[PDF] Top 20 Conformational changes in Sindbis virus envelope proteins accompanying exposure to low pH.
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Conformational changes in Sindbis virus envelope proteins accompanying exposure to low pH.
... 45, 1983 SINDBIS VIRUS PROTEIN CONFORMATIONAL CHANGES 1095 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest changes described above in physical properties cannot induce [r] ... See full document
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Conformational Changes, Plasma Membrane Penetration, and Infection by Human Rhinovirus Type 2: Role of Receptors and Low pH
... that low-pH-induced structural changes oc- cur to a similar extent at 34 and 4°C ...membrane-bound virus but in the absence of internalization, whether the low pH and any of the ... See full document
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Site-Directed Antibodies against the Stem Region Reveal Low pH-Induced Conformational Changes of the Semliki Forest Virus Fusion Protein
... dengue virus is specifically blocked by the addition of exogenous domain III during the low pH-triggering step ...the exposure of the MAb E1a-1 epitope, suggesting that before the folding-back ... See full document
9
Low-pH conformational changes of rabies virus glycoprotein and their role in membrane fusion.
... This effect on the fusion curves was still observed when the virus was preincubated with liposomes at pH 6.7 and 0°C data not shown, whereas a preincubation at pH 7.3 and 0°C did not mod[r] ... See full document
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Low-pH-Dependent Fusion of Sindbis Virus with Receptor-Free Cholesterol- and Sphingolipid-Containing Liposomes
... neutral pH, mediated by interaction of the viral spike with its cellular ...the pH of endosomes, as evidenced by the translation of viral RNA in the cell cytosol (7, ...detected conformational ... See full document
9
The Surface Conformation of Sindbis Virus Glycoproteins E1 and E2 at Neutral and Low pH, as Determined by Mass Spectrometry-Based Mapping
... of virus glycoproteins with host cells during attachment and ...the virus glycoproteins are not required to change po- sition in the envelope, a difficult process considering the mul- tiple protein ... See full document
12
Structural Changes in Influenza Virus at Low pH Characterized by Cryo-Electron Tomography
... Influenza virus enters host cells by endocytosis. The low pH of endosomes triggers conformational changes in hemagglutinin (HA) that mediate fusion of the viral and endosomal ...A ... See full document
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Identification of amino acids controlling the low-pH-induced conformational change of rabies virus glycoprotein.
... surface or after detergent solubilization with equal efficiency but recognized only the I conformation of G on the viral surface (21, 28). These antibodies became neutralizing when the virions were preincubated at ... See full document
8
Structural Basis of Local, pH-Dependent Conformational Changes in Glycoprotein B from Herpes Simplex Virus Type 1
... of pH on the biochemical properties of ...global pH-dependent changes either in crystals or in solution, as seen by EM and size exclusion ...Nevertheless, low-pH-treated gB has a faster ... See full document
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Placement of the Structural Proteins in Sindbis Virus
... at low pH to permit the exposure of viral membrane in the middle of each spike during fusion, as suggested by Kuhn et ...suggested conformational changes as probed by pro- teolytic ... See full document
14
Receptor-Induced Conformational Changes in the SU Subunit of the Avian Sarcoma/Leukosis Virus A Envelope Protein: Implications for Fusion Activation
... of low pH on the SU-A/sTva complex. Application of a low-pH pulse to the SU-A/sTva complex did not significantly alter its structure as measured by CD ...irreversible low-pH ... See full document
12
Conformational Changes in Sindbis Virus Induced by Decreased pH Are Revealed by Small-Angle Neutron Scattering
... of Sindbis virus at pH ...large conformational changes of the glycoprotein coat of the virus ...particle. Exposure of virus to pH ...neutral pH, which ... See full document
6
Structure-based identification of an inducer of the low-pH conformational change in the influenza virus hemagglutinin: irreversible inhibition of infectivity.
... the pH range over which C22 inhibits hemolysis most effectively, pH ...rapid conformational change in HA which inactivates HA, thereby depleting the pool of fusion-active trimers and inhibiting fu- ... See full document
13
Oligomeric rearrangement of tick-borne encephalitis virus envelope proteins induced by an acidic pH.
... flavivirus envelope protein E undergoes irreversible conformational changes at a mildly acidic pH which are believed to be necessary for membrane fusion in ...the envelope ... See full document
6
Sindbis Virus Conformational Changes Induced by a Neutralizing Anti-E1 Monoclonal Antibody
... the virus E1 glycoprotein (6, 34, 35) to produce a conformationally neutralized ...major conformational changes seen in reconstructions of low-pH-treated virus, a treatment which ... See full document
11
Two-Step Conformational Changes in a Coronavirus Envelope Glycoprotein Mediated by Receptor Binding and Proteolysis
... leukosis virus (ASLV) envelope protein, Env ...receptor-induced conformational changes in Env at neutral pH. The changes lead to exposure of the fusion peptide so that Env ... See full document
9
Low pH-Induced Conformational Change in Herpes Simplex Virus Glycoprotein B
... Acid pH alters the conformation of a soluble, recombinant form of ...far, pH-triggered changes have been detected in virion gB in the context of the HSV envelope, which includes the other ... See full document
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Structural requirements for low-pH-induced rearrangements in the envelope glycoprotein of tick-borne encephalitis virus.
... reversible changes, sE dimers and full-length E dimers were treated with MES buffer to yield a final pH of ...at low pH lasted only 10 min, the low-pH-treated full-length E ... See full document
6
Isolation and Purification of the Envelope Proteins of Newcastle Disease Virus
... It was found in the could only be obtained if Triton treatment present studies that neither this non-glycosylwas done in the presence of 1 M KCI, whereas ated protein nor the smaller NDV[r] ... See full document
9
Conformational changes in natural biopolymers induced by electromagnetic field and cadmium ion exposure
... the low- frequency EMF influence could be the production of reactive oxygen species in ...and low-frequency EMF exposure [22]. Thus, combined exposure of DNA molecules to EMF and cadmium ions ... See full document
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