[PDF] Top 20 Does Choice Matter? Reference Based Alignment for Molecular Epidemiology of Tuberculosis

... different reference genomes (Table 1 [21–27]; for divergence in average nucleotide identity, see Table S1 in the sup- plemental ...the reference or with a mapping quality of ⬍30 were ...each ... See full document

... M. tuberculosis isolates (Crofton and Mitchison, ...National Tuberculosis Control Programme (RNTCP) in India reports that two in five Indians are infected with latent TB (RNTCP report ...2009). ... See full document

... and molecular epidemiology methods allowed assessment of current trends and risk factors for subpopulation groups in Manitoba for contracting ...of tuberculosis elimination in ... See full document

... and molecular epidemiology (ME) methods in assessing tuberculosis (TB) transmission, comparing the popula- tions studied and the epidemiological links established by both ... See full document

... a molecular epidemiology study on 120 Mycobacterium tuberculosis isolates from patients presenting pulmonary tuberculosis (TB) in Burkina ...culture. Molecular analysis of specific ... See full document

... the molecular epidemiology and drug resistance of 121 Mycobacterium tuberculosis isolates from consecutive patients with culture-positive pulmonary tuberculosis attending a university hospital ... See full document

... of tuberculosis, recurrent tuberculosis is generally due to reactivation of the ...of tuberculosis reinfection increases in parallel with the incidence of disease and is likely to depend on the ... See full document

... Our molecular epidemiology study highlights some in- teresting epidemiological features of TB in Palermo and its province. The first is the wide heterogeneity of the MTBC strains detected in the years ... See full document

... ular and classical epidemiological methods. It was performed in Belgrade because it is the most densely populated urban area in central Serbia, with 1.6 million inhabitants, and has an incidence rate of TB comparable to ... See full document

... Nearly one-third (108 of 334 [32.3%]) of the cases of infec- tion in our study could be attributed to disease imported by asylum seekers. A small number of these cases (31 of 108 [28.7%]) could be diagnosed by screening ... See full document

... of molecular tools in combination with conventional epidemiological methods has proven to be indispensable to highlight the TB transmission dynamics and the emergence of new strains due to transcontinental ... See full document

... Several bio-climatic factors happened to appear as signifi- cant risk factors for the emergence of bTB. The annual ampli- tude of the temperature on the earth’s surface would be a risk factor, as shown for both ... See full document

... Our study also found that the proportion of resistance to anti-TB drugs within Beijing strains family was significantly higher than non-Beijing strains family.. This is consistent with p[r] ... See full document

... unfortunately, based on the 2015 WHO report in some countries such as South Africa, Mozambique, Indonesia and Cambodia the rate of disease was more than 350 in one hundred thousand ... See full document

... of tuberculosis has ...detailed tuberculosis surveillance in Norway is possible due to the small population size and low incidence of ...of tuberculosis surveillance, effective treatment, and contact ... See full document

... The higher levels of clustering in patients living in south London was not accounted for by controlling for other factors. We were unable to control ad- equately for social deprivation as information on unemployment or ... See full document

... of Epidemiology, Statens ...TB epidemiology, in a unique position because the bacteriological diagnostic service facility is centralized at one location, Statens Seruminstitut, where ... See full document

... Mycobacterium tuberculosis isolates among patients from Sweden was determined by a combination of two PCR-based techniques (spoligotyping and variable number of tandem repeats ...with tuberculosis ... See full document

... Few studies performed in developing countries have com- bined conventional and molecular epidemiology. Our study, conducted in a country with very high TB and HIV preva- lences, found that 42% of adult ... See full document

... M. tuberculosis population including SITs commonly distrib- uted worldwide (SIT50 and SIT53) and those with high spec- ificity for Turkey and its neighboring countries (SIT41 and SIT284), as well a smaller ... See full document