[PDF] Top 20 Evidence that IGF binding protein 5 functions as a growth factor
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Evidence that IGF binding protein 5 functions as a growth factor
... serum IGF-I, suggesting that the effects of IGFBP-5 on bone are not mediated by increasing cir- culating IGF-I ...IGFBP-5 functions as a growth factor and acts in part via ... See full document
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Granulosa cell derived insulin like growth factor (IGF) binding proteins are inhibitory to IGF I hormonal action Evidence derived from the use of a truncated IGF I analogue
... insulin-like growth factor (IGF) binding proteins (BPs) may serve as antigonadotropins at the level of the ...occurring IGF-I analogue characterized as a weak ligand of IGFBPs but not ... See full document
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Association between insulin-like growth factor-binding protein-3 polymorphism -202 A/C and the risk of prostate cancer: a meta-analysis
... statistical evidence in this analysis, including a large sample size that permitted weak associations to be estimated, some limitations of this analysis should be ... See full document
9
Pharmacological disruption of insulin like growth factor 1 binding to IGF binding proteins restores anabolic responses in human osteoarthritic chondrocytes
... of IGF-1, leading to a molar ratio of free to bound IGF-1 of less than 1 ...more IGF-1 should be able to reach its receptors on ...in IGF-1 bioactivity in vitro, Sunic and co-workers showed ... See full document
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Expression of MyoD, insulin like growth factor binding protein, thioredoxin and p27 in secondarily overacting inferior oblique muscles with superior oblique palsy
... The decrease in p27 in the IOOA group, in conjunction with the decrease in thioredoxin, may also be evidence of oxidative stress. Sherr and Roberts [16] reported that downregulation of p27 in a particular ... See full document
6
Association of Insulin-like Growth Factor I and Insulin-like Growth Factor–Binding Protein-3 With Intelligence Quotient Among 8- to 9-Year-Old Children in the Avon Longitudinal Study of Parents and Children
... no evidence that associations with overall IQ differed between boys and ...of IGF-I levels with ...in IGF-I levels: ...parental IGF levels on parents’ own educational attainment and their ... See full document
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Regulation of experimental autoimmune encephalomyelitis with insulin like growth factor (IGF 1) and IGF 1/IGF binding protein 3 complex (IGF 1/IGFBP3)
... that IGF-1 or IGF-1/IGFBP3 was acting at the level of the blood–brain barrier in preventing the early inflammation in ...in IGF-1– treated rats ...for IGF-1 would also support the possibility ... See full document
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Insulin-Like Growth Factor Axis Expression in Dental Pulp Cells Derived From Carious Teeth
... insulin-like growth factor (IGF) axis comprises two polypeptide growth factors (IGF-1 and IGF-2), two cell surface receptors (IGF-1R and IGF-2R), and six high ... See full document
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Cumulative mutagenesis of the basic residues in the 201-218 region of insulin-like growth factor (IGF)-binding protein-5 results in progressive loss of both IGF-I binding and inhibition of IGF-I biological action
... of IGF-I and IGFBP-5 were independent of the substratum upon which the cells had ...of IGF-I, failed to influence cell num- ...of IGF-I when captured on the substratum ...of IGF-I from ... See full document
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Hessel, Esther (2007): Die Rolle von Insulin-Like Growth Factor Binding Protein-2 (IGFBP-2) in der chemisch induzierten Kolonkarzinogenese der Maus. Dissertation, LMU München: Tierärztliche Fakultät
... Die Assays für die TaqMan PCR wurden mit der Online-basierten ProbeFinder Software im Assay Design Center der Universal ProbeLibrary erstellt. Dabei wurden die Sequenzen in den Datenbanken Ensembl, RefSeq und EMBL anhand ... See full document
169
Monitoring serum insulin-like growth factor-I (IGF-I), IGF binding protein-3 (IGFBP-3), IGF-I/IGFBP-3 molar ratio and leptin during growth hormone treatment for disordered growth
... Serum IGF-I was measured by a previously reported in-house radioimmunoassay (RIA) method (Gill et ...and 5´2±7´4%, ...between IGF-I and IGFBP-3, the following molecular massess were used: ... See full document
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Combined sprint and resistance training abrogates age differences in somatotropic hormones
... serum growth hormone (GH), insulin-like growth factor-1 (IGF-1) and insulin-like growth factor-binding protein-3 (IGFBP-3) in re- sponse to a combined sprint and ... See full document
19
Characterization of Compensatory Growth in Hybrid Striped Bass (Morone chrysops X Morone saxatilis): Hormones and Mechanisms
... Compensatory growth (CG) is a period of growth acceleration that exceeds normal rates after animals are alleviated of certain growth-stunting ...a growth-stunting / catabolic condition that, ... See full document
173
Reproductive and metabolic endocrinology in rams selected for high or low plasma IGF 1 concentrations : a thesis presented in partial fulfilment of the requirements for the degree of Master of Animal Science at Massey University
... Insulin-like growth factor-binding proteins control the biological functions of IOFs and may affect cell growth through !OF-independent actions (Yi et ...of IGF availability and ... See full document
130
Expression and clinical significance of IGF-1, IGFBP-3, and IGFBP-7 in serum and lung cancer tissues from patients with non-small cell lung cancer
... insulin-like growth factor 1 (IGF-1), insulin-like growth factor binding protein 3 (IGFBP-3), and insulin-like growth factor bind- ing protein 7 ... See full document
8
A characteristic signature of insulin-like growth factor (IGF) axis expression during osteogenic differentiation of human dental pulp cells (hDPCs): Potential co-ordinated regulation of IGF action
... of IGF [42] and IGF1 was included in these assays (Methods section and see ...nity binding of IGFs ...of growth factors to cell surface ...with 5 di ff erent batches of hDPCs and obtained ... See full document
8
The participation of insulin-like growth factor-binding protein 3 released by astrocytes in the pathology of Alzheimer’s disease
... Protein samples were diluted with sample buffer(125 mM Tris-HCl, 4 % SDS, 2 % 2-mercaptoethanol, 20 % gly- cerol, 0.01 % bromophenol blue, pH6.8) and denatured at 95 °C for 3 min. Equal amounts of samples were ... See full document
14
The matrix metalloproteinase and insulin-like growth factor system in oral cancer – a prospective clinical study
... There are numerous studies indicating an important role of MMP-2, MMP-3, MMP-13, IGF-1, and IGFBP-3 in dif- ferent malignancies. However, to the best of our knowledge, there is no report available on serum status ... See full document
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Targeting insulin-like growth factor axis in hepatocellular carcinoma
... both IGF-1R and insulin ...phosphorylated IGF-1R and its downstream pro- teins, including ERK and p70 s6k were all effectively inhib- ited by OSI-906 (OSI) ...HepG2. IGF-1R and insulin receptor ... See full document
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Combined Use of Growth Hormone and Gonadotropin-releasing Hormone Analogues in Precocious Puberty: Theoretic and Practical Considerations
... and growth velocity was ...serum IGF-I levels varied widely, with the mean being 2 ...the IGF-I levels correlated with growth velocity, bone age, or body mass ...mean growth velocity ... See full document
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