[PDF] Top 20 Characterization of T-Cell Responses in Macaques Immunized with a Single Dose of HIV DNA Vaccine
Has 10000 "Characterization of T-Cell Responses in Macaques Immunized with a Single Dose of HIV DNA Vaccine" found on our website. Below are the top 20 most common "Characterization of T-Cell Responses in Macaques Immunized with a Single Dose of HIV DNA Vaccine".
Characterization of T-Cell Responses in Macaques Immunized with a Single Dose of HIV DNA Vaccine
... in macaques induced sustained CD8 ⫹ T-cell re- sponses predominantly composed of proliferating T cells with lytic granzyme B content, suggesting that the nature of T-cell IR ... See full document
11
Sustained Peptide-Specific Gamma Interferon T-Cell Response in Rhesus Macaques Immunized with Human Immunodeficiency Virus gag DNA Vaccines
... ELISPOT responses of rhesus monkeys to HIV gag DNA vac- ...of HIV gag plasmid DNA vaccine at weeks 0, 4, 8, and ...the HIV Gag ...a single dominant ...robust ... See full document
6
Superior Induction of T Cell Responses to Conserved HIV-1 Regions by Electroporated Alphavirus Replicon DNA Compared to That with Conventional Plasmid DNA Vaccine
... “naked” DNA is a highly attractive strategy for induction of pathogen-specific immune responses; however, it has been only weakly immunogenic in ...constructed DNA-launched Semliki Forest virus ... See full document
9
Strong HIV-Specific CD4+ and CD8+ T-Lymphocyte Proliferative Responses in Healthy Individuals Immunized with an HIV-1 DNA Vaccine and Boosted with Recombinant Modified Vaccinia Virus Ankara Expressing HIV-1 Genes
... proliferative responses by vaccination group. The overall HIV-specific T-cell proliferative response in the vac- cinees employing any of the three assays was 100% ...compare ... See full document
8
Increased, Durable B-Cell and ADCC Responses Associated with T-Helper Cell Responses to HIV-1 Envelope in Macaques Vaccinated with gp140 Occluded at the CD4 Receptor Binding Site
... When HIV-1 gp120 binds to CD4, it stabilizes the virus envelope in a conformation that presents an increased affinity for the chemokine receptors and CD4i antibodies ...during HIV-1 infection (32, 45, 46) ... See full document
15
Effect of Plasmid DNA Vaccine Design and In Vivo Electroporation on the Resulting Vaccine-Specific Immune Responses in Rhesus Macaques
... All HIV genes used in this study, including gag p55 (HXB2), pol (HXB2), nef (NL4-3), tat (NL4-3), vif (NL4-3), and env gp160 (from primary isolate 6101 from David Montefiori; gene bank accession ...a single ... See full document
13
Low-Dose Penile SIVmac251 Exposure of Rhesus Macaques Infected with Adenovirus Type 5 (Ad5) and Then Immunized with a Replication-Defective Ad5-Based SIV gag/pol/nef Vaccine Recapitulates the Results of the Phase IIb Step Trial of a Similar HIV-1 Vaccine
... candidate HIV vaccines, especially those de- signed to elicit effector T cell responses ...of HIV sexual transmission can reflect the results of human clin- ical trials of AIDS ...of ... See full document
12
The HIV/AIDS Vaccine Candidate MVA-B Administered as a Single Immunogen in Humans Triggers Robust, Polyfunctional, and Selective Effector Memory T Cell Responses to HIV-1 Antigens
... promising HIV/AIDS vaccine candidates. Here, we describe the nature of T cell immune responses induced in healthy volunteers participating in a phase I clinical trial in Spain after ... See full document
11
Characterization of T-Cell Responses to Conserved Regions of the HIV-1 Proteome in BALB/c Mice
... protective vaccine against human immunodeficiency virus type 1 (HIV-1)/AIDS is, in addition to elic- iting antibody responses, induction of effective T ...tackle HIV-1 diversity by ... See full document
8
Enhanced Control of Pathogenic Simian Immunodeficiency Virus SIVmac239 Replication in Macaques Immunized with an Interleukin-12 Plasmid and a DNA Prime-Viral Vector Boost Vaccine Regimen
... RMs immunized with live attenuated viruses, such as SIVmac239 ⌬ Nef or rhCMV (10, ...rhCMV vaccine model was associated with the induction of long-lived SIV-specific T cells with an effector memory ... See full document
10
Host Genetic Determinants of T Cell Responses to the MRKAd5 HIV-1 gag/pol/nef Vaccine in the Step Trial.
... immune responses to the MRKAd5 HIV-1 gag/pol/nef vaccine tested in the Step trial, we performed a genome-wide association study of determinants of HIV-specific T cell ... See full document
22
Characterization of Antibody Responses to Combinations of a Dengue Virus Type 2 DNA Vaccine and Two Dengue Virus Type 2 Protein Vaccines in Rhesus Macaques
... of DNA, re- combinant subunit, and purified inactivated virus vaccines in rhesus ...immune responses to vaccination by measuring dengue virus- neutralizing antibody, total antibody, and antibody avidity and ... See full document
9
Protective Mechanisms Induced by a Japanese Encephalitis Virus DNA Vaccine: Requirement for Antibody but Not CD8+Cytotoxic T-Cell Responses
... pE DNA vaccine produced only anti-E ...or T-cell-enriched immune splenocytes from pE- or live-JEV- immunized animals did not provide significant protection against a lethal JEV ... See full document
7
A human immune data informed vaccine concept elicits strong and broad T cell specificities associated with HIV 1 control in mice and macaques
... novel HIV-1 T-cell immunogen that has been rationally designed to maximize the induction of effective anti-viral T cell ...to HIV-1, which allowed for the identifica- tion and ... See full document
23
Prevention of Adult T-Cell Leukemia-Like Lymphoproliferative Disease in Rats by Adoptively Transferred T Cells from a Donor Immunized with Human T-Cell Leukemia Virus Type 1 Tax-Coding DNA Vaccine
... virus-transformed T- cell lines can be established in rats in vitro (19, ...HTLV-1-specific T cells in inhibiting the growth of HTLV-1- infected tumor cells in vivo ...that DNA vaccines with ... See full document
7
HIV-1 Reservoir Dynamics after Vaccination and Antiretroviral Therapy Interruption Are Associated with Dendritic Cell Vaccine-Induced T Cell Responses
... the vaccine-induced T cell immune re- sponse could be driven by the type of immunogen ...therapeutic vaccine clinical trials performed with het- erologous antigens did not find any virological ... See full document
11
Enhanced specific immune responses by CpG DNA in mice immunized with recombinant hepatitis B surface antigen and HB vaccine
... The T cell immune response requires co-stimulatory signals delivered through one or more receptors on the surface of T ...for T cell activa- tion and survival ...of T cell ... See full document
6
Single dose denileukin diftitox does not enhance vaccine-induced T cell responses or effectively deplete Tregs in advanced melanoma: immune monitoring and clinical results of a randomized phase II trial
... Other strategies to deplete or modulate Tregs in can- cer patients are being explored and remain worthy of de- velopment. Cyclophosphamide has long been suggested to have modulating effects on Tregs, and ongoing clinical ... See full document
9
HIV-Exposed Infants Vaccinated with an MF59/Recombinant gp120 Vaccine Have Higher-Magnitude Anti-V1V2 IgG Responses than Adults Immunized with the Same Vaccine
... immune responses in the placebo groups, we combined the two placebo arms in AVEG 201 and the two placebo arms in PACTG ...4th dose) analyses were performed using visit 11 (day 378) for AVEG 201 and week 24 ... See full document
14
Induction of Human Immunodeficiency Virus Type 1 (HIV-1)-Specific T-Cell Responses in HIV Vaccine Trial Participants Who Subsequently Acquire HIV-1 Infection
... acquired HIV-1 infection. The vac- cine constructs contained full-length gag (HIV-1 LAI) and env gp120 (HIV-1 MN) coding regions, with some constructs also containing parts of pol and ...I/II ... See full document
10
Related subjects