[PDF] Top 20 Human polyomavirus JC virus genome.
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Human polyomavirus JC virus genome.
... A region of the polyoma virus genome between the replication origin and late protein coding sequences is required in cis for both early gene expression and viral DNA replication.. Nuclei[r] ... See full document
12
Age-Specific Seroprevalence of Merkel Cell Polyomavirus, BK Virus, and JC Virus
... cell polyomavirus (MCPyV) in a baculovirus expression system and devel- oped a virus-like particle (VLP) enzyme-linked immunosorbent assay ...0.007). Virus specificity of MCPyV seroreactivity was ... See full document
7
Genotype profile of human polyomavirus JC excreted in urine of immunocompetent individuals
... After the infection of an individual by an unknown route, the virus persists in the kidneys and possibly other internal organs. In adults with immunodeficiency, JCV can be reactivated in oligodendrocytes and ... See full document
6
A loop mediated isothermal amplification assay for the detection and quantification of JC polyomavirus in cerebrospinal fluid: a diagnostic and clinical management tool and technique for progressive multifocal leukoencephalopathy
... whole genome sequence of JCV Mad-1 strain (pJCV1–4- > pJCV: pJCV) [33] was obtained from the Health Science Research Resources Bank (Osaka, ...complete genome of other polyomaviruses, including the BK ... See full document
11
Merkel Cell Polyomavirus Exhibits Dominant Control of the Tumor Genome and Transcriptome in Virus Associated Merkel Cell Carcinoma
... another human polyomavirus, BK polyomavirus, is able to upregulate APOBEC3B in infections of primary renal tubule epithelial cells and that this is at least partially mediated by large T antigen ex- ... See full document
14
Analysis of JC virus DNA purified directly from human progressive multifocal leukoencephalopathy brains.
... Analysis of the restriction endonuclease cleavage fragments of these two DNAs and the human polyomavirus JC Mad-i DNA revealed only slight differences which mapped in a region of the gen[r] ... See full document
9
A cell-free replication system for human polyomavirus JC DNA.
... FIG. 7. JCV TAg-binding site II is essential for JCV DNA replication. DNA replication was analyzed in U138 glioblastoma cells or in HeLa cell extracts. (A) U138 glioblastoma cells were plated and transfected on the ... See full document
8
5-HT2 Receptors Facilitate JC Polyomavirus Entry
... the virus strains Mad-1/SVE ⌬ , Mad-1/SV196 was de- scribed previously (50, ...Simian virus 40 (SV40) strain 776 was propagated in the African green monkey kidney cell line CV-1 as previously described ... See full document
9
A Novel Human Polyomavirus Closely Related to the African Green Monkey-Derived Lymphotropic Polyomavirus
... 950-bp genome fragment spanning parts of the VP3 and VP1 genes was ...the genome and used in nested long-distance PCR (LD-PCR) (all primer sequences and PCR conditions are shown in Tables S1 and S2 in the ... See full document
5
JC Virus Evolution and Its Association with Human Populations
... persistent human polyomavirus JC (JCV) has an esti- mated seroprevalence of 70 to 90% ...different human population ...the virus is often transmitted from parent to child postnatally ... See full document
6
The DNA damage response promotes polyomavirus JC infection by nucleus to cytoplasm NF kappaB activation
... tumor virus belonging to the polyomavirus family that has a ...DNA genome. Both JCV and Polyomavirus BK (BKV), the causative agent of BKV-associated nephropathy, were discovered in 1971 and ... See full document
10
Circulating human microRNAs are not linked to JC polyomavirus serology or urinary viral load in healthy subjects
... MicroRNAs (miRNAs) are small, non-coding RNAs that play an important role in fine-tuning the expression of specific gene products through translational repres- sion and/or mRNA degradation [15]. Due to the role they play ... See full document
9
Physical and Functional Interaction between the Y-Box Binding Protein YB-1 and Human Polyomavirus JC Virus Large T Antigen
... shown to affect gene expression at both the transcriptional and translational levels. We have previously shown that YB-1 modulates transcription from the promoters of the ubiquitous human polyomavirus ... See full document
12
Viral Oncogenes, Noncoding RNAs, and RNA Splicing in Human Tumor Viruses
... simian virus 40 (SV40), one of the most common latent viruses of rhesus ...infect human has attracted the interest of many investigators in the field of cancer research be- cause of its characteristic tumor ... See full document
26
ERK Is a Critical Regulator of JC Polyomavirus Infection
... the human JC polyomavirus (JCPyV), a virus that resides in the kidney of the majority of the population and can cause the fatal, demyelinating disease progressive multifocal ... See full document
19
Age-Specific Seroprevalences of Merkel Cell Polyomavirus, Human Polyomaviruses 6, 7, and 9, and Trichodysplasia Spinulosa-Associated Polyomavirus
... into virus-like particles (VLPs) when expressed in eukaryotic sys- tems, allowing the development of assays to detect specific anti- bodies and to evaluate the seroprevalence of such ...BK polyomavirus ... See full document
6
Comparison of real time PCR and hemagglutination assay for quantitation of human polyomavirus JC
... Human polyomavirus JC (JCV), the etiological agent of the disease progressive multifocal leukoencephalopathy (PML) affects immunocompromised patients particularly patients with ...primary ... See full document
5
Analysis of Capsid Formation of Human Polyomavirus JC (Tokyo-1 Strain) by a Eukaryotic Expression System: Splicing of Late RNAs, Translation and Nuclear Transport of Major Capsid Protein VP1, and Capsid Assembly
... FIG. 10. Structures and splice sites of late RNAs of JCV and SV40. JCV and SV40 share 70% nucleotide identity and have similarities in organization of the genomic DNA. Structures and splice sites of the late RNAs of the ... See full document
14
Viral miRNAs in plasma and urine divulge JC polyomavirus infection
... this polyomavirus is widely distributed in the human population without any clinical manifestation ...viral genome and is shown to be expressed concurrently with the late mRNA transcript, thereby ... See full document
9
Epigenetic regulation of polyomavirus JC
... in human sera against JCV indicates that exposure to the virus is very common and begins in childhood and con- tinues into middle age [reviewed in ...infection virus persists in a latent state and ... See full document
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