[PDF] Top 20 CD133 as a Biomarker of Thyroid Cancer Stem Cells

... of CD133 + VEGFR2 + and CD34 + VEGFR2 + in thalassemia patients is accompanied by vascular dysfunction (Cheung et ...of CD133 protein were nearly associated with angiogenesis, poor stage, and metastasis of ... See full document

... tumor cells contributing to metastasis has the properties of CSCs or ...TICs. CD133 + cells are higher in liver metastasis than in primary colorectal tumors ...with CD133 + CXCR4 - ... See full document

... liver cancer cell line, PLC/PRF/5 that expressed the hepatitis B surface antigen ...in CD133 + PLC/PRF/5 cells. The proteomics results of PLC/PRF/5 cells are listed in Additional file 5: Table ... See full document

... on cancer stem cells has opened up new avenues to accelerate the development of novel diagnostic and treatment ...Most cancer research experts focused on isola- tion and targeted killing of ... See full document

... Objective: CD133 has been recognized as a marker of cancer stem-like cells in esophageal ...of CD133 and clinicopathological features and the prognosis of esophageal ...of CD133 ... See full document

... of CD133 (+) ...hepatocellular cancer [17, ...embryonic stem cells (ESCs) by regulating the balance between proliferation and differentiation through miR-122/FoxA1/ HNF4α positive feedback ... See full document

... neoplasms. Cancer stem cells have been implicated in tumor initiation, progression, metastatic potential and resistance to ...and CD133 expression level as cancer stem cell ... See full document

... 6 cells/ml Aldefluor assay buffer, according to the protocol recom- mended by the ...human cells, was included. On some occasions the cells were subsequently labeled with one of the following ... See full document

... the cells were incubated with 10 μl of phycoerythrin-conjugated (PE) anti-human CD133 monoclonal antibody (mAb) (Miltenyi Biotech), 10 μl of allophycocyanin-conjugated (APC) anti- human VEGFR-2 mAb ... See full document

... important cancer stem cells factors, including SOX2, OCT4, CD133, NANOG and ALDH1A3, with the and prognosis of patients with RCC, Kaplan–Meier survival analyses were performed on patients in ... See full document

... hours; cells of treated and control groups were collected and digested with ethylene diamine tetraacetic acid (EDTA) ...trypsinase. Cells were collected, washed twice with ice-cold PBS, and then ... See full document

... important biomarker of a cellular subpopulation – cancer stem cells (CSCs) – which are capable of self-renewal and have the capacity for initiation, progression, invasion, metastasis, tumor ... See full document

... Based on the above findings and the fact that Bmi1 regulate the expression of the Ink4a locus which encodes for two tumor suppressor pro- teins p16Ink4a and p14Arf, thereby regulating cell proliferation and senescence ... See full document

... DNA: Deoxyribonucleic acid; EDTA: Ethylene diamine tetra acetic acid; FACS: Fluorescent-activated cell sorting; gp100: Melanosomal matrix protein; HEPES: 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; IGF-1: ... See full document

... as; cells with high ALDH had a large formation of spheres whilst when they had low ALDH there was no formation of ...in cancer stem cells. Similar results were obtained for CD133 as a ... See full document

... inflammatory cells. Conversely, CD133 expression does not identify the entire population of epithelial and tumor-initiating cells in human metastatic colon ...both CD133 + and CD133 – ... See full document

... the cells were treated with free coumarin 6 or C6-NP for 2 hours at 37 ° C, which had an equivalent concentration of coumarin 6 (15 ...the cells were fixed with 4% paraformal- dehyde. The cells were ... See full document

... Previous studies have revealed the oncogenic and tumor suppressor roles of miRNAs during the formation and progression of tumors through the pathway modula- tion. Furthermore, several miRNAs have been reported closely ... See full document

... The small size of our prepared nanomicelles (~ 20 nm) may be beneficial for their targeting efficacy for lung CSCs, since the size of nanoparticles is critical for their tumor penetration [35–37]. Cabral reported that ... See full document

... so-called cancer stem cell (CSC) holds that only a minority of cells within a tumor have the ability to generate a new ...protein CD133 as a marker of organ-specific adult stem ... See full document