[PDF] Top 20 Influenza in surviving cells : a study in host-virus interaction
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Influenza in surviving cells : a study in host-virus interaction
... Whether influenza viruses are titrated in the allantois of whole eggs or in surviving bits of membra ne on-shell, variation from host to host is always ...In surviving bits the ... See full document
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Microarray analysis of MicroRNA expression in peripheral blood mononuclear cells of critically ill patients with influenza A (H1N1)
... H1N1 influenza virus, which yielded AUC of ...miRNA-mediated host-influenza virus protein interactions, wherein we found that miRNAs are involved in regulating important pathways, such ... See full document
15
Selective Translation of Eukaryotic mRNAs: Functional Molecular Analysis of GRSF-1, a Positive Regulator of Influenza Virus Protein Synthesis
... by influenza virus to preferentially synthesize viral ...a virus recruiting a host cell protein as a positive regulator of viral protein synthesis (11, 30, ...with influenza ... See full document
10
Mesenchymal stem cell-derived extracellular vesicles attenuate influenza virus-induced acute lung injury in a pig model
... (stromal) cells (MSCs) mediate their immunoregulatory and tissue repair functions by secreting paracrine factors, including extracellular vesicles ...MSCs. Influenza viruses cause annual outbreaks of acute ... See full document
13
Mammalian innate resistance to highly pathogenic avian influenza H5N1 virus infection is mediated through reduced proinflammation and infectious virus release
... a virus-induced TNF- ␣ response in human macro- phages ...A549 cells (human alve- olar epithelial cell line), induced by the low-pathogenicity PR8 influenza virus, inhibits type I IFN ... See full document
11
Multi-Omics Studies towards Novel Modulators of Influenza A Virus-Host Interaction
... transcriptomics study using human peripheral blood mononuclear cells (PBMC)-derived macrophages and influenza A/Udorn/1972(H3N2) and A/WSN/1933(H1N1) viruses ...in virus infected cells ... See full document
11
Mammalian Innate Resistance to Highly Pathogenic Avian Influenza H5N1 Virus Infection Is Mediated through Reduced Proinflammation and Infectious Virus Release
... a virus-induced TNF- ␣ response in human macro- phages ...A549 cells (human alve- olar epithelial cell line), induced by the low-pathogenicity PR8 influenza virus, inhibits type I IFN ... See full document
10
Reassortment of NS Segments Modifies Highly Pathogenic Avian Influenza Virus Interaction with Avian Hosts and Host Cells
... All chicken and turkey embryos infected with either FPV wt or FPV NS VN died within the first 24 hpi. Embryo mortality did not differ between viruses at the time points indicated in the text (n ⫽ 5/time ... See full document
10
ACE2 expression, suggesting that influenza viral infection could
... the host response of primary human bronchial epithelial cells after challenged with different virus ...infection. Cells were infected with H1N1 (PR8) or PR8 NS1 mutant virus in which ... See full document
11
Inhibitory activity of selenium nanoparticles functionalized with oseltamivir on H1N1 influenza virus
... this study, OTV surface-modified SeNPs with superior antiviral properties and restriction on drug resistance were ...H1N1 influenza virus to host cells through inhibiting the activity ... See full document
11
Network Guided Discovery of Influenza Virus Replication Host Factors
... Understanding virus-host interactions in the context of the human protein-protein interaction (PPI) network will provide a global perspective into how influenza virus manipulates host ... See full document
14
Generation and Comprehensive Analysis of an Influenza Virus Polymerase Cellular Interaction Network
... retrieved virus-host protein interactions from the literature and added them to the VirHostNet knowledge base ...complex host cell partners by proteomic approaches, even though we don’t know ... See full document
9
Coronaviruses and the human airway: a universal system for virus host interaction studies
... the host immune system as well as identifying antiviral compounds and human vaccine ...human cells of- fering a unique platform to study respiratory viruses in cells representing the primary ... See full document
9
Interdependence of Hemagglutinin Glycosylation and Neuraminidase as Regulators of Influenza Virus Growth: a Study by Reverse Genetics
... and virus release which are cru- cial for establishing a productive infection (for a review, see reference ...different influenza A ...mediates virus binding to sialic acid-containing receptors on ... See full document
8
Cell to Cell Variation in Defective Virus Expression and Effects on Host Responses during Influenza Virus Infection
... complex virus- host interactions have been greatly facilitated by the application of fast-evolving single-cell RNA-seq approaches (reviewed in reference ...Our study, along with several other in ... See full document
19
Host and Strain Specific Regulation of Influenza Virus Polymerase Activity by Interacting Cellular Proteins
... avian influenza A (HPAI) viruses of the H5N1 subtype have recently emerged from avian zoonotic reservoirs to cause fatal human ...HPAI virus RNA-dependent RNA polymerase (PB1, PB2, and PA pro- teins) and ... See full document
10
Inhibition of Avian Influenza A Virus Replication in Human Cells by Host Restriction Factor TUFM Is Correlated with Autophagy
... MDCK cells via CRISPR/Cas9-mediated genome ...MDCK cells (selected for being one of the cell lines approved by the ...MDCK cells were treated with hygromycin at 150 g/ml for 2 days. ... See full document
18
Association of the Influenza Virus RNA Polymerase Subunit PB2 with the Host Chaperonin CCT
... of cells with Hsp90 inhibitors, ...The interaction of the PB2 protein with several members of the chaperone family of proteins suggests that these chaperones might perform nonredundant ...293T cells ... See full document
9
Comparative Virus Replication and Host Innate Responses in Human Cells Infected with Three Prevalent Clades (2.3.4, 2.3.2, and 7) of Highly Pathogenic Avian Influenza H5N1 Viruses
... with virus suspensions (64 HA units in phosphate-buffered saline [PBS]), followed by incubation with a nucleoprotein (NP) antibody to detect attached ...2009 virus, as a control, bound extensively to ... See full document
5
Alveolar Macrophages Are Indispensable for Controlling Influenza Viruses in Lungs of Pigs
... In this study, using pigs, an important natural host for influenza virus, and currently circulating human H1N1 influenza viruses 28, we wanted to examine the in vivo role of alveolar mac[r] ... See full document
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