[PDF] Top 20 Embryonic origin of human hematopoiesis

... the origin of the adult hematopoietic ...ephemeral hematopoiesis, characterized by the early appearance of hematopoietic progenitors with limited development ability that rapidly differentiate toward ... See full document

... Therefore, human GATA4-transgenic HUVECs (HUVEC-GATA4) were generated to compare GATA4-mediated gene expression changes in this cell line (Supplemental Figure 6, F–H) with our findings in the fetal liver and with ... See full document

... Murine embryonic hematopoiesis is a dynamic process notable for the sequential emergence of distinct populations of blood cell progenitors ...predominantly embryonic-type globins. By midgestation ... See full document

... As pluripotent cells of the intact early embryo proliferate for only a limited period of time, it was not initially obvious whether pluripotent cell lines could be established without undergoing malignant transformation. ... See full document

... used human bocavirus 1 (HBoV1) to understand the replication mechanism of ...in human embryonic kidney 293 (HEK293) cells, we identified the HBoV1 minimal replication origin at the right-end ... See full document

... Cell lines used in this study Cells Human HeLa SW13 HepG2 293 Monkey CV1 COSi Origin Genital carcinoma Adrenocortical carcinoma Liver carcinoma Embryonic fibroblasts transformed with ade[r] ... See full document

... mouse embryonic stem (ES) cells into hematopoietic cells includes a clonal progeni- tor intermediate, the BL-CFC, that can generate both endothelial and hematopoietic cells(Choi et ...either hematopoiesis ... See full document

... To determine if direct infection of hematopoietic progenitor cells was occurring, resulting in loss of CFA, we performed quantitative PCR amplification using primers specific for viral sequences (34). These studies ... See full document

... Drosophila hematopoiesis add to the value of flies as a model organism to gain insights into blood ...in human blood ...affect embryonic crystal cell ...Drosophila hematopoiesis is likely to ... See full document

... experiment, we discovered an expansion of erythroid progenitors in the CHT of embryos injected with bif1, where BMP signaling was therefore attenuated. We hypothesize that during stress erythropoiesis, two steps are ... See full document

... that human embryonic gastrointestinal tract smooth muscles (HEGITSM) and human embryonic stem gastrointestinal cells (HEGISC) consistently express KIT, CD34, NCAM, PDGFRA and other stem cell ... See full document

... adult hematopoiesis was initiated in extra-embryonic tissues, mainly the yolk sac (Moore and Owen, ...for hematopoiesis by carrying out experiments in which a quail embryo was transferred into chick ... See full document

... of human neural origin (neuroblastoma), have a relatively high mitotic rate, and display relatively enhanced expression of early/mature neural differentiation markers ... See full document

... for human hematopoietic diseases, such as congenital dyserythropoietic anemia, sideroblastic anemia, hepatoerythropoietic porphyria, hemochromatosis, and myelodysplastic syndrome (MDS) ...of embryonic ... See full document

... and human origin (fetal, neonatal and adult fibroblasts, primary hepatocytes, adult neuronal stem cells, menstrual blood stromal cell, prostate, bladder and ureter cells) can reprogram cells into iPSCs, ... See full document

... between human ‘ES’ cells and EpiSCs suggests that during the derivation process in humans, the epiblast may advance to the equivalent of the post-implantation ...pluripotent human cell lines are widely used ... See full document

... early hematopoiesis through analy- sis of human embryos and fetus is difficult, both practically and ...endothelial origin of murine HSCs few groups engineered transgenic mice to trace the ECs ... See full document

... AGM hematopoiesis Physical pressure created by blood flow in the vasculature has a profound effect on endothelial cell physiology and gene expression (Lehoux and Tedgui, ...regulating hematopoiesis in the ... See full document

... To investigate whether GATA-1 is, as we anticipated, required for development of any of the lineages in which it is expressed, we disrupted the GATA-1 locus in ES cells by gene targeting. Initially, this was performed in ... See full document

... unclear. Human embryonic stem cells (hESCs) derived from the inner cell mass (ICM) of blastocyst-stage embryos have provided an excellent model system for understanding XCI initiation and ...in human ... See full document