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[PDF] Top 20 Characterization of Low-Pathogenic H5 Subtype Influenza Viruses from Eurasia: Implications for the Origin of Highly Pathogenic H5N1 Viruses

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Characterization of Low-Pathogenic H5 Subtype Influenza Viruses from Eurasia: Implications for the Origin of Highly Pathogenic H5N1 Viruses

Characterization of Low-Pathogenic H5 Subtype Influenza Viruses from Eurasia: Implications for the Origin of Highly Pathogenic H5N1 Viruses

... Systematic influenza surveillance of domestic poultry in Hong Kong and southern China was conducted from 1976 to 1980 and 2000 onwards, while surveillance of migratory bird populations in southern China has ... See full document

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Growth and Pathogenic Potential of Naturally Selected Reassortants after Coinfection with Pandemic H1N1 and Highly Pathogenic Avian Influenza H5N1 Viruses

Growth and Pathogenic Potential of Naturally Selected Reassortants after Coinfection with Pandemic H1N1 and Highly Pathogenic Avian Influenza H5N1 Viruses

... swine origin influenza virus infection were first reported in the United States by the Centers for Disease Control and Prevention (CDC) on 29 April ...pandemic influenza of the 21st century by WHO in ... See full document

8

Characterization of the H5N1 Highly Pathogenic Avian Influenza Virus Derived from Wild Pikas in China

Characterization of the H5N1 Highly Pathogenic Avian Influenza Virus Derived from Wild Pikas in China

... The highly pathogenic H5N1 avian influenza virus emerged from China in 1996 and has spread across Eurasia and Africa, with a continuous stream of new cases of human infection ... See full document

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Surveillance for Eurasian origin and intercontinental reassortant highly pathogenic influenza A viruses in Alaska, spring and summer 2015

Surveillance for Eurasian origin and intercontinental reassortant highly pathogenic influenza A viruses in Alaska, spring and summer 2015

... HP H5 IAVs and potential progeny ...collection from western Alaska; however, we isolated five low pathogenic (LP) ...Genetic characterization of these five LP IAVs isolated from ... See full document

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Genetic Evidence Supports Sporadic and Independent Introductions of Subtype H5 Low-Pathogenic Avian Influenza A Viruses from Wild Birds to Domestic Poultry in North America

Genetic Evidence Supports Sporadic and Independent Introductions of Subtype H5 Low-Pathogenic Avian Influenza A Viruses from Wild Birds to Domestic Poultry in North America

... for H5 IAVs detected in domestic poultry, and shorebirds were supported as a probable progenitor for only one gene segment for a single introduction event [MP gene of ...segments from North American poultry ... See full document

16

Molecular characterization of highly pathogenic H5N1 avian influenza viruses isolated in Sweden in 2006

Molecular characterization of highly pathogenic H5N1 avian influenza viruses isolated in Sweden in 2006

... by highly pathogenic avian influenza viruses (HPAIV) of H5N1 subtype in 1996 originated from southern China ...Systematic influenza surveillances showed that ... See full document

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Characterization of Low-Pathogenicity H5N1 Avian Influenza Viruses from North America

Characterization of Low-Pathogenicity H5N1 Avian Influenza Viruses from North America

... the H5 HA, the ecology of AI virus, and the ability of wild birds to disseminate influenza ...to H5 is due to the Asian H5N1 HPAI virus and human health concerns, the H5 subtype ... See full document

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Highly Pathogenic Avian Influenza Virus Subtype H5N1 Escaping Neutralization: More than HA Variation

Highly Pathogenic Avian Influenza Virus Subtype H5N1 Escaping Neutralization: More than HA Variation

... obtained from an animal that was only vaccinated but not challenged, through the first 18 passages induced only three amino acid ...sera from animals challenged with infectious virus contained a broader ... See full document

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Live Attenuated Influenza Viruses Containing NS1 Truncations as Vaccine Candidates against H5N1 Highly Pathogenic Avian Influenza

Live Attenuated Influenza Viruses Containing NS1 Truncations as Vaccine Candidates against H5N1 Highly Pathogenic Avian Influenza

... vaccine viruses. With the aim of developing live attenuated vaccines of the H5 subtype, a panel of eight recombinant viruses based on the highly pathogenic avian influenza ... See full document

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Distinct Pathogenesis of Hong Kong-Origin H5N1 Viruses in Mice Compared to That of Other Highly Pathogenic H5 Avian Influenza Viruses

Distinct Pathogenesis of Hong Kong-Origin H5N1 Viruses in Mice Compared to That of Other Highly Pathogenic H5 Avian Influenza Viruses

