[PDF] Top 20 Characterization of a Single-Cycle Rabies Virus-Based Vaccine Vector
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Characterization of a Single-Cycle Rabies Virus-Based Vaccine Vector
... the virus undergoes one complete cycle of replication in the primary infected cell and produces progeny virions that are unable to spread to a second round of ...vaccinia virus (VV), canarypox ... See full document
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Rabies virus-based COVID-19 vaccine CORAVAX™ induces high levels of neutralizing antibodies against SARS-CoV-2.
... CORAVAX vaccine, we immunized groups of fi ve BALB/c mice with live 10 7 foci forming units (ffu) CORAVAX at day 0; 10 μ g inactivated CORAVAX or 10 μ g inactivated CORAVAX virions adjuvanted with MPLA- AddaVax at ... See full document
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Construction and Characterization of a Single-Cycle Chimeric Flavivirus Vaccine Candidate That Protects Mice against Lethal Challenge with Dengue Virus Type 2
... flavivirus vaccine technology based on a single-cycle, capsid (C) gene-deleted flavivirus called ...a single cycle of infection in vaccinated ...dengue vaccine by ... See full document
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The Nucleoprotein Is Required for Lymphocytic Choriomeningitis Virus-Based Vaccine Vector Immunogenicity
... of single-cycle infectious arenavirus vectors depends on robust viral mRNA transcription and genome replication and, thus, on de novo synthesis of the viral trans-acting factor ...arenavirus- based ... See full document
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Replicating Single-Cycle Adenovirus Vectors Generate Amplified Influenza Vaccine Responses
... RD-Ad vector infects a cell, it carries only one copy of an influenza virus antigen and expresses only “1 ⫻ ” ...more vaccine, which also increases the likelihood of side ...influenza vaccine ... See full document
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A Vesicular Stomatitis Virus-Based Hepatitis B Virus Vaccine Vector Provides Protection against Challenge in a Single Dose
... Construction and characterization of recombinant VSV ex- pressing HBV MS protein. The HBV middle surface (MS) envelope glycoprotein (ayw serotype) open reading frame was PCR amplified and cloned into a plasmid DNA ... See full document
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Genetic rearrangements occurring during a single cycle of murine leukemia virus vector replication: characterization and implications.
... a single parental vector pro- ...a single parental provirus were produced by (i) the transfection of GP1E-86 cells with vector plasmid pMSTK2 and selection in medium containing G418, (ii) ... See full document
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Second-Generation Rabies Virus-Based Vaccine Vectors Expressing Human Immunodeficiency Virus Type 1 Gag Have Greatly Reduced Pathogenicity but Are Highly Immunogenic
... the vector itself remains a concern for its use in ...a single surface glycoprotein, G, of RV is responsible for RV pathogenesis (6, 8, 20, 23, ...second-generation vaccine vectors by genetically ... See full document
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A New Rabies Vaccine Based on a Recombinant Orf Virus (Parapoxvirus) Expressing the Rabies Virus Glycoprotein
... as rabies vaccines for companion ani- mals. Various recombinant rabies vaccines have been generated using different viral vector systems, such as Newcastle disease vi- rus (22), Sindbis virus ... See full document
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A Novel Rabies Vaccine Based on a Recombinant Parainfluenza Virus 5 Expressing Rabies Virus Glycoprotein
... Parainfluenza virus type 5 (PIV5) is a nonsegmented negative- strand RNA virus with a genome of about 15 kb in size and belongs to the Paramyxovirus ...a single-dose inoculation of recombinant PIV5 ... See full document
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A Single-Cycle Vaccine Vector Based on Vesicular Stomatitis Virus Can Induce Immune Responses Comparable to Those Generated by a Replication-Competent Vector
... this single-cycle vector generates a much lower cellular immune response than the replication-compe- tent vector when given ...That vector induced weak immune responses to Env compared ... See full document
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The Rabies Virus Glycoprotein Receptor p75NTR Is Not Essential for Rabies Virus Infection
... mutant virus strains was performed in selection pressure conditions to prevent the growth of ...concentrated virus, the clarified supernatant was then loaded on a 25% glycerol cushion in TNE buffer (10 mM ... See full document
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B Cell Infection and Activation by Rabies Virus-Based Vaccines
... and virus. These include, most notably and classically, Epstein-Barr virus, which polyclonally in- fects B cells, resulting in broad B cell activation, antibody secre- tion, and lymphomagenesis ...the ... See full document
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Diagnosis and molecular characterization of rabies virus from a buffalo in China: a case report
... It has been reported that several amino acids in the RABV glycoprotein are responsible for pathogenicity [33,34]. Therefore, RABV glycoprotein is the best target protein to study virus-host interaction, or it may ... See full document
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Incidence of human rabies and characterization of rabies virus nucleoprotein gene in dogs in Fujian Province, Southeast China, 2002–2012
... of rabies virus anti- gens in canine saliva ...of rabies or ...the rabies virus vaccine strains are CTN, 3aG, PV and Flury in Fujian province, and veterinary vaccine ... See full document
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Effect of Passive Immunization or Maternally Transferred Immunity on the Antibody Response to a Genetic Vaccine to Rabies Virus
... riomeningitis virus (LCMV) causes tolerance of cytolytic T cells with concomitant activation of B cells, resulting in viral persistence ...eliminate vector-transfected cells or alternatively down-regulate ... See full document
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Construction and Characterization of a Hybrid Mouse Mammary Tumor Virus/Murine Leukemia Virus-Based Retroviral Vector
... (17) vector carrying the b-gal marker gene (cross-hatched box), the SV40 promoter driving expression from the neomycin resistance gene (checkered box), as well as the origin of replication (ori) from pBR322 ... See full document
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A Replication-Incompetent PB2-Knockout Influenza A Virus Vaccine Vector
... PB2-KO virus, pPolIPB2(120)GFP(120) and the remaining 7 PolI plasmids were cotrans- fected into 293T cells along with eukaryotic protein expression plasmids for PB2, PB1, PA, and NP derived from A/WSN/33 by use of ... See full document
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Hemagglutination by Rabies Virus
... Infectivity anid hemagglutinating activity mercaptoethanol Calbiochem, and dithioreitol of extracellular anid initracellular rabies viruses Calbiochem did not affect the HA, but the firs[r] ... See full document
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Characterization of an Experimental Vaccine for Bovine Respiratory Syncytial Virus
... Jenner Vector Core Facility, Oxford, United Kingdom) were used to detect protein-specific ...ELISA based on purified recombinant BRSV N expressed by ... See full document
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