[PDF] Top 20 The type and impact of Evidence Review Group (ERG) exploratory analyses in the NICE Single Technology Appraisal (STA) process

... original ERG exploratory analyses, presented in the ERG reports, appear to have influenced recommendations in a smaller proportion of FADs (47%) than ACDs ...the ERG exploratory ... See full document

... The single technology appraisal (STA) process was specifically designed to appraise a single product for a single ...health technology submits a report, which is ... See full document

... the ERG to meet the NICE reference case ...the impact of SICH following thrombolytic therapy. The evidence used to populate the transition probabilities were considered to be relevant to the ... See full document

... idelalisib STA (ID764) submitted by Gilead to NICE. The ERG considered the use of the study 116 rituximab arm to be inconsistent with the licensed indication for venetoclax because these patients had ... See full document

... its Single Technology Appraisal (STA) process, the National Institute for Health and Care Excellence (NICE) invited the manufacturer of evolocumab (Amgen) to submit ... See full document

... the type of treatment (TNFi, IL-6, others) and is modelled using survival curves fitted to treatment discontinuation data from the Canadian observational database ...previous NICE technology ... See full document

... The population modelled was the subgroup of patients in the ATLAS-ACS 2-TIMI 51 trial who were biomarker positive and had not experienced a prior stroke or transient ischaemic attack (TIA). The model consisted of a ... See full document

... its single technology appraisal (STA) process, the National Institute for Health and Care Excellence (NICE) invited the manufacturer of vedolizumab (Takeda UK) to submit ... See full document

... for NICE to recommend their use within the NHS in England. The NICE Single Technology Appraisal (STA) process usually covers new single health technologies within a ... See full document

... significant impact. The NICE single technology appraisal (STA) process covers new technologies, within single indications, usually soon after the UK marketing ... See full document

... the single technology appraisal (STA) process, the National Institute for Health and Care Excellence (NICE) invited Janssen to submit evidence on the clinical and ... See full document

... The ERG recognised that the CS included a good-quality systematic review of the efficacy evidence and that the four key RCTs were all good quality and at low risk of ...clinical review found ... See full document

... the Evidence Review Group (ERG) Warwick Evidence was invited to independently review the evidence submitted by the manufacturer of ixazomib, Takeda ... See full document

... trial evidence, and this was used to support the use of a constant HR which was applied over the whole model ...The ERG considered that including data up to 72 weeks was consistent with the company’s ... See full document

... the ERG requested that these be provided by the company where ...The ERG noted that it is generally recommended that at least five studies should be available for a frequentist meta-analysis, whereas the ... See full document

... the Evidence Review Group (ERG) report into the clinical effectiveness and cost-effectiveness of liraglutide in the treatment of type 2 diabetes mellitus, based upon the manufacturer’s ... See full document

... This observational study was conducted between January 2012 and December 2014 in the Qicha district in the rural area of Hainan in the People’s Republic of China. We chose Qicha district because it had a stable Li ... See full document

... by NICE on wide consultation, compared to the less extensive approach by SMC, may simply be a function of size of ...the process, though mainly with NHS staff rather than patients and ... See full document

... this type of structure cannot be used. For further finite-elements analyses it is very important to measure or somehow provide a breaking system’s stiffness characteristics and to use appropriate non-linear ... See full document

... above analyses pooled the data on each intervention followed by indirect comparison of pooled values, we planned to under- take a Bayesian metaregression analysis combining results of all trials for both ... See full document