[PDF] Top 20 Effect of Ethanol on Monocytic Function in Human Immunodeficiency Virus Type 1 Infection
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Effect of Ethanol on Monocytic Function in Human Immunodeficiency Virus Type 1 Infection
... after ethanol, acetalde- hyde, and acetate in response to mitogens, MAb 446, and TT could be restored with the addition of exogenous IL-1a or IL-1b and anti-TGF-b ...antibodies. Ethanol, acetaldehyde, and ... See full document
9
Expression and Function of Chemokine Receptors on Human Thymocytes: Implications for Infection by Human Immunodeficiency Virus Type 1
... HIV-1 infection. A moderate frac- tion of SCID-hu-derived human thymocytes expressed CCR4 (16%) and CCR7 (11%), while a large fraction expressed CXCR4 ... See full document
9
Cell-Type-Dependent Effect of Transforming Growth Factor β, a Major Cytokine in Breast Milk, on Human Immunodeficiency Virus Type 1 Infection of Mammary Epithelial MCF-7 Cells or Macrophages
... pGL-HIV- 1-LTR ⌬ SP1, respectively ...the human T-cell leukemia virus type I (HTLV-I) LTR promoter followed by the luciferase gene ...Reagents. Human lactoferrin were purchased from ... See full document
7
Human Immunodeficiency Virus Induces a Dual Regulation of Bcl-2, Resulting in Persistent Infection of CD4+ T- or Monocytic Cell Lines
... HIV infection induces oxidative stress which initiates apoptosis by degradation of all the antioxidant systems including Bcl-2, except when this deg- radation is compensated for by an induction of Bcl-2 ...of ... See full document
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A Quantitative Measurement of Antiviral Activity of Anti-Human Immunodeficiency Virus Type 1 Drugs against Simian Immunodeficiency Virus Infection: Dose-Response Curve Slope Strongly Influences Class-Specific Inhibitory Potential
... HIV-1 infection in humans (23, 32), each drug class showed a characteristic slope value for inhibition of SIV infection ...SIV infection, and the slopes are shown as zero ...median ... See full document
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Lentivirus-Specific Cytotoxic T-Lymphocyte Responses Are Rapidly Lost in Thymectomized Cats Infected with Feline Immunodeficiency Virus
... example, immunodeficiency-causing lentiviruses, such as human immunodeficiency virus type 1 (HIV-1), simian immunodeficiency virus, and feline immuno- ... See full document
6
Stable human immunodeficiency virus type 1 (HIV-1) resistance in transformed CD4+ monocytic cells treated with multitargeting HIV-1 antisense sequences incorporated into U1 snRNA.
... The effect of U1/HIV antisense con- structs on Tat-activated expression was determined in transient expression assays measuring Tat-activated expression of CAT (see Materials and ... See full document
7
Inhibition of Lysosome and Proteasome Function Enhances Human Immunodeficiency Virus Type 1 Infection
... for 1 h and analyzed by flow cytometry 36 to 48 h after infection as we have previously described ...0.1, 1, 10, or 100 ng/ml (AnorMED; obtained through the NIH AIDS Research and Reference Reagent ... See full document
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Phagocytic Activity in Human Immunodeficiency Virus Type 1 Infection
... in human monocytes infected with wild-type strains of HIV-1, but not with nef gene- defective HIV-1 strains, confirming the role of this gene prod- uct in macrophagic cell inhibitory ...PMNL ... See full document
7
Natural Killer Cell Function Is Well Preserved in Asymptomatic Human Immunodeficiency Virus Type 2 (HIV-2) Infection but Similar to That of HIV-1 Infection When CD4 T-Cell Counts Fall
... Subject population. Subjects were selected from a clinic-based cohort of HIV- infected subjects at the MRC Laboratories in Fajara, The Gambia (30). These subjects included blood donors, female sex workers, cases of ... See full document
10
Human immunodeficiency virus type 1 coreceptors participate in postentry stages in the virus replication cycle and function in simian immunodeficiency virus infection.
... the human allele of the HIV-1 ...to infection by T-tropic HIV-1 isolates, and the sMAGI-CCR-5 cell line was susceptible to infection by M-tropic HIV-1 ...to infection by ... See full document
8
Evidence for an Activation Domain at the Amino Terminus of Simian Immunodeficiency Virus Vpx
... the infection of type I IFN-induced MDM, we compared the effect of wild-type, ⌬ vpx, Q76A-containing, and R22X chi- mera-containing VLP on HIV-1 infection of type I IFN- ... See full document
10
Transmission of Simian Immunodeficiency Virus SIVcpz and the Evolution of Infection in the Presence and Absence of Concurrent Human Immunodeficiency Virus Type 1 Infection in Chimpanzees
... after infection, the subsets returned to preinfection ...SIVcpz infection of chimpanzees and HIV-1 infection of humans appears to be related to mechanisms which allow chimpanzees to maintain ... See full document
11
Functional Redundancy in HIV-1 Viral Particle Assembly
... The reason for this NA requirement is not clear. However, chimeric proteins in which the nucleocapsid (NC) domain (the primary RNA-binding domain of the Gag protein) is replaced with a leucine-zipper dimerization domain ... See full document
6
Potent and Broad Neutralization of HIV-1 Subtype C by Plasma Antibodies Targeting a Quaternary Epitope Including Residues in the V2 Loop
... exceeding 1:10,000) by a single mutation in the FN/LRD-K-K ...The effect of the V1 loop in modulating neutralization sensitivity may be medi- ated through shielding of the neutralization epitope; however, ... See full document
14
HIV Diversity and Classification, Role in Transmission
... the virus will con- tinue to appear as long as the different subtypes of HIV-1 continue to circulate between continents and recombina- tion continues to ... See full document
11
HIV Diagnosis in Resource Constrained Setting: How Good Is the Current Algorithm?
... A retrospective analysis of data was carried out for a period of five years from 2008 to 2012 after obtaining in- stitutional ethics committee approval. All patients/clients including direct walk in clients, patients ... See full document
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Effects of Mutations in the G Tract of the Human Immunodeficiency Virus Type 1 Polypurine Tract on Virus Replication and RNase H Cleavage
... bound nucleic acid structure that may be important is an un- usual sugar switch on the second sugar in the RNA strand from a C3 ⬘ -endo sugar to a C2 ⬘ -endo sugar (this corresponds to the 5 ⬘ end of the PPT); it was ... See full document
10
Tat independent replication of human immunodeficiency viruses
... The replication of human immunodeficiency retroviruses involves a complex series of events that is regulated at both transcriptional and posttranscriptional levels. The tat gene product is a potent ... See full document
6
Effect of semen and seminal amyloid on vaginal transmission of simian immunodeficiency virus
... productive virus infection was assessed by measuring plasma viral RNA loads at weekly ...acute infection were about 6-fold higher after exposure to SP- and SEVI-treated ...Overall infection ... See full document
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