[PDF] Top 20 Expression and Localization of the Epstein-Barr Virus-Encoded Protein Kinase
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Expression and Localization of the Epstein-Barr Virus-Encoded Protein Kinase
... The protein kinase (PK) encoded by the Epstein-Barr Virus (EBV) BGLF4 gene is the only EBV protein ...The expression pattern of EBV PK during the reactivation of ... See full document
7
The signaling pathways of Epstein-Barr virus-encoded latent membrane protein 2A (LMP2A) in latency and cancer
... the expression of which is controlled by ...synthase kinase-3β ...the protein interaction or localization required for LMP2A- mediated cell ... See full document
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Epstein-Barr Virus Protein Kinase BGLF4 Targets the Nucleus through Interaction with Nucleoporins
... subcellular localization, we first detected the BGLF4 expression patterns in chemically induced EBV-positive NA ...other virus protein(s) FIG 1 Schematic summary of the conserved kinase ... See full document
14
An Epstein-Barr Virus Protein Interacts with Notch
... The Epstein-Barr virus (EBV) BamHI A mRNAs were originally identified in cDNA libraries from naso- pharyngeal carcinoma, where they are expressed at high ...RK-BARF0 protein is shown here to ... See full document
12
Epstein-Barr Virus LF2 Protein Regulates Viral Replication by Altering Rta Subcellular Localization
... of SUMO3-modified Rta or Rta mutants in the presence of Flag-LF2. Input lysates (1%) for pull-down assays are shown in the left half of each panel. Western blotting using anti-Flag antibodies revealed bands ... See full document
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Characterization and Intracellular Localization of the Epstein-Barr Virus Protein BFLF2: Interactions with BFRF1 and with the Nuclear Lamina
... BFRF1 protein of Epstein-Barr virus (EBV) is important for efficient primary viral envelopment and egress ...simplex virus and of pseudorabies virus and whose products are known ... See full document
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Protein Array Identification of Substrates of the Epstein-Barr Virus Protein Kinase BGLF4
... empty expression vector or carrying the doxy- cycline regulatory element plus a BGLF4-expressing ...Inducible expression of BGLF4 in the Akata-BGLF4 cells and expression of endogenous EBNA1 are ... See full document
13
Epstein-Barr Virus-Encoded RK-BARF0 Protein Expression
... Cellular localization of ...cellular localization of these proteins was ...(3). Localization of the green fluorescent protein (GFP) fusion proteins (GFP-Flag-RK- BARF0 and GFP-BARF0) and GFP ... See full document
5
Epstein-Barr Virus-Encoded Protein Kinase (BGLF4) Is Involved in Production of Infectious Virus
... BGLF4 expression by ...PK expression during viral lytic ...transient expression of the EBV BZLF1 gene in 293/EBV ⫹ cells (pSG5/BZLF1 is a gift from Shannon Kenney, University of North Carolina at ... See full document
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Latency Type-Dependent Modulation of Epstein-Barr Virus-Encoded Latent Membrane Protein 1 Expression by Type I Interferons in B Cells
... LMP-1 protein expression in Jijoye-M13 cells and in all the BL lines carrying EBNA-2-deleted virus, while LMP-1 mRNA and protein levels did not increase in the other cell lines ... See full document
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Hyperphosphorylation of EBNA2 by Epstein-Barr Virus Protein Kinase Suppresses Transactivation of the LMP1 Promoter
... the virus periodically converts to the cytolytic form of infection, in which the full repertoire of viral genes is ...EBV protein kinase (PK) encoded by the EBV BGLF4 gene is one of the lytic ... See full document
6
SUMO Binding by the Epstein-Barr Virus Protein Kinase BGLF4 Is Crucial for BGLF4 Function
... nuclear localization phenotype, we selected this mutant for functional ...subcellular localization and uncovers a nuclear export signal ...subcellular localization of the WT and SIM mutant BGLF4 ... See full document
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Disruption of Epstein-Barr Virus Latency in the Absence of Phosphorylation of ZEBRA by Protein Kinase C
... induce expression of lytic cycle mRNAs or proteins from the latent EBV genome but maintained its ability to synergize with Rta (15, ...the protein also be- haved like the wild type. However, a ZEBRA ... See full document
10
The Oncogenic Protein Kinase Tpl-2/Cot Contributes to Epstein-Barr Virus-Encoded Latent Infection Membrane Protein 1-Induced NF-κB Signaling Downstream of TRAF2
... LMP1 expression was determined by costaining with ...TRAF2 expression vector, and 24 h later cell smears were air dried and fixed in 4% paraformaldehyde in phosphate-buffered saline (PBS) for 20 min at ... See full document
13
The Epstein-Barr Virus (EBV)-Encoded Protein Kinase, EBV-PK, but Not the Thymidine Kinase (EBV-TK), Is Required for Ganciclovir and Acyclovir Inhibition of Lytic Viral Production
... the virus to respond to either ACV or GCV (in fact, the IC 50 s of both ACV and GCV are slightly lower in cells infected with the TKmut virus than in cells infected with the WT ...viral protein alone ... See full document
9
X-Box-Binding Protein 1 Activates Lytic Epstein-Barr Virus Gene Expression in Combination with Protein Kinase D
... Epstein-Barr virus (EBV) establishes a latent form of infection in memory B cells, while antibody-secreting plasma cells often harbor the lytic form of ...X-box-binding protein 1 (XBP-1), also ... See full document
8
Epstein-Barr virus-encoded microRNAs as regulators in host immune responses
... the expression level of miR-BART1-5p is reflective of NPC progression ...ubiquitin protein ligase (βTrCP) ...decreased expression of BTRC are associated with poor prognosis in NPC ...Their ... See full document
12
The Epstein-Barr Virus SM Protein Induces STAT1 and Interferon-Stimulated Gene Expression
... ISG expression than 1,000 U of ...the protein encoded by ISG56K was shown to interact with translation initiation factor eIF-3 and inhibit translation ...cell protein synthesis and an ... See full document
12
Epstein-Barr virus latent membrane protein 2 associates with and is a substrate for mitogen-activated protein kinase.
... mutant virus) were negative for LMP2a expression ...of expression were examined by first immunoprecipitating the LMP2a protein from cell lysates followed by immunoblotting with the an- ... See full document
9
Protein Kinase C-Independent Activation of the Epstein-Barr Virus Lytic Cycle
... proteins encoded by these genes are detectable during latency ...The protein prod- ucts of BRLF1 (Rta) and BZLF1 (ZEBRA) autostimulate their expression and reciprocally activate each other ... See full document
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