[PDF] Top 20 Biosynthesis and biochemical properties of the hepatitis C virus core protein.

... Processing of the translation products was dependent on microsomal membranes and signal recognition particle, suggesting that release of the 21-kDa core protein from the polyprotein prec[r] ... See full document

... HCV core protein plays a role in insulin resistance ...HCV core protein enhanced the promoter activity of the TNF- ␣ gene in human liver cell lines but not in those with a knockdown of the ... See full document

... HCV core protein led us to analyze whether cytoplasmic and nuclear core proteins have different ...HCV core protein. This finding and the truncated protein expression pattern in ... See full document

... Hepatitis C virus (HCV) infection represents one of the most important factors for the generation of chronic hep- atitis, liver cirrhosis and hepatocellular carcinoma ...the virus in 1989 [4], ... See full document

... binding properties of hepatitis C virus (HCV) core protein and its viral RNA for the encapsidation, morphogenesis, and replication of HCV, the specific interaction of HCV ... See full document

... HCV core protein has many intriguing properties, including immortal- ization of primary human hepatocytes (PHH) (18) and induction of EMT (19, 20) and CSCs ...binding protein 1 (ID1) proteins, ... See full document

... the core protein have been reported (13, 38, 50), yet because infectious HCV particles cannot be appro- priately produced in currently available experimental systems, HCV particle assembly has not been ... See full document

... 7 0022-538X/91/073489-07$02.00/0 Copyright C 1991, American Society for Microbiology Biosynthesis of the Secretory Core Protein of Duck Hepatitis B Virus: Intracellular Transport, Proteo[r] ... See full document

... Hepatitis C virus (HCV) core protein features many intriguing properties and plays a pivotal role in cellular immunity, cell growth, apoptosis, cell transformation, and ... See full document

... HCV core sequence analysis and design of expressed pro- ...The biochemical and biophysical characterizations of HCV core protein require the mature core ...of core ... See full document

... a C-terminal deletion, but not with the N-terminal deletion, failed to inter- act with the HCV core protein (Table ...The C-terminal regions of CAP-Rf deleted (residues 473 to 661) comprise ... See full document

... Hepatitis C virus (HCV) core protein is essential for virus ...HCV core protein was expressed and purified. Aptamers against core protein were raised ... See full document

... Persistent hepatitis C virus (HCV) infection is a major cause of chronic liver dysfunction in humans and is epidemiologically closely associated with the development of human hepatocellular ... See full document

... HCVcc core proteins are indeed envel- oped by a ...of core envelopment by differential membrane ...of core envelopment is defined as [(T ⫺ S)]/T ⫻ ...and C) JFH1 RNA-transfected Huh7 cells ... See full document

... HCV core gene were gener- ated as described [9,10,17]. Briefly, the HCV core gene (genotype 1b) was cloned into PUGH10-3 downstream of the tetracycline response element (TRE) ...activating protein ... See full document

... envelope protein was ex- pressed by ...envelope protein does not cross-react with our anti-core ...E1 protein was faithfully expressed in this experiment, an aliquot of the same cell lysate ... See full document

... a virus in order to allow enhanced virus production before ...viral protein EBNA-1 which is the only protein produced in latently-infected cells is resistant to proteolysis by the proteasome ... See full document

... E1 protein in the mem- ...the C- terminal transmembrane domain (residues 360 to 383) are important for ER retention ...the C-terminal hydro- phobic region, the amino acid sequence of the central ... See full document

... HCV core protein was used for ...the protein-protein ...R-associated protein TRAF3 also binds to the same C-terminal region of LT b ...HCV core protein to LT b R ... See full document

... Hepatitis C virus (HCV) has been identified as the major causative agent of parenterally transmitted non-A, non-B hep- atitis ...capsid protein which are predominantly recognized by HCV- ... See full document