[PDF] Top 20 Expression of HERV-Fc1, a Human Endogenous Retrovirus, Is Increased in Patients with Active Multiple Sclerosis
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Expression of HERV-Fc1, a Human Endogenous Retrovirus, Is Increased in Patients with Active Multiple Sclerosis
... defined active/nonactive disease. The association may reflect the increased cellular activation observed during active disease periods, which may augment the activation and perhaps replication of ... See full document
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B cells and monocytes from patients with active multiple sclerosis exhibit increased surface expression of both HERV H Env and HERV W Env, accompanied by increased seroreactivity
... of HERV-H env62/H19 (Env H1TM: aa489- 505; Env H3SU: aa 370-386) [22,23] and syncytin 1 (Env W1TM: aa415-431, Env W3SU: aa301-317) [25], respec- ...the HERV-H and HERV-W Envs, while having highly ... See full document
13
HIV-1 Infection Leads to Increased Transcription of Human Endogenous Retrovirus HERV-K (HML-2) Proviruses In Vivo but Not to Increased Virion Production
... HIV-1-infected patients in the absence or presence of antiretroviral therapy (P ⬍ ...of expression was about 2-fold higher than that seen in uninfected controls, although some patients showed levels ... See full document
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Potential molecular mimicry between the human endogenous retrovirus W family envelope proteins and myelin proteins in multiple sclerosis
... are increased in female MS patients compared to male patients, that this increase correlates with disease severity [36], and that the increase may be caused by HERV-W copies in the X ... See full document
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Type W Human Endogenous Retrovirus (HERV-W) Integrations and Their Mobilization by L1 Machinery: Contribution to the Human Transcriptome and Impact on the Host Physiopathology
... 7. HERV-W Expression in MS and Other Autoimmune Diseases Autoimmune diseases comprise a heterogeneous group of complex multifactorial disorders, all sharing the incorrect recognition of healthy cells and/or ... See full document
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Analysis of Human Endogenous Retrovirus Expression in Multiple Sclerosis Plaques
... to multiple different human chromosomal locations specified in Table ...of expression because it had the lowest expression variation among the ...gene expression levels for each of the ... See full document
9
Comprehensive Analysis of Human Endogenous Retrovirus Group HERV-W Locus Transcription in Multiple Sclerosis Brain Lesions by High-Throughput Amplicon Sequencing
... lating expression of HERV-W loci or cellular genes by RNA inter- ference (RNAi) (51, ...of HERV-W and MS, an important result of our study is that the optimized and comprehensive strategy employed ... See full document
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Quantitative analysis of human endogenous retrovirus-K transcripts in postmortem premotor cortex fails to confirm elevated expression of HERV-K RNA in amyotrophic lateral sclerosis
... ALS patients and non-ALS controls were not perfectly matched for age, gender, postmortem delay or RIN values and the differences be- tween the groups were statistically significant for age, gender and ... See full document
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Analysis of transcribed human endogenous retrovirus W env loci clarifies the origin of multiple sclerosis associated retrovirus envsequences
... mapping HERV-W env cDNA sequences (n = 332) from peripheral blood mononuclear cells of patients with MS and healthy controls onto individual genomic HERV-W env elements, we identified seven ... See full document
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Human Endogenous Retrovirus Expression Profiles in Samples from Brains of Patients with Schizophrenia and Bipolar Disorders
... distinct human endogenous retroviruses (HERVs) may play a role in the etiopathogenesis of neuro- psychiatric ...of HERV transcriptional activity in human ...20 HERV families in a total ... See full document
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HERV W polymorphism in chromosome X is associated with multiple sclerosis risk and with differential expression of MSRV
... Background: Multiple Sclerosis (MS) is an autoimmune demyelinating disease that occurs more frequently in women than in ...men. Multiple Sclerosis Associated Retrovirus (MSRV) is a ... See full document
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Expression analysis of the human endogenous retrovirus HERV K in human astrocytic tumors
... and HERV-K splice products could serve as target. Furthermore, HERV- K derived proteins may play a role during the tumorigenic ...the expression and potential function of HERV-K in ... See full document
6
Identification of an Active Reverse Transcriptase Enzyme Encoded by a Human Endogenous HERV-K Retrovirus
... numerous endogenous retroviral elements that are present in the human genome, the abundant HERV-K family is distinct because several members are transcriptionally active and coding for ... See full document
11
Molecular Characterization and Placental Expression of HERV-W, a New Human Endogenous Retrovirus Family
... for HERV-R (ERV-3) ...complex HERV- W family observed at the DNA level could include well-con- served genomic elements (subset) coexpressed in the ... See full document
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HUMAN ENDOGENOUS RETROVIRUS HERV-E λ 4-1 EXPRESSION IN COXAE ARTHROPLASTIC
... activating human endogenic retrovirus HERV-E λ 4-1 as a result of surgery with massive damage of tissue at the example of total replace- ment of coxae with endoprosthesis, and also study its part in ... See full document
5
Human Cytomegalovirus (HCMV) induces Human Endogenous Retrovirus (HERV) transcription
... elements HERV-T, HERV-W, HERV-F and ERV-9, and betaretrovirus-related class II elements HML-2 - 4 and HML-7 - 8, as well as spuma-virus related class III elements of the HERV-L group were ... See full document
7
Human-Specific Integrations of the HERV-K Endogenous Retrovirus Family
... of endogenous retrovirus-like sequences (HERVs) exist in the genomes of humans and other ...the HERV-K group, contains members that encode functional proteins and that have been implicated in the ... See full document
6
Expression of the Human Endogenous Retrovirus HTDV/HERV-K Is Enhanced by Cellular Transcription Factor YY1
... The human endogenous retrovirus HTDV/HERV-K, which resides in moderate copy numbers in the human genome, is expressed in a cell-type-specific manner, predominantly in teratocarcinoma ... See full document
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HERV-K(OLD): Ancestor Sequences of the Human Endogenous Retrovirus Family HERV-K(HML-2)
... of HERV-K homol- ogous sequences in Old World primates, we observed a second mutational event that emerged at the same time in evolution, leading to a shortened gag gene ...of HERV-K(HML-2) homologues ... See full document
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Characterization of the antibody response specific for the human endogenous retrovirus HTDV/HERV-K.
... the human endogenous retrovi- rus HTDV/HERV-K exists in ...Positive human sera clearly label HTDV particles in immunofluorescence and im- munoelectron ...viral HERV-K Gag ...recombinant ... See full document
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