[PDF] Top 20 Effect of Randia Dumetorum Lam on Clonidine and Haloperidol-Induced Catalepsy in Mice

... perphenazine-induced catalepsy and suggested that anticholinergic activity of antidepressant might be due to an increase in dopamine content in brain or their ability to inhibit release of acetylcholine 14 ... See full document

... of mice to various extracts of Momordica dioica measured using a bar test, was enhanced by subcutaneous pretreatment with Clonidine (1 ...inhibited clonidine-induced catalepsy as ... See full document

... In clonidine induced catalepsy, hydroalcoholic extract reduces histamine content ...inhibitory effect on release of calcium from an intra cellular store of mast cells 23, 24 and stabilization ... See full document

... posture. Catalepsy is a sign of extrapyramidal effect of drugs that inhibit dopaminergic transmission or increase histamine release in ...brain. Clonidine, a ∝ 2 -adrenoceptor agonist, induces dose ... See full document

... using clonidine-induced catalepsy and haloperidol-induced catalepsy in Swiss albino mice at the dose of 50 mg/kg, ...inhibited clonidine- induced ... See full document

... the effect aqueous extracts of Phyllanthus maderaspatensis ...on clonidine-induced catalepsy, as it is used traditionally in the treatment of ...Since catalepsy is a common extra- ... See full document

... Catalepsy is a condition in which the animal is not able to correct an externally imposed ...anticataleptic effect of methanolic extract of roots of Calotropis gigantea ...in clonidine and ... See full document

... cataleptic effect of clonidine in the mice is mediated by histamine release from mast cells, and the clonidine-induced catalepsy was potentiated by residue and synthetic ...The ... See full document

... of clonidine and haloperidol-induced catalepsy in mice potentially Aqueous extract of Momordica dioica pulp showed most potent inhibition of clonidine-induced ... See full document

... the effect of yctanthes arbortristis bark on clonidine-induced catalepsy, as it is used traditionally in the treatment of ...Since catalepsy is a common extra-pyramidal side ... See full document

... of Randia dumetorum fruit extract have shown that it contains oleonolic acid 3- ...of Randia dumetorum may be responsible for exerting beneficial ... See full document

... seizures induced by maximum electroshock and also inhibited seizures induced by pentylenetetrazole, electrical kindling, and combination of lithium sulphate and pilocarpine ... See full document

... Phenolic compounds are the principal antioxidant constituents of natural products and are composed of phenolic acids and flavonoids, which are potent radical terminators 12 . Many plants exhibit efficient antioxidant ... See full document

... barbiturate induced sleep. Haloperidol, a typical antipsychotic is reported to potentiate barbiturate induced sleep, by decreasing the activity of the nigrostriatal and mesolimbic dopaminergic system ... See full document

... in Haloperidol induced catalepsy in ...received Haloperidol (1 mg/kg), ...neuroprotective effect in antiparkinson’s rat model as it contains numerous antioxidant ... See full document

... Parkinsonism describes a syndrome of Parkinson’s disease (PD) it is a chronic neurodegenerative disorder characterized by the progressive loss of dopaminergic neurons of substantia nigra pars compacta in the ventral ... See full document

... brain haloperidol levels after a dose of haloperidol (Zheng et ...a haloperidol-induced move- ment disorder in mice, which resembles that of human Parkinson’s ... See full document

... drugs, catalepsy was induced by the intraperitonial administration of haloperidol at a dose of 1 mg/kg body weight in normal ...of catalepsy was measured every 30 minutes thereafter for a ... See full document

... male mice (25-30 g) were divided into five groups of six in each. The mice were received normal saline (control group), Methotrexate (20 mg/kg), Methotrexate (20 mg/kg) + Thymoquinone (2, 10 and 20 mg/kg) ... See full document

... albino mice 22–25 g of body weight and aged 5– 6 weeks. Mice were obtained from the animal house colony of the National Research Centre (Cairo, Egypt), housed on a 12-h light/dark cycle and allowed free ... See full document