[PDF] Top 20 Claudin-6 and Claudin-9 Function as Additional Coreceptors for Hepatitis C Virus
Has 10000 "Claudin-6 and Claudin-9 Function as Additional Coreceptors for Hepatitis C Virus" found on our website. Below are the top 20 most common "Claudin-6 and Claudin-9 Function as Additional Coreceptors for Hepatitis C Virus".
Claudin-6 and Claudin-9 Function as Additional Coreceptors for Hepatitis C Virus
... Identification of CLDN6 and CLDN9 as HCV coreceptors. To test whether the newly identified HCV coreceptor CLDN1 is involved in HCV infection of all susceptible cell lines, the association between HCVpp ... See full document
7
Hepatitis C Virus Induces CD81 and Claudin-1 Endocytosis
... Silencing claudin-1 expression had no detectable effect on anti- body-primed CD81 endocytosis, demonstrating that claudin-1 ex- pression alone does not regulate CD81 ...active claudin-6 or ... See full document
12
Involvement of claudin 7 in HIV infection of CD4( ) cells
... -gp160 function of the ...-Env(-)-EGFP virus prepared from an oral epithelial cell line derived from a ...laboratory. C) Infection of the LNCaP and HeLa-CD4 cell lines by HIV at various ... See full document
12
Hepatoma Cell Density Promotes Claudin-1 and Scavenger Receptor BI Expression and Hepatitis C Virus Internalization
... To further dissect the role(s) of CLDN1 and SR-BI in cell contact-mediated modulation of HCV entry, we studied HCVcc internalization in subconfluent Huh-7.5 cells trans- duced to overexpress CLDN1 or SR-BI. Cells ... See full document
8
Monoclonal Antibodies against Extracellular Domains of Claudin-1 Block Hepatitis C Virus Infection in a Mouse Model
... protein (GFP) in the nucleus (Huh7.5.1-8/GFP-Nuc cells) were estab- lished via the transfection of pAcFP1-Nuc (TaKaRa Bio Inc.) into Huh7.5.1-8 cells. Human embryonic kidney 293T cells and human fibro- sarcoma HT1080 ... See full document
14
Mouse-Specific Residues of Claudin-1 Limit Hepatitis C Virus Genotype 2a Infection in a Human Hepatocyte Cell Line
... the virus encountering first SR-BI and CD81 and subsequently ...entry function in ...SR-BI function in HCV entry is, to some extent, species specific ... See full document
12
Novel Function of CD81 in Controlling Hepatitis C Virus Replication
... shown in Fig. 4D and 6A, CD81-L2 cells showed decreasing HCV RNA levels after HCV RNA transfection, suggesting a lack of efficient HCV RNA replication. In contrast, following CD81 DNA transfection, CD81-L2 cells showed ... See full document
12
Sec24C-Dependent Transport of Claudin-1 Regulates Hepatitis C Virus Entry
... the C-terminal cytoplasmic tails from 27 members of CLDN family proteins revealed that there is a conserved YV motif within the carboxy terminus of several claudins ...with claudin-1, claudin-4, ... See full document
19
Identification of Piperazinylbenzenesulfonamides as New Inhibitors of Claudin-1 Trafficking and Hepatitis C Virus Entry
... Activation of the PKA pathway by either forskolin treatment, overexpression of the exogenous GPCR 5-HT6, or overexpression of the PKA catalytic subunit itself increased CLDN1 export at the surface or rescued its surface ... See full document
19
Functional Analysis of Claudin-6 and Claudin-9 as Entry Factors for Hepatitis C Virus Infection of Human Hepatocytes by Using Monoclonal Antibodies
... CLDNs are critical components of tight junctions (TJ) and regulate paracellular permeability and polarity. The CLDN super- family comprises more than 20 members that are expressed in a tissue-specific manner. CLDN1 is an ... See full document
6
The Tight Junction Proteins Claudin-1, -6, and -9 Are Entry Cofactors for Hepatitis C Virus
... against claudin-1 (1:500), 12H12 monoclonal antibody (MAb) against claudin-2 (1:500), and 3E2C1 MAb against claudin-4 (1:500) and Santa Cruz antibodies C20 goat polyclonal antibody against ... See full document
6
A New Explanation of Inflammation in Rheumatoid Arthritis Patients With Respect to Claudin-5, Matrix Metalloproteinase-9, and Neuroserpin
... because tPA can also activate MMPs, we should also consider that an increase in NSP observed between RA patients and HS may involve MMP-9, albeit directly or indirectly (via inflammation- associated mechanisms). ... See full document
7
Disease associated mutations affect intracellular traffic and paracellular Mg2+ transport function of Claudin 16
... Interestingly, Cldn16 can internalize via a clathrin-mediated pathway. Similar to WT Cldn16, mutants transported to the cell surface were detected in small vesicles positive for the early endo- some marker EEA1. Since ... See full document
15
Clinicopathologic significance of claudin-6, occludin, and matrix metalloproteinases −2 expression in ovarian carcinoma
... of claudin-6 in 36 ovarian papillary serous carcinomas is significantly higher than in 26 ovarian serous adenomas; claudin-6 expression in metastatic tumors was significantly higher than in ... See full document
8
Murine mammary tumor cells with a claudin-low genotype
... of claudin-low tumors (MDA-MB- 435, MDA-MB-436, Hs578T, BT549, MDA-MB-231, MDA-MB-157, SUM1315MO2, SUM159PT and HBL100), fewer claudin-low, murine mammary tumor cell lines have been established ...where ... See full document
6
Clinicopathological significance of claudin 4 in gastric carcinoma
... analysis, claudin protein expression was not associated with patients’ CSS (P = ...of claudin-4 in expanding and infiltrative type gastric ...of claudin-4 was significantly better compared to those ... See full document
9
The Role of Claudin-5 on Xenopus Heart Development
... 2005). Compare with other factors such as noggin, chd can gain detectable dorsalizing and neutralizing activity in lower amount and has much stronger blocking function for BMP4 (Piccolo, 1996). Except for dorsal ... See full document
87
The claudin family of proteins in human malignancy: a clinical perspective
... occludin, claudin, and junctional adhesion molecule ...in claudin expression observed in various cancers and their mechanisms of ...of claudin expression, the barrier function of the cancerous ... See full document
9
Claudin 6, 10d and 10e contribute to seawater acclimation in the euryhaline puffer fish Tetraodon nigroviridis
... physiological function is poorly ...(Figs 6, 7). It is also noteworthy that in T. nigroviridis skin, Cldn-6 co-localized with NKA-ir cells, suggesting that there may be some role for skin TJ proteins ... See full document
10
Original Article Identification of claudin-2, -6, -11 and -14 as prognostic markers in human breast carcinoma
... (EMT) [42, 43]. However, downregulation of cer- tain claudins in tumors is accompanied by the interruption of TJs during tumorigenesis and EMT [44, 45]. Furthermore, enforced initiation of EMT in epithelial cells leads ... See full document
10
Related subjects