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[PDF] Top 20 Genetic overlap between autism, schizophrenia and bipolar disorder

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Genetic overlap between autism, schizophrenia and bipolar disorder

Genetic overlap between autism, schizophrenia and bipolar disorder

... consistently identified rare and de novo point mutations and large structural variants present in genes encoding interacting synaptic proteins [16]. Such studies have reported co-segregation of putative high-risk alleles ... See full document

7

Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia

Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia

... personality disorder (BOR) is determined by environmental and genetic factors, and characterized by affective instability and impulsivity, diagnostic symptoms also observed in manic phases of bipolar ... See full document

9

Epigenome-Wide Association Study of Tic Disorders

Epigenome-Wide Association Study of Tic Disorders

... (OCD, autism, bipolar disorder, schizophrenia, some forms of mental retardation), some disorders involving cortico- striatal pathways similar to tics (as in the case of Parkin- son’s disease), ... See full document

11

Association Study of Sequence Variants in Voltage-gated Ca2+ Channel Subunit Alpha-1C and Autism Spectrum Disorders

Association Study of Sequence Variants in Voltage-gated Ca2+ Channel Subunit Alpha-1C and Autism Spectrum Disorders

... involvement between ASD patients and those with schizophrenia or bipolar disorder might be reflected in the lack of association between the SNPs and ASD in our study despite the ... See full document

7

How to Orient Yourself in the Wilderness

How to Orient Yourself in the Wilderness

... illnesses: bipolar disorder, autism spectrum disorder, factitious disorder by proxy, phobic disorders, dissociative identity disorder, Alzheimer’s disease, schizophrenia, ... See full document

44

ASD and schizophrenia show distinct developmental profiles in common genetic overlap with population based social communication difficulties

ASD and schizophrenia show distinct developmental profiles in common genetic overlap with population based social communication difficulties

... We are extremely grateful to all the families who took part in this study, the midwives for their help in recruiting them, and the whole ALSPAC team, which includes interviewers, computer and laboratory technicians, ... See full document

9

Following the genes: a framework for animal modeling of psychiatric disorders

Following the genes: a framework for animal modeling of psychiatric disorders

... variants between cases and controls ...for schizophrenia [26,27], two for bipolar disorder [25] and one for schizophrenia and bipolar disorder together [25]; three ... See full document

13

Molecular pathways involved in neuronal cell adhesion and membrane scaffolding contribute to schizophrenia and bipolar disorder susceptibility

Molecular pathways involved in neuronal cell adhesion and membrane scaffolding contribute to schizophrenia and bipolar disorder susceptibility

... to schizophrenia and bipolar disorder may involve a substantial, shared contribution from thousands of common genetic variants each of small ...International Schizophrenia Consortium ... See full document

19

Are genetic risk factors for psychosis also associated with dimension-specific psychotic experiences in adolescence?

Are genetic risk factors for psychosis also associated with dimension-specific psychotic experiences in adolescence?

... the schizophrenia and bipolar disorder PRS are significant predictors of other dimensions of psychotic experiences ...identify genetic associations between ...dimension-specific ... See full document

12

Are genetic risk factors for psychosis also associated with dimension specific psychotic experiences in adolescence?

Are genetic risk factors for psychosis also associated with dimension specific psychotic experiences in adolescence?

... the schizophrenia and bipolar disorder PRS are significant predictors of other dimensions of psychotic experiences ...identify genetic associations between ...dimension-specific ... See full document

13

A Comparison of Autistic Like Traits in the Relatives of Patients with Autism and Schizophrenia Spectrum Disorder

A Comparison of Autistic Like Traits in the Relatives of Patients with Autism and Schizophrenia Spectrum Disorder

... the genetic predisposition in existence of this trait in relatives of these patients ...with autism and schizophrenia spectrum disorders have deficiency in terms of interpersonal relationship ... See full document

6

Is Ankyrin a genetic risk factor for psychiatric phenotypes?

Is Ankyrin a genetic risk factor for psychiatric phenotypes?

... with bipolar dis- order and of 69.1% with schizophrenia (alpha = ...same genetic background, minimizing a distortion regarding genetic ...and bipolar disorder we found no ... See full document

5

Genetic relationship between five psychiatric disorders estimated from genome wide SNPs

Genetic relationship between five psychiatric disorders estimated from genome wide SNPs

... of overlap between ADHD and ASD is unexpected and is not consistent with family and data linkage studies, which indicate that the two disorders share genetic risk factors 5,6,58,59 ...not ... See full document

27

Informing DSM-5: biological boundaries between bipolar I disorder, schizoaffective disorder, and schizophrenia

Informing DSM-5: biological boundaries between bipolar I disorder, schizoaffective disorder, and schizophrenia

... with schizophrenia or schizoaffective ...molecular genetic profiles, neuroanatomy or brain ...differences between these different medications as these are beyond the scope of this ... See full document

7

Meta analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24 32 and a significant overlap with schizophrenia

Meta analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24 32 and a significant overlap with schizophrenia

... contacts. Genetic insult which disrupts the synapse as a model of ASD is not novel [60], with genes encoding members of the SHANK, neurexin and neuroligin families, all well established as risk factors for ... See full document

17

Review of evidence of the overlap between schizophrenia and bipolar disorder

Review of evidence of the overlap between schizophrenia and bipolar disorder

... as schizophrenia (Andreasen, 1997) and mood disorders (Soares and Mann, ...with schizophrenia were widely demonstrated (Andreasen, 1997; Woodward et ...with bipolar or unipolar affective disorders ... See full document

9

Genetic relationships between schizophrenia, bipolar disorder, and schizoaffective disorder.

Genetic relationships between schizophrenia, bipolar disorder, and schizoaffective disorder.

... which schizophrenia is placed above bipolar disorder, so that, for example, a person with one or several manic episodes at one stage of their clinical history and predominantly schizophrenic symptoms ... See full document

42

The many roads to mitochondrial dysfunction in neuroimmune and neuropsychiatric disorders

The many roads to mitochondrial dysfunction in neuroimmune and neuropsychiatric disorders

... relationship between the establishment of chronic sys- temic inflammation and the development of chronic neu- roinflammation is highlighted by numerous authors, the increase in levels of systemic inflammation ... See full document

24

Analysis of Misdiagnosis of Bipolar Disorder in An Outpatient Setting

Analysis of Misdiagnosis of Bipolar Disorder in An Outpatient Setting

... In terms of diagnosis classification, this study showed that there was no significant statistical difference between the two groups. However, the patients of the MD group diagnosed as other specific bipolar ... See full document

9

Predictors and correlates for weight changes in patients co treated with olanzapine and weight mitigating agents; a post hoc analysis

Predictors and correlates for weight changes in patients co treated with olanzapine and weight mitigating agents; a post hoc analysis

... as bipolar disorder or schizophrenia, obesity is a common ...with schizophrenia (42%), [5] the potential risk of weight gain needs to be evaluated ... See full document

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