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A gene expression ratio-based diagnostic test for bladder cancer

A gene expression ratio-based diagnostic test for bladder cancer

... benign bladder and bladder cancer samples were obtained from the Tumor Bank at Brigham and Women’s ...for bladder cancer and confirmed histologically by the tumor bank ... See full document

6

A preoperative diagnostic test that distinguishes benign from malignant thyroid carcinoma based on gene expression

A preoperative diagnostic test that distinguishes benign from malignant thyroid carcinoma based on gene expression

... thyroid cancer is increasing, with a global esti- mate of one-half million new cases this ...preoperative test for initial thyroid nodule diagnosis ...are diagnostic of papil- lary thyroid carcinoma, ... See full document

10

Diagnostic significance of microRNAs as novel biomarkers for bladder cancer: a meta analysis of ten articles

Diagnostic significance of microRNAs as novel biomarkers for bladder cancer: a meta analysis of ten articles

... miRNAs are a series of short (generally around 22 nucleotide long), single-stranded, and non-protein- coding RNA gene products that are vital for the regula- tion of gene expression. They work ... See full document

10

Urine exosome gene expression of cancer-testis antigens for prediction of bladder carcinoma

Urine exosome gene expression of cancer-testis antigens for prediction of bladder carcinoma

... diagnosis. Based on the differential expression of some CTAs in urological disorders, they might be applied as diagnostic markers in these kinds of ... See full document

9

Biomarkers for Predicting Clinical Outcomes of Chemoradiation-Based Bladder Preservation Therapy for Muscle-Invasive Bladder Cancer

Biomarkers for Predicting Clinical Outcomes of Chemoradiation-Based Bladder Preservation Therapy for Muscle-Invasive Bladder Cancer

... MRE11 expression was significantly associated with better CSS in 179 invasive bladder cancer patients treated with definitive radiotherapy at 55 Gy (hazard ratio [HR] ...MRE11 ... See full document

28

Urinary exosomal expression of long non-coding RNAs as diagnostic marker in bladder cancer

Urinary exosomal expression of long non-coding RNAs as diagnostic marker in bladder cancer

... The expression level of each gene was measured by using the following formula: Efficiency^ cycle threshold (CT) normalizer gene / Efficiency^ CT target gene ...of expression of each ... See full document

9

The diagnostic accuracy of urine-based tests for bladder cancer varies greatly by patient

The diagnostic accuracy of urine-based tests for bladder cancer varies greatly by patient

... clustered/correlated test results that occur due to re- peated testing within subjects, they are different tech- niques and results are interpreted differently ... See full document

9

An online tool for evaluating diagnostic and prognostic gene expression biomarkers in bladder cancer

An online tool for evaluating diagnostic and prognostic gene expression biomarkers in bladder cancer

... of diagnostic and prognostic biomarkers based on gene expression data is a powerful approach for investigating ...many gene expression datasets are available, the comprehensive ... See full document

7

Urine microRNAs as biomarkers for bladder cancer: a diagnostic meta-analysis

Urine microRNAs as biomarkers for bladder cancer: a diagnostic meta-analysis

... The SROC curve, AUC, and DOR values are not the only feasible strategies for clinical diagnosis. The likelihood ratio (LR), including PLR and NLR, has an equative effect on the evaluation of diagnostic ... See full document

8

Gene expression based computer aided diagnostic system for breast cancer: a novel biological filter for biomarker detection

Gene expression based computer aided diagnostic system for breast cancer: a novel biological filter for biomarker detection

... Gene expression profiling of peripheral blood cells has been used for early detection of breast ...differentiate cancer from control cases (Aaroe, et ...the expression of 1,368 genes extracted ... See full document

7

Original Article Expression of miR-182 and Foxo3a in patients with bladder cancer correlate with prognosis

Original Article Expression of miR-182 and Foxo3a in patients with bladder cancer correlate with prognosis

