[PDF] Top 20 Gamma Interferon Controls Mouse Polyomavirus Infection In Vivo
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Gamma Interferon Controls Mouse Polyomavirus Infection In Vivo
... following infection in the absence or pres- ence of IFN- ␥ ...of infection, but then they exponentially increased during the ensuing 54-h culture period ...of infection, regardless of whether the ... See full document
9
A Single Locus Controls Interferon Gamma-Independent Antiretroviral Neutralizing Antibody Responses
... regard, mouse models of murine retroviruses, such as murine leukemia virus (MuLV), have provided essential insights into the molecular mechanisms underlying antiviral immune ...MuLV infection through a ... See full document
13
Type 1 Interferon Induction of Natural Killer Cell Gamma Interferon Production for Defense during Lymphocytic Choriomeningitis Virus Infection
... in vivo IFN- ␥ induction has been reported in the mouse peritoneum dur- ing different viral infections (31), and intracellular IFN-␥ expres- sion by splenic NK cells has been observed following treatments ... See full document
10
Gamma Interferon Signaling in Oligodendrocytes Is Critical for Protection from Neurotropic Coronavirus Infection
... immunity controls resistance of C57BL/6, but not BALB/c, mice to in- fection with the mouse-adapted human severe acute respira- tory syndrome (SARS) coronavirus (21, ... See full document
5
Proinflammatory Effects of Interferon Gamma in Mouse Adenovirus 1 Myocarditis
... MAV-1 infection, suggesting that IFN-␥ plays a pro- inflammatory role in the heart, as it does in some studies of CVB3 myocarditis (15, ...than controls following ...susceptible mouse strains ... See full document
12
Modulation by gamma interferon of antiviral cell-mediated immune responses in vivo.
... against gamma interferon. In comparison with controls, the increase of numbers of CD8 1 T cells and the generation of virus-specific cytotoxic T lymphocytes in spleens and virus clearance from organs ... See full document
6
Human CD46 Enhances Nitric Oxide Production in Mouse Macrophages in Response to Measles Virus Infection in the Presence of Gamma Interferon: Dependence on the CD46 Cytoplasmic Domains
... CD46 was originally identified as a human cell receptor for laboratory-adapted MV Edmonston strain and Edmonston- like Halle strain (11, 54). Subsequent studies show that many wild-type MV strains do not interact with ... See full document
10
Inhibition of Retrograde Transport Limits Polyomavirus Infection In Vivo
... JC polyomavirus (JCPyV) induces progressive multifocal leukoencephalopathy, a severe demyelinating disease in multiple sclerosis patients receiving immunomodulatory therapy, and BK polyomavirus ... See full document
12
Interferon Alpha Subtype-Specific Suppression of HIV-1 Infection In Vivo
... HIV-1 infection, and recapitulate the classic hall- marks of human HIV-1 infection, including persistent infection and CD4 ⫹ T cell depletion (37, ...the mouse equivalent [48]) to demonstrate ... See full document
13
Decreased ex vivo production of interferon gamma is associated with severity and poor prognosis in patients with lupus
... active infection on the date of the IGRA; (iii) patients with end-stage renal disease; and (iv) patients with absent complement 3 (C3), C4 or anti-double-stranded DNA (dsDNA) results on the date of the ...healthy ... See full document
9
Gamma Interferon Is Dispensable for Neopterin Production In Vivo
... We found that neopterin levels are increased in patients with cIFN- ␥ R1D, cIFN- ␥ R2D, IL-12p40D, and IL-12R  1D. All these patients experienced early and severe mycobacterial in- fections, Salmonella infections, and, ... See full document
5
Gamma Interferon-Induced Interferon Regulatory Factor 1-Dependent Antiviral Response Inhibits Vaccinia Virus Replication in Mouse but Not Human Fibroblasts
... of infection is more efficiently restricted in immunocom- petent mice (31, 76, ...VACV infection in mice and reduces the virus titer in the lungs about 1,000-fold ...of infection and altered disease ... See full document
12
DNA methylation of the interferon-gamma promoter in association with overexpression of the interferon-gamma gene in periodontal disease
... adaptor protein, TNF receptor-associated factor 6, resulting in a strong inhibition of RANKL transcription (Takayanagi et al. 2000). Opposing evidence exists to support a decrease in the amount of trabecular bone and ... See full document
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Mice Lacking Alpha/Beta and Gamma Interferon Receptors Are Susceptible to Junin Virus Infection
... in vivo interferon does not directly ...and gamma interferon receptor-deficient mice (Hybrid/IFN- ␣ / ␥ R ⫺/⫺ ) or wild-type (Hybrid) mice infected with JUNV in comparison with the ... See full document
5
Interferon gamma ELISPOT for the screening and diagnosis of latent tuberculosis infection in healthy population of China
... The interferon gamma release assay (IGRAs) is an ef- fective tool for enumerating the number of cells produc- ing IFN- in response to a whole series of antigens, in- cluding peptides, peptide pools, ... See full document
10
Poxvirus-Encoded Gamma Interferon Binding Protein Dampens the Host Immune Response to Infection
... natural mouse pathogen and the causative agent of mousepox, is closely related to variola virus (VARV), which causes smallpox in ...host gamma interferon (IFN- ␥ ) receptor ...to infection ... See full document
8
Inhibitory Effects of Nitric Oxide and Gamma Interferon on In Vitro and In Vivo Replication of Marek's Disease Virus
... physiological processes (e.g., as a neurotransmitter and vaso- dilator) (3, 37). NO is also recognized as an important factor in nonspecific immunity with microbiocidal activities against a broad spectrum of protozoa, ... See full document
8
The Antiviral Response to Gamma Interferon
... The primary antiviral response to IFN- ␥ is not dependent on an IFN- ␣ /  response. Accepting that IFN-␥ treatment ef- ficiently primes the induction of IFN- and, both directly and indirectly, ISGs and that it can also ... See full document
9
Short-term treatment with gamma interferon induces stable reversion of ras-transformed mouse fibroblasts.
... Clones IFN-4 and IFN-10 were used as recipients for the introduction of the v-mos or v-H-ras oncogene via transfec6307 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest P[r] ... See full document
5
Interferon-gamma release assay for the diagnosis of latent tuberculosis infection: a latent-class analysis
... tuberculosis infection (LTBI) is essential for TB ...and interferon-gamma release assays (IGRAs) for LTBI diagnosis in various patient populations using Bayesian latent class ... See full document
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