[PDF] Top 20 Binding of human factor VII and VIIa to monocytes
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Binding of human factor VII and VIIa to monocytes
... Factors VII and VIIa bind with equal affinity to monocytes stimulated with ...Equilibrium binding studies performed at 0 degrees C using 125I-labeled Factor VII and VIIa ... See full document
11
Requirement for binding of catalytically active factor VIIa in tissue factor dependent experimental metastasis
... of human melanoma cells ...by binding to the preformed TF–VIIa complex at an epitope that includes Lys165 and Lys166, thus competing for factor X ac- cess and activation ...on human TF, ... See full document
8
Overview of the use of recombinant factor VIIa in children
... when factor VII binds to TF, no further reaction takes ...circulating factor VII is activated. The binding of activated factor VII (FVIIa) to TF causes the formation of a ... See full document
8
Tissue factor expression by endothelial cells in sickle cell anemia
... to Factor VII/VIIa (E), and binding is abolished with a block- ing antibody to TF (F, in which the faint CEC is indicated by an ...Factors VIIa and X exhibits Factor X ... See full document
7
Factor VIIa and Factor IXa Inhibitors as Anticoagulants: A Review
... Our human body is designed to maintain a complex network of vasculature that is capable of continuously circulating blood for decades. It is also responsible for its own repair when internal or external forces ... See full document
8
Use of Recombinant Factor VIIa in Obstetrics
... tissue factor is exposed at sites of injury and activated platelets are ...of factor IX to factor IXa and factor X to factor Xa following the binding of FVIIa to exposed tissue ... See full document
14
Demonstration and characterization of specific binding sites for factor VIII/von Willebrand factor on human platelets
... platelets. Binding is ristocetin-dependent and increases in proportion to the concentration of ristocetin from ...mg/ml. Binding of 125I-FVIII/vWF to platelets can be competitively inhibited by unlabeled ... See full document
10
Use of human factor VIIa in the treatment of two hemophilia A patients with high titer inhibitors
... pure human Factor ...with Factor VIIa the circumference of the muscle decreased and joint mobility increased ...given Factor VIIa concurrent with tranexamic acid in association ... See full document
7
The peri-kappa B site mediates human immunodeficiency virus type 2 enhancer activation in monocytes but not in T cells.
... through binding of the transcription factor NF- k B to two adjacent k B sites in the HIV-1 long terminal repeat, activation of the HIV-2 enhancer in monocytes and T cells is dependent on four ... See full document
9
Off-Label Use of Recombinant Factor VIIa in Pediatric Patients
... The Haemostasis Registry, established by the Department of Epidemiology and Preventive Medicine, Monash Univer- sity, is a register designed to collect data on all off-label rFVIIa use in patients treated at ... See full document
10
Tissue Factor and Cancer Metastasis: The Role of Intracellular and Extracellular Signaling Pathways
... Upon binding of activated factor VIIa (FVIIa), a coagulation factor circulating at low levels within the blood- stream, the so-formed TF/FVII complex initiates the extrinsic coagulation ... See full document
6
Functional Analysis of the Human Antibody Response to Meningococcal Factor H Binding Protein
... FH binding, we expected the anti-FHbp bactericidal activity to depend largely on the classical complement pathway since the alternative pathway would be downregulated by the bound ...the human anti-FHbp ... See full document
11
Müller, Ingrid (2003): Funktion und Aktivierungsmechanismus eines schnell aktivierbaren Tissue Factor-Systems. Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... Frühere Befunde lassen vermuten, daß von Blutzellen abgegebene Mikrovesikel Tissue Factor enthalten könnten (Berckmans, 2001). Um dies zu überprüfen, analysierten wir, ob Blut gesunder Spender zirkulierende ... See full document
91
Insulin Binding to Monocytes and Insulin Action in Human Obesity, Starvation, and Refeeding
... Insulin binding to monocytes and insulin action in vivo was examined in 14 obese subjects during the postabsorptive state and after starvation and ...I-Insulin binding to monocytes averaged ... See full document
11
Intrapulmonary Recombinant Factor VIIa for Diffuse Alveolar Hemorrhage in Children
... Recently, adult studies have reported the successful use of intrapulmonary rFVIIa for DAH. Even in severe macroscopic pulmonary bleeding, patients have been shown to respond rapidly. These effects are due to combined ... See full document
7
Immunoglobulins cytophilic for human lymphocytes, monocytes, and neutrophils
... of human myeloma proteins of different classes and subclasses for lymphocytes, monocytes, and neutrophils was ...investigated. Binding of both unaggregated immunoglobulins (Ig) and Ig aggregated with ... See full document
10
The utility of recombinant factor VIIa as a last resort in trauma
... additional factor that must be considered is the impact of other variables, such as rate of bleeding and baseline physiologic factors on rFVIIa, particularly tem- ... See full document
6
Pediatric Off-label Use of Recombinant Factor VIIa
... recombinant factor VIIa for off- label ...recombinant factor VIIa were disseminated intravascular coagulation/sepsis (28), surgical bleeding (19), proce- dural prophylaxis (16), and trauma ... See full document
9
The activation of factor X and prothrombin by recombinant factor VIIa in vivo is mediated by tissue factor
... via Factor VIIa-dependent activation of Factor X, but direct proof has not been available for the participation of tissue factor in this ...recombinant Factor VIIa (approximately ... See full document
7
Synthesis and biological evaluation of aeruginosin based compounds and self-assembly of glucosamine based compounds
... The crystal structure of the ternary complex revealed some unexpected interactions between 1 and the binding pocket of thrombin. l-Leu was found to occupy the hydro-phobic d- enantiomorphic S3 subsite, despite its ... See full document
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