... the expression of miR-182 and Foxo3a mRNA in bladder cancer (r = ...high expression of miR-182 was significantly worse than that of those with low miR- 182 ...low expression of Foxo3a ... See full document

11

C14orf166 is a high risk biomarker for bladder cancer and promotes bladder cancer cell proliferation

C14orf166 is a high risk biomarker for bladder cancer and promotes bladder cancer cell proliferation

... the expression of C14orf166, two C14orf166 siRNAs and their cognate control siR- NAs (Scramble) were synthesized by Guangzhou RiboBio Co (Guangdong, ...fresh bladder tumor tissues and adja- cent ... See full document

10

Original Article Expression of TMEM40 in bladder cancer and its correlation with clinicopathological parameters

Original Article Expression of TMEM40 in bladder cancer and its correlation with clinicopathological parameters

... of bladder cancer has made great ...(the Cancer Genome Atlas, TCGA) revealed a study that contained outlined genome, transcriptome, mutational data and correlated many molecular events with specific ... See full document

8

Use of radiotherapy for bladder cancer: A population based study of evolving referral and practice patterns

Use of radiotherapy for bladder cancer: A population based study of evolving referral and practice patterns

... surgeon. These findings coincide with the “gatekeeper” effect and a recent study investigating barriers and enablers to use of RT. 25 Although the variability among surgeons is greater than ROs, it is notable that ~81% ... See full document

22

The role of oncostatin M receptor gene polymorphisms in bladder cancer

The role of oncostatin M receptor gene polymorphisms in bladder cancer

... Oncostatin M (OSM) is first discovered in1986 by Zar- ling et al. and is a member of interleukin-6 family [11, 12]. As a well-known multifunctional cytokine, OSM has multiple effects and functions, which are important in ... See full document

9

PBRM1 suppresses bladder cancer by cyclin B1 induced cell cycle arrest

PBRM1 suppresses bladder cancer by cyclin B1 induced cell cycle arrest

... This work was supported by the grants from National Natural Science Foundation of China (U1301221, 81472384, 81372729, 81272808, 81172431, 81472381,81372883, 81001052); The Science and Technology Planning Project of ... See full document

13

Original Article Role of two single nucleotide polymorphisms in secreted frizzled related protein 1 and bladder cancer risk

Original Article Role of two single nucleotide polymorphisms in secreted frizzled related protein 1 and bladder cancer risk

... all bladder cancer cases (rs3242: ...(consecutive bladder cancer cases rs3242 ...consecutive bladder cancer cases versus early-onset cases) showed significant difference ...all ... See full document

15

Original Article Epigenetically induced silence of SOX10 promotes tumor proliferation and invasion in bladder cancer

Original Article Epigenetically induced silence of SOX10 promotes tumor proliferation and invasion in bladder cancer

... pic expression of SOX10 dra- matically suppressed the mi- gratory ability of bladder can- cer cells (Figure ...plating cancer cells on inserts coated with Matrigel to test the invasive ... See full document

8

Preoperative neutrophil–lymphocyte ratio and fibrinogen level in patients distinguish between muscle-invasive bladder cancer and non-muscle-invasive bladder cancer

Preoperative neutrophil–lymphocyte ratio and fibrinogen level in patients distinguish between muscle-invasive bladder cancer and non-muscle-invasive bladder cancer

... Methods: We identified 669 patients who underwent surgery at our institution, and evaluated their preoperative NLRs and fibrinogen levels. Patients were divided into two groups, NMIBC (group-I) and MIBC (group-II), ... See full document

6

Fiber-modified adenovirus-mediated suicide gene therapy can efficiently eliminate bladder cancer cells in vitro and in vivo

Fiber-modified adenovirus-mediated suicide gene therapy can efficiently eliminate bladder cancer cells in vitro and in vivo

... suicide gene called HSV- TK, the expression of which was restricted to bladder cancer cells under the control of the bladder-specific UPII ...non-bladder cancer tissues, ... See full document

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