[PDF] Top 20 Antigenic Properties of the Human Immunodeficiency Virus Envelope during Cell-Cell Fusion
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Antigenic Properties of the Human Immunodeficiency Virus Envelope during Cell-Cell Fusion
... fusing cell interface indicates that neutralizing humoral responses to the coreceptor-binding site may be extremely difficult, if not impossible, to ...intermediate envelope structures can be accessed at ... See full document
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Antigenic Properties of the Human Immunodeficiency Virus Transmembrane Glycoprotein during Cell-Cell Fusion
... arrested. Fusion intermediates were then examined for reactivity with various monoclonal antibodies (MAbs) against immunogenic cluster I and cluster II epitopes in the gp41 ...stromal cell-derived ... See full document
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Inhibition of human immunodeficiency virus type 1 (HIV 1) glycoprotein mediated cell cell fusion by immunor (IM28)
... the fusion of the membrane phospholip- ids of the host cells and gp41 before viral ...the fusion active form of the envelope ...to fusion, i.e., fusion glycoproteins and the ... See full document
6
Amphotericin B derivative blocks human immunodeficiency virus type 1 entry after CD4 binding: effect on virus-cell fusion but not on cell-cell fusion.
... lipidic envelope with the cell membrane is usually addressed indirectly, by syncytium formation assays between CD4 1 cells and cells expressing HIV-1 envelope proteins (Env gp120 and Env ...Although ... See full document
5
Limited Breadth of a T-Helper Cell Response to a Human Immunodeficiency Virus Envelope Protein
... 1035 envelope sequence for the BH10 envelope sequence in a pSC11-based VV recombination ...for fusion. We selected this time point for fusion because the response to VV peaks relatively late ... See full document
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Inhibition of human immunodeficiency virus type 1-induced cell fusion by recombinant human interferons.
... In order to evaluate the effect of IFNs on the cell fusion induced by the HIV-1 envelope protein with another assay system, HeLa T4 cells were cocultivated with HeLa cells infected with [r] ... See full document
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Membrane-Fusing Capacity of the Human Immunodeficiency Virus Envelope Proteins Determines the Efficiency of CD4+ T-Cell Depletion in Macaques Infected by a Simian-Human Immunodeficiency Virus
... in virus-infected cultures include the forma- tion of multinucleated syncytia and the lysis of single cells (12, 19, 66, ...viral envelope glycoproteins (6, 34, 38, 40, 45, 65). The HIV-1 envelope ... See full document
10
Analysis of the cell fusion activities of chimeric simian immunodeficiency virus-murine leukemia virus envelope proteins: inhibitory effects of the R peptide.
... established human cell lines resulted in truncation of the SIV envelope protein, leaving 17 amino acids in the cytoplas- mic tail (5, ...its fusion activity in various cell types and ... See full document
7
CD4 molecules with a diversity of mutations encompassing the CDR3 region efficiently support human immunodeficiency virus type 1 envelope glycoprotein-mediated cell fusion.
... Each vaccinia virus-encoded mutant CD4 was expressed on a human cell type and tested for syncytium formation upon mixing with cells expressing HIV-1 envelope glycoprotein.. Cell-cell fus[r] ... See full document
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Promiscuous use of CC and CXC chemokine receptors in cell-to-cell fusion mediated by a human immunodeficiency virus type 2 envelope protein.
... expressing human chemokine receptors. cDNAs for the human chemokine receptors CXCR1, CXCR2, CXCR4, and CCR1 to CCR5 were isolated by RT-PCR essentially as described previously (43) and cloned into pcDNA1neo ... See full document
11
Promonocytic U937 subclones expressing CD4 and CXCR4 are resistant to infection with and cell-to-cell fusion by T-cell-tropic human immunodeficiency virus type 1.
... rVV-based fusion assays. Recombinant vaccinia virus (rVV) vTF7-3 (express- ing T7 RNA polymerase), vCB21R (encoding the lacZ gene under the control of the T7 promoter), vCB41 (expressing HIV-1 IIIB ... See full document
8
Enhancement of Human Immunodeficiency Virus Type 1 Infection by the CC-Chemokine RANTES Is Independent of the Mechanism of Virus-Cell Fusion
... on human immunodeficiency virus type 1 (HIV-1) infection, focusing on the infectivity enhancement caused by ...the envelope glycoprotein of murine leukemia virus or vesicular stomatitis ... See full document
11
Calcium ions are required for cell fusion mediated by the CD4-human immunodeficiency virus type 1 envelope glycoprotein interaction.
... To examine the role of calcium ions for cell fusion mediated by interactions between CD4 and the human immunodeficiency virus type 1 HIV-1 envelope glycoprotein gpl20-gp4l, we used two e[r] ... See full document
6
Temperature dependence of cell-cell fusion induced by the envelope glycoprotein of human immunodeficiency virus type 1.
... of cell-cell ...the cell surface area in contact with the substrate was increased 125-fold ...in cell spreading, or because the adhesion molecules are attached to cortical actin filaments ... See full document
11
Role of the Membrane-Spanning Domain of Human Immunodeficiency Virus Type 1 Envelope Glycoprotein in Cell-Cell Fusion and Virus Infection
... of fusion pore formation, we determined whether truncation of the cytoplas- mic domain of HIV-1 Env could relieve the defect observed in the absence of the glycine ...pseudotyped virus single-cycle assays ... See full document
12
Feline Immunodeficiency Virus (FIV) Envelope Glycoprotein-Mediated Cell Fusion and Apoptosis.
... env-mediated fusion at a post lipid mixing stage (Kliger et ...like properties and binds to galactosyl ceramide (Gal Cer) in a galactose specific fashion (Alfsen et ...second fusion domain in HIV ... See full document
113
Expression of Glucose Transporter 1 Confers Susceptibility to Human T-Cell Leukemia Virus Envelope-Mediated Fusion
... malian cell types are infectible and yet viral titers are uniformly poor or low, even when pseudotyped particles are used for infectivity ...viral envelope expression or stability, immediate postentry ... See full document
9
Human T-Cell Responses to Vaccinia Virus Envelope Proteins
... vaccinia virus (VACV). The products of the VACV envelope genes A27L, L1R, B5R, and A33R induce protective antibodies in animal ...vidual envelope proteins A27, B5, L1, and A33, using gamma interferon ... See full document
11
Depletion of the surface CD4 molecule by the envelope protein of human immunodeficiency virus expressed in a human CD4+ monocytoid cell line.
... By transferring this plasmid into a CD4+ human monocytoid cell line, we examined the effects of an envelope protein produced in cells on the expression of the CD4 molecule and found the [r] ... See full document
7
Cellular tropism and cell to cell fusion properties of the infectious bronchitis virus spike glycoprotein
... vaccinia virus DNA was extracted by ...purified virus in a 50 ml Falcon tube and incubated for ...vaccinia virus DNA solution was divided into two equal volumes in 15 ml Falcon ... See full document
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