[PDF] Top 20 Clostridium difficile is among the most common hospital-associated
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Clostridium difficile is among the most common hospital-associated
... lostridium difficile is among the most common hospital-asso- ciated infections, causing gastrointestinal disease which ranges from mild diarrhea to toxic megacolon, sepsis, and death; ... See full document
10
Clostridium difficile infection in an Iranian hospital
... was associated with older ...to most other reports [1,18] and less than 30% of CDI patients were over the age of ...very common in both CDI and non-CDI groups, and the role of antimicrobials in CDI ... See full document
5
Economic Evaluation of Laboratory Testing Strategies for Hospital Associated Clostridium difficile Infection
... C. difficile if not isolated (45, 46, ...C. difficile that causes diarrhea than for C. difficile as a mere colonizer (42, ...C. difficile), our model may relatively overestimate the cost of a ... See full document
8
The epidemiology of Clostridium difficile infection in Australia
... C. difficile colonized pa- tients using multiple-locus variable number tandem repeat ...from hospital- associated CDI cases were highly related to isolates from asymptomatic ...C. difficile ... See full document
229
High Throughput Analysis of Gene Essentiality and Sporulation in Clostridium difficile
... ABSTRACT Clostridium difficile is the most common cause of antibiotic-associated intestinal infections and a significant cause of morbidity and ...C. difficile requires ... See full document
13
Risk factors, course and outcome of Clostridium difficile infections
... academic hospital, recent abdominal surgery, the prior use of antibiotic agents, diarrhoea as a reason for admission and hypotension were significantly associated with a complicated course of CDI after 30 ... See full document
211
Comparison of pediatric and adult antibiotic-associated diarrhea and Clostridium difficile infections
... more common in children, while most cases of adult CDI are associated with healthcare ...of hospital exposures, disruptive medications, ... See full document
28
Association of Clostridium difficile with Antibiotic Associated Diarrhea among Hospitalized Children in Diyala Iraq
... Clostridium difficile is an anaerobic, spore-forming, and toxin-producing bacil- lus that emerged as an important cause of antibiotic-associated diarrhea world- wide [1] [2] ...Cl. difficile ... See full document
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Comparative Analysis of Prevalence, Risk Factors, and Molecular Epidemiology of Antibiotic Associated Diarrhea Due to Clostridium difficile, Clostridium perfringens, and Staphylococcus aureus
... for Clostridium difficile, Clostridium perfringens, and Staphylococcus aureus antibiotic-associated diarrhea ...C. difficile cytotoxin, ...C. difficile cytotoxin, ...a ... See full document
7
Cost of hospital management of Clostridium difficile infection in United States—a meta analysis and modelling study
... In this study, we only assessed the quality of study em- phasizing statistical methods and did not use the modified economic evaluation guideline as other COI systematic re- views. Cost and LOS estimation of ... See full document
18
Clostridium difficile infections in teaching hospital in northern Finland
... C. difficile infection (CDI) have typic- ally been recent antibiotic exposure, advanced age, use of proton pump inhibitor, length of stay in healthcare settings, serious underlying illness, and immunocom- promised ... See full document
5
Quality of life and utility decrement associated with Clostridium difficile infection in a French hospital setting
... Another aspect that makes these evaluations difficult is that CDIs analogous to other clinical states with diar- rhea are transient. This feature is important to consider in all studies performed by interviewing a sample ... See full document
7
Clostridium difficile infection health disparities by race among hospitalized adults in the United States, 2001 to 2010
... for hospital LOS, which allowed us to cen- sor those CDI patients who died in the ...region, hospital size, hospital ownership, other infectious diseases as in- dicated by ICD-9-CM codes (skin ... See full document
7
Molecular Epidemiology of Hospital Associated and Community Acquired Clostridium difficile Infection in a Swedish County
... C. difficile and typing of isolates according to the recently developed reference method PCR ribotyping ...C. difficile have been used and evaluated, and PCR ribotyping has emerged as superior with regard ... See full document
9
Pathogenicity Locus, Core Genome, and Accessory Gene Contributions to Clostridium difficile Virulence
... patients hospital- ized at Memorial Sloan Kettering Cancer Center (MSKCC) and Barnes-Jewish Hospital, infected mice with these ...variants associated with viru- ... See full document
15
Risk factors for Clostridium difficile infection in surgical patients hospitalized in a tertiary hospital in Belgrade, Serbia: a case–control study
... C. difficile to colonize and overgrow within the gastrointestinal ...the most important RF for CID in Quebec during an epidemic caused by a hipervirulent strain of ...was associated with a decline in ... See full document
6
Isolation and characterization of Clostridium difficile and toxin detection from faecal specimens in patients with Antibiotic associated diarrhea in a tertiary care centre
... C. difficile is a major cause of antibiotic associated diarrhea and accounts for about 15-25% of cases ...C. difficile has overtaken methicillin resistant Staphylococcus aureus (MRSA) as the ... See full document
115
Antibiotic susceptibility of Clostridium difficile is similar worldwide over two decades despite widespread use of broad spectrum antibiotics: an analysis done at the University Hospital of Zurich
... We wondered whether certain anti-infective drugs were over-represented in our patient cohort and, thus, prefer- entially associated with CDI. We compared the antimicro- bial usage of our patient cohort to the ... See full document
9
Intrinsic Toxin Derived Peptides Destabilize and Inactivate Clostridium difficile TcdB
... ABSTRACT Clostridium difficile infection (CDI) is a major cause of hospital-associated, antibiotic-induced diarrhea, which is largely mediated by the production of two large multidomain clostridial ... See full document
13
Microbiome Data Distinguish Patients with Clostridium difficile Infection and Non C difficile Associated Diarrhea from Healthy Controls
... Michigan Hospital, Ann Arbor, ...C. difficile using the ...C. difficile antigen glutamate dehydrogenase (GDH) and the C. difficile toxin proteins A and ...C. difficile tcdB gene, which ... See full document
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