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Characterization of two putative potassium channels in Plasmodium falciparum
... identify two putative K + channel genes (pfk1 and ...these putative K + chan- nel proteins, showing their differential expression and cel- lular localization in asexual blood stage ...only two ... See full document
11
Characterization of fine specificity of the immune response to a Plasmodium falciparum rhoptry neck protein, PfAARP
... Immunological characterization of potential blood-stage malaria antigens would be a valuable strat- egy in the development of an effective ...that Plasmodium falciparum apical asparagine- rich ... See full document
14
Biochemical characterization of the malaria parasite Plasmodium falciparum CLpB homologue PfClpB1 localized to the apicoplast
... 1.6 Hypothesis and objectives Previous studies localize PfClpB1 in the apicoplast of Plasmodium falciparum. The characterization of biochemical and structural properties of pfClpB1 have yet not been ... See full document
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Characterization of Two Putative Protein Translocation Components in the Apicoplast of Plasmodium falciparum
... The two other homologues are putatively ER- localized proteins, containing only signal peptide N termini: PfhDer1-1 (PF10_0317) and PfhDer1-2 (PF14_0653), where “h” denotes host of the endosymbiont, which, in this ... See full document
9
In Silico Structural Characterization of Plasmodium Falciparum Helicase, PfBrr2
... Department of Biotechnology, Guru Nanak Dev University, Amritsar, Punjab, India. http://dx.doi.org/10.13005/bbra/2657 (Received: 08 August 2018; accepted: 01 September 2018) Plasmodium falciparum is a ... See full document
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Characterization Of Protein Prenyltransferases And Protein Prenylation In Plasmodium Falciparum
... prenylation. Two of these peptides form an αβ heterodimer, similar other prenyltransferases, and a 95kDa protein known as Rab escort protein ...contains two unique domains, an IG-like domain and an LRR ... See full document
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Characterization of Plasmodium falciparum structure in Nigeria with malaria SNPs barcode
... Background: Plasmodium falciparum malaria remains a major health challenge in Nigeria despite the global decline of its incidence and mortality ...P. falciparum and controlling the spread of the ... See full document
10
Identification and characterization of DNA endonucleases in Plasmodium falciparum 3D7 clone
... Results: Of the seven proteins analysed, two proteins were not soluble. Fragments derived from the rest five endo- nuclease sequences were successfully expressed as soluble proteins, and which were used to ... See full document
10
Characterization of Plasmodium falciparum ATP dependent DNA helicase RuvB3
... P. falciparum RuvBs should be no exception. Analysis of P. falciparum genome database identifies at least three RuvB homologues, namely, PfRuvB1, PfRuvB2 and PfRuvB3 ... See full document
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Biochemical and functional characterization of Plasmodium falciparum DNA polymerase δ
... Conclusions Recombinant PfPolδ-cat, PfPolδS and PfPCNA1 were suc- cessfully expressed heterologously. PfPolδ-cat contains both DNA polymerase and 3 ′ –5 ′ exonuclease activity as found in the human counterpart. However, ... See full document
10
Biochemical and functional characterization of Plasmodium falciparum GTP cyclohydrolase I
... certain Plasmodium falciparum isolates can cause antifolate resistance and influence the course of antifolate resistance ...P. falciparum GCH1 in drug resistance ...P. falciparum GCH1 in terms ... See full document
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Characterization of antibodies to sporozoites in Plasmodium falciparum malaria and correlation with protection
... The antibody response to sporozoites of Plasmodium falciparum and the role of these antibodies in protection against malaria have not been systematically investigated.. An understanding [r] ... See full document
5
Characterization of T cell activation and regulation in children with asymptomatic Plasmodium falciparum infection
... P. falciparum infections, and the correlations between these and levels of ...P. falciparum-infected children were more responsive to iRBC stimulation compared to cells from symptomatic ... See full document
13
Discovery and characterization of a novel class of metabolic regulators in the malaria parasite Plasmodium falciparum
... cellular levels of isoprenoid precursor metabolites. Complementation of a deleterious PfHAD1 allele restores FSM sensitivity. These findings strongly support that the primary biochemical change responsible for these ... See full document
279
Characterization of Plasmodium falciparum and Plasmodium vivax recent exposure in an area of significantly decreased transmission intensity in Central Vietnam
... Methods: A 1‑year prospective cohort study (n = 429) was performed in three rural communities in Quang Nam province. Six malaria screenings were conducted between November 2014 and November 2015, including system‑ atic ... See full document
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Characterization of blood dendritic and regulatory T cells in asymptomatic adults with sub microscopic Plasmodium falciparum or Plasmodium vivax infection
... human Plasmodium infection studies, naïve volunteers experi- mentally infected with ...P. falciparum displayed reduced circulating pDC and mDC levels, followed by down- regulation of HLA-DR on the surface ... See full document
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Plasmodium vivax and Plasmodium falciparum ex vivo susceptibility to anti malarials and gene characterization in Rondônia, West Amazon, Brazil
... Discussion Due to the strong impact of chemo-resistance among the malaria parasites to most drugs used in the control of the disease, monitoring the development of resistant phenotypes and genotyping are priorities ... See full document
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Isolation, production and characterization of fully human monoclonal antibodies directed to Plasmodium falciparum MSP10
... Here, additional human antibodies specific for the merozoite surface, isolated by an innovative human antibody technology platform, are presented. This tech- nology combines the screening of naturally exposed semi-immune ... See full document
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Biological characterization of chemically diverse compounds targeting the Plasmodium falciparum coenzyme A synthesis pathway
... P. falciparum gametocytes was determined to assess stage-specificity and transmission-reducing ...of two compounds with sub-micromolar potencies across all intra-erythrocytic stages, activity against late ... See full document
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Genome wide identification and characterization of transfer RNA derived small RNAs in Plasmodium falciparum
... P. falciparum has restricted genome-wide small RNA ...that Plasmodium parasites complete gene expression regula- tion through molecules that can substitute for miRNAs, ... See full document
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