[PDF] Top 20 Interaction Domains of the UL16 and UL21 Tegument Proteins of Herpes Simplex Virus
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Interaction Domains of the UL16 and UL21 Tegument Proteins of Herpes Simplex Virus
... partner. UL16 was previously identified as a binding partner of UL11 in GST pull-down and coimmunoprecipitation experiments ...two proteins was ...from UL21 (48% cover- age of 535 amino acids), a ... See full document
9
The Interaction between Herpes Simplex Virus 1 Tegument Proteins UL51 and UL14 and Its Role in Virion Morphogenesis
... etch virus (TEV) protease cleavage site (Flag-TEV-myc), was con- structed as ...relevant domains of the recombinant viruses used in this ...2, domains of the UL13 to UL15 and UL50 to UL52 genes; line ... See full document
14
Determination of Interactions between Tegument Proteins of Herpes Simplex Virus Type 1
... the interaction of UL36 and UL37 appears to have a definite structural ...inner tegument adjacent to the ...inner tegument layer ...inner tegument layer ...the interaction, though ... See full document
6
Herpes Simplex Virus Tegument Protein VP22 Contains Overlapping Domains for Cytoplasmic Localization, Microtubule Interaction, and Chromatin Binding
... At the early stages of VP22 expression and prior to assembly of VP22 onto MTs, the protein is predominantly cytoplasmic. Moreover, depolymerization of VP22-induced MT bundled with a high concentration of nocodazole ... See full document
10
Packaging Determinants in the UL11 Tegument Protein of Herpes Simplex Virus Type 1
... the interaction with UL16 (7, 24, ...immunodeficiency virus type 1 (HIV-1) Nef (43) in place of the native motif (mutants ...to UL16 (25) suggests that interactions between these two ... See full document
8
Herpes simplex virus type 1 UL14 tegument protein regulates intracellular compartmentalization of major tegument protein VP16
... insoluble proteins accumulate with cells, but, under nor- mal conditions, aggresome formation is prevented by the activity of the cellular protein quality control (PQC) machinery, which consists of molecular ... See full document
13
Analysis of the Interaction between the Essential Herpes Simplex Virus 1 Tegument Proteins VP16 and VP1/2
... the interaction between VP16 and VP1/2 during infection, cells were infected with the HSV-VP16(K343A) mutants and their re- spective wt ...VP16(K343A) virus or the K⌬UL36 virus that contains a large ... See full document
11
Sequential Localization of Two Herpes Simplex Virus Tegument Proteins to Punctate Nuclear Dots Adjacent to ICP0 Domains
