[PDF] Top 20 Control of oligodendroglial cell number by the miR 17 92 cluster
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Control of oligodendroglial cell number by the miR 17 92 cluster
... prevents cell death ...whether miR-17-19b is able to rescue oligodendrocytes from apoptosis, miR-17-19b precursors were expressed in OPCs before growth factor ...by ... See full document
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Upregulation of the miR-17-92 cluster and its two paraloga in osteosarcoma - reasons and consequences
... The miR-17-92 cluster, also named oncomir-I, and its two paraloga miR-106a-363 and miR-106b-25 were among the first families of those small RNA molecules that were found to be ... See full document
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miR 17 92 expression in differentiated T cells implications for cancer immunotherapy
... of miR-17-92 cluster members in the human Jurkat T cell line confers increased IL-2 production and resistance to ...1) control vector encoding GFP; 2) the 17-92-1 ... See full document
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The Role of Myc and the miR 17~92 Cluster in Histone Deacetylase Inhibitor Induced Apoptosis of Solid Tumors
... fibroblast cell line model, Jiang et ...induced cell death ...cancer cell lines including 3 breast cancer (MCF-7, MDA-MB-231, and AU565), 5 lung cancer (H460, Calu-6, A549, H1975, and H1792), two ... See full document
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Short stature, digit anomalies and dysmorphic facial features are associated with the duplication of miR-17 ~ 92 cluster
... post-transcriptional control of gene expres- sion by binding to complementary sites within target mRNAs, thereby mediating their degradation or repres- sing translation ...the miR-17 ~ 92 ... See full document
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Regulation of endoderm formation and left right asymmetry by miR 92 during early zebrafish development
... the miR-17-92 cluster significantly accelerated disease onset and progression (He et ...the miR-17-92 cluster is directly regulated by c-Myc and E2F3 (O’Donnell et ... See full document
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A functional polymorphism in the promoter of miR-17-92 cluster is associated with decreased risk of ischemic stroke
... Continuous variables (TG, LDL-C, HDL-C and TCH) were displayed as mean ± SD, and if the data is normally distrib- uted, Student’s t-test was used; otherwise, rank-sum test was used. Categorical variables (age, gender, ... See full document
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C-Myc-dependent repression of two oncogenic miRNA clusters contributes to triptolide-induced cell death in hepatocellular carcinoma cells
... The complementary DNA encoding ERCC3 and c-Myc was PCR-amplified by the Pfu Ultra II Fusion HS DNA Polymerase (Agilent Technologies, Palo Alto, CA), and was subcloned into the pcDNA3.1 vector (Invitrogen, Carlsbad, CA). ... See full document
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The other face of miR-17-92a cluster, exhibiting tumor suppressor effects in prostate cancer
... of miR-17-92a cluster in prostate cancer cells altered cellular morphology and reduced expression of the putative target ...expressing miR-17-92a cluster miRNAs or Scr ...PC-3 ... See full document
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The MYC /miR-17-92 axis in lymphoproliferative disorders: A common pathway with therapeutic potential
... induced miR-17-92 overexpression in lymphocytes developed an aggressive lymphoproliferative disorder associated with autoimmunity followed by a premature ...the miR-17-92 ... See full document
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miR-302 cluster inhibits angiogenesis and growth of K562 leukemia cells by targeting VEGFA
... of miR-302 cluster in CML, miR-302 cluster mimics or miRNA negative control was transfected into K562 ...of miR-302 cluster were significantly upregulated ...negative ... See full document
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<p>Long Non-Coding RNA PVT1 Regulates BAMBI To Promote Tumor Progression In Non-Small Cell Lung Cancer By Sponging miR-17-5p</p>
... of miR- 17-5p often associates with cancer ...of miR-17-5p was signi fi cantly decreased in triple-negative breast cancer tissues and ...that miR-17-5p was conspicuously reduced ... See full document
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Targeting of HER3 with Functional Cooperative miRNAs Enhances Therapeutic Activity in HER2-Overexpressing Breast Cancer Cells
... non-small cell lung cancer [40, ...non-small cell lung cancer ...of miR-125a, miR-125b, and miR-205, all of which were reported to directly target the 3’UTR of erbB3 mRNA [35, 36], and ... See full document
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Expression of miR-17-92 enhances anti-tumor activity of T-cells transduced with the anti-EGFRvIII chimeric antigen receptor in mice bearing human GBM xenografts
... Therapy of mice bearing intracranial glioma xenografts 5- to 6-week-old NOD/Shi-scid,IL-2Rr KO Jic (NOG) fe- male mice (Jackson Laboratory, Bar Harbor, ME) were used in the experiments. Animals were handled in the Animal ... See full document
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Prognostic value of miR-17-5p in cancers: a meta-analysis
... high miR-17-5p expression was not the same across studies; thus, it was difficult to define miR-17-5p overexpres- sion in various ...high miR-17-5p ... See full document
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Cell number control and timing in animal development: the oligodendrocyte cell lineage
... to cell-cycle withdrawal and differentiation, raising the possi- bility that the increase in p27 is part of the effector mechanism that stops the cell ... See full document
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Original Article miRNA-17 promotes nasopharyngeal carcinoma radioresistance by targeting PTEN/AKT
... whether miR-17-5p was involved in cell proliferation regulation and examined the cell cycles of NPC cells with different treat- ...the cell cycle of the NPC cells was blocked at the ... See full document
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MiRNA-145 increases therapeutic sensibility to gemcitabine treatment of pancreatic adenocarcinoma cells
... Stable cell lines over-expressing miR-145 or negative control miRNA (miR-NC) were established using lentivirus carrying miR-145 or miR-NC, and verified by detecting the ... See full document
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Original Article miR-27a promotes cell proliferation and metastasis in renal cell carcinoma
... Abstract: miR-27a has been reported to exhibit abnormal expression in renal cell carcinoma (RCC), but the role of miR-27a in RCC remains ...of miR-27a was validated by Real-time PCR analysis ... See full document
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Original Article MicroRNA-126 regulates migration and invasion of gastric cancer by targeting CADM1
... that miR-126 expression was neg- atively correlated to CADM1, which was of sta- tistical ...high miR-126 expression had short DFS while those with low miR-126 expres- sion had long DFS, although the ... See full document
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