" and "MA ... See full document

... the MTHFR C677T variant could increase the breast cancer and/or ovarian cancer risk in ...the MTHFR C677T polymorphism might have a different effect on breast cancer and/or ovarian ... See full document

... request). Analysis of relative gene expression data have been per- formed using real-time quantitative PCR and the 2–ΔΔCT method [16], the starting copy number of the unknown samples was determined in comparison ... See full document

... DNA samples were obtained from whole blood or buc- cal epithelial cells for molecular genetic analysis. Whole blood samples were collected at the time of the inter- view for all cases with depression that ... See full document

... of MTHFR polymorphisms between boys and girls showed higher frequencies of MTHFR variant allele(s) in girls for both ...carrying MTHFR 1298C and 677T variant alleles were not ... See full document

... The MTHFR C677T polymorphism, a C-to-T transition at position 677, induces the substitution of valine for alanine in codon ...the variant T alleles of this MTHFR polymor- phism reduced the ... See full document

... 18. Gormley P, Anttila V, Winsvold BS, Palta P, Esko T, Pers TH, Farh KH, Cuenca- Leon E, Muona M, Furlotte NA, Kurth T, Ingason A, McMahon G, Ligthart L, Terwindt GM, Kallela M, Freilinger TM, Ran C, Gordon SG, Stam AH, ... See full document

... for C677T. B. Funnel group for A1298C. MTHFR: methylenetetrahydrofolate ...our analysis that included 10 studies, the study population included Caucasian, Mid-Asian and ...with MTHFR ... See full document

... Abstract In genetic association studies of rare variants, the low power of association tests is one of the main challenges. In this study, we propose a new single ‐marker association test called C‐JAMP (Copula‐based ... See full document

... of C677T genotypes followed HWE and did not vary significantly from that of expected ...of MTHFR A1298C polymorphisms did not follow ...mutant variant of A1298C in this region was observed to be more ... See full document

... of MTHFR C677T, A1298C and MTRR A66G polymorphisms, and the differences in serum folic acid and ho- mocysteine levels, we further constructed a logistic regression model to explore the specific relationship ... See full document

... the MTHFR C677T or A1298C functional polymorphism which could both reduce enzyme activity of MTHFR, so it makes sense to research the association between these two MTHFR polymorphisms and ... See full document

... Mol Biol Rep 2012; 39: 5553-5560. [15] Jakubowska A, Rozkrut D, Antoniou A, Hamann U, Scott RJ, McGuffog L, Healy S, Sinilnikova OM, Rennert G, Lejbkowicz F, Flugelman A, An- drulis IL, Glendon G, Ozcelik H; OCGN, ... See full document

... A total of 50 participants were consecutively recruted by Clinical Nutrition and Nutrigenomic Division of Uni- versity of Rome Tor Vergata during three months from May 2013. Participation in the study included a complete ... See full document

... acid analysis revealed a decrease in the methionine level and a marked elevation in the plasma homocysteine level, whereas other essential amino acids were within normal ranges (methionine, ...acid analysis ... See full document

... the C677T have been reported to be associated with diminished enzyme activity and increased plasma homocysteine ...that C677T polymorphism was likely to be associ- ated with an elevated risk of MTX ... See full document

... MATERIALS AND METHODS This study was carried out on 150 angiographically documented CAD patients with at least 50% coronary artery stenosis or a history of coronary angioplasty or surgical revascularization in CARE ... See full document

... the MTHFR C677T polymorphism reflects that the model represents a closed system leading to intracellular conversion of cellular homocysteine to SAH as opposed to export of homo- cysteine into the ... See full document