... avian influenza virus to cause pathological lesions in mice was the Eng/91 ...avian influenza virus strains has been known for some time (47), and data have indicated that the Eurasian lineage is more ... See full document

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Induction of neutralising antibodies by virus like particles harbouring surface proteins from highly pathogenic H5N1 and H7N1 influenza viruses

Induction of neutralising antibodies by virus like particles harbouring surface proteins from highly pathogenic H5N1 and H7N1 influenza viruses

... or H5-VLPs were concentrated and purified by ultra- centrifugation [19] before injection in BalbC ...different influenza strains, we generated H7-VLPs or H5- VLPs treated with a citrate buffer at ... See full document

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Characterization of a Highly Pathogenic H5N1 Avian Influenza A Virus Isolated from Duck Meat

Characterization of a Highly Pathogenic H5N1 Avian Influenza A Virus Isolated from Duck Meat

... different from the Hong Kong H5N1 viruses because at least four of the internal genes are different from all previously characterized ...several influenza viral genes have been ... See full document

12

First introduction of highly pathogenic H5N1 avian influenza A viruses in wild and domestic birds in Denmark, Northern Europe

First introduction of highly pathogenic H5N1 avian influenza A viruses in wild and domestic birds in Denmark, Northern Europe

... HAs from the Danish isolates were ...The viruses isolated from domestic birds, a peacock and a fowl, varied from the wild bird isolates in the HA protein with the substitutions R162I and I232V ... See full document

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NP Body Domain and PB2 Contribute to Increased Virulence of H5N1 Highly Pathogenic Avian Influenza Viruses in Chickens

NP Body Domain and PB2 Contribute to Increased Virulence of H5N1 Highly Pathogenic Avian Influenza Viruses in Chickens

... reassortant viruses using the reverse genetics method, MDCK and 293T cells were cocultured and transfected with 1 ␮g of each of the eight plasmids and 16 ␮l of Trans-IT-LT1 (Mirus Bio) in 200 ␮l of Opti-MEM ... See full document

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Detection of Mammalian Virulence Determinants in Highly Pathogenic Avian Influenza H5N1 Viruses: Multivariate Analysis of Published Data

Detection of Mammalian Virulence Determinants in Highly Pathogenic Avian Influenza H5N1 Viruses: Multivariate Analysis of Published Data

... HPAI H5N1 in mammals and to indicate possible interactions between the ...for H5N1 isolates with experimentally determined virulence in mammals and downloaded the corresponding full genome se- quences ... See full document

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PB2 Residue 158 Is a Pathogenic Determinant of Pandemic H1N1 and H5 Influenza A Viruses in Mice

PB2 Residue 158 Is a Pathogenic Determinant of Pandemic H1N1 and H5 Influenza A Viruses in Mice

... putative pathogenic determinants that were iden- tified in lethal plaque-picked variants selected after nine serial passages in BALB/c mice ...data from our study independently demon- strate that PB2 ... See full document

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Effect of species, breed and route of virus inoculation on the pathogenicity of H5N1 highly pathogenic influenza (HPAI) viruses in domestic ducks

Effect of species, breed and route of virus inoculation on the pathogenicity of H5N1 highly pathogenic influenza (HPAI) viruses in domestic ducks

... LPAI viruses, replication of the H5N1 HPAI viruses in ducks is primarily associated with the respiratory ...shed H5N1 HPAI virus via the cloacal and respiratory routes for many days ...with ... See full document

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Characterization of H5N1 influenza viruses isolated from humans in vitro

Characterization of H5N1 influenza viruses isolated from humans in vitro

... 1997 H5N1 viruses in inbred mice [10], although certain 1997 H5N1 viruses that lacked this substitution were also highly lethal for mice ...with low virulence, and also has PB2 ... See full document

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Characterization of a highly pathogenic H5N1 influenza virus derived from bar-headed geese in China

Characterization of a highly pathogenic H5N1 influenza virus derived from bar-headed geese in China

... swabs from bar-headed geese, great cormorants, great black-headed gulls, brown-headed gulls and ruddy shelducks that died during the 2005 HPAI outbreak at Qinghai Lake in ...(Bh H5N1 virus) was selected for ... See full document

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The Hemagglutinin Protein of Highly Pathogenic H5N1 Influenza Viruses Overcomes an Early Block in the Replication Cycle To Promote Productive Replication in Macrophages

The Hemagglutinin Protein of Highly Pathogenic H5N1 Influenza Viruses Overcomes an Early Block in the Replication Cycle To Promote Productive Replication in Macrophages

... of influenza viruses with mammalian alveolar and peritoneal macrophages demonstrated that infection is abortive, failing to yield infectious virus into the cellular supernatant (19, 20, ...seasonal ... See full document

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