[PDF] Top 20 Efficacy and safety of oral compared with intravenous tranexamic acid in reducing blood loss after primary total knee and hip arthroplasty: a meta analysis
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Efficacy and safety of oral compared with intravenous tranexamic acid in reducing blood loss after primary total knee and hip arthroplasty: a meta analysis
... of total blood loss in total joint arthroplasty [30, ...the blood loss may leading to postoperative hypoxemia, the blood transfusion is ...However, blood ... See full document
7
Comparative effectiveness and safety of tranexamic acid plus diluted epinephrine to control blood loss during total hip arthroplasty: a meta-analysis
... current meta-analysis demonstrated that TXA plus DEP has a beneficial effect on total blood ...less total blood loss by 209.79 ml than TXA alone. Several ... See full document
11
Comparison of the effectiveness and safety of topical versus intravenous tranexamic acid in primary total knee arthroplasty: a meta-analysis of randomized controlled trials
... in primary TKA is today widely accepted, and several studies and meta-analyses have confirmed the efficacy of TXA at decreasing blood loss without increasing complications and costs [9, ... See full document
11
Review Article Topical fibrin sealant versus intravenous tranexamic acid in reducing blood loss during total joint arthroplasty: a systematic review and meta-analysis
... Objective: Intravenous (IV) tranexamic acid (TXA) and topical fibrin sealant (FS) are two common agents that are used to decrease perioperative blood loss during total joint ... See full document
11
The efficacy of tranexamic acid using oral administration in total knee arthroplasty: a systematic review and meta-analysis
... A standard data entry form was designed for the data extraction. Two reviewers independently extracted the available study data. The extracted data included au- thor(s), patients (n), publication date, age, gender, study ... See full document
11
Comparison of oral versus intra articular tranexamic acid in enhanced recovery primary total knee arthroplasty without tourniquet application: a randomized controlled trial
... clinical efficacy and safety of topical TXA administration compared with pla- cebo in TKA have been confirmed in many RCTs with various dosages ...reduce blood loss and transfusion ... See full document
11
The efficacy and safety of combined administration of intravenous and topical tranexamic acid in primary total knee arthroplasty: a meta analysis of randomized controlled trials
... Tranexamic acid (TXA) is a synthetic lysine analog, it can competitively inhibit the activation of plasminogen and plasmin binding protein [7, ...and meta-analysis studies [11, 12] have shown ... See full document
11
Combined use of intravenous and topical versus intravenous tranexamic acid in primary total knee and hip arthroplasty: a meta-analysis of randomised controlled trials
... intraoperative blood loss and transfu- sion ...cluding intravenous, intraarticular, oral and ...mediators after tourniquet release ...the knee joint should result in greater ... See full document
10
The efficacy of intravenous aminocaproic acid in primary total hip and knee arthroplasty: a meta-analysis
... in total blood loss (mean difference (MD) = − ...present meta-analysis indicated that the application of aminocaproic acid in THA or TKA decreases the total blood ... See full document
8
Combined application versus topical and intravenous application of tranexamic acid following primary total hip arthroplasty: a meta analysis
... Tranexamic acid (TXA) is a synthetic amino acid analogue that acts as a competitive inhibitor of plas- minogen and finally interferes with fibrinolysis ...decrease blood loss and reduce ... See full document
10
The efficacy and safety of tranexamic acid in revision total knee arthroplasty: a meta analysis
... Total knee arthroplasty (TKA) is a common surgical method for the treatment of end-stage knee disease, which could effectively relieve knee pain and greatly improve patient quality of ... See full document
6
The efficacy of topical tranexamic acid in total hip arthroplasty: a meta analysis
... Tranexamic acid is a synthetic analog of the amino acid lysine that acts by blocking the lysine binding sites on plasminogen molecules, inhibiting the formation of plasmin ...and ... See full document
7
Intravenous and subsequent long term oral tranexamic acid in enhanced recovery primary total knee arthroplasty without the application of a tourniquet: a randomized placebo controlled trial
... hidden blood loss or subcutaneous capillary ...of tranexamic acid during hospitalization could reduce the incidence of subcutane- ous ecchymosis in patients undergoing arthroplasty, and ... See full document
9
Comparison of intravenous and topical tranexamic acid in total knee arthroplasty
... in primary TKA using a prospect- ive randomized controlled ...similar safety and efficacy for reducing perioperative blood loss in ...for knee pain in the Topical Group ... See full document
5
Original Article The efficacy and safety of oral tranexamic acid for reducing blood loss after total joint arthroplasty: a meta-analysis
... This meta-analysis aimed to illustrate the efficacy and safety of oral tranexamic acid (TXA) for reducing blood lossafter total joint ... See full document
9
Review Article The efficacy and safety of fibrin tissue adhesive to reduce blood transfusion and blood loss following total hip arthroplasty: a meta-analysis
... This meta-analysis aimed to explore the opti- mal hemostasis agent for ...the efficacy and safety of fibrin tissue adhesive was still in debated and no consensus was ...in reducing the ... See full document
12
The efficacy and safety of tranexamic acid for reducing blood loss following simultaneous bilateral total knee arthroplasty: a multicenter retrospective study
... less blood loss than the IV group following primary TKA [19], which was not consistent with our ...much blood loss compared with primary ...less total blood ... See full document
6
Intraarticular use of tranexamic acid reduces blood loss and transfusion rate after primary total knee arthroplasty
... TXA is usually given intravenously but this is contra- indicated in patients with several comorbidities such as a history of thrombosis, myocardial infarction or severe renal dysfunction. Since patients undergoing TKA ... See full document
6
Tranexamic Acid as Prophylactic Therapy for Intra and Post Partum Hemorrhage, Randomized Controlled Trial
... pulse, blood pressure) of the patients 2 hours, 6 hours and 24 hours after ...mg/dl) compared to control group ...(37.63±5.4) compared to control ...of blood lost during cesarean ... See full document
7
Original Article The reduction in blood loss with an intravenous drip of tranexamic acid in decompression and fusion surgery for degenerative lumbar spinal stenosis: a randomized controlled trial
... significant blood loss [1]. Excessive blood loss could result in anemia and coagu- lopathy or more serious ...infection, blood-borne disease transmission, and greater mortality rates ... See full document
6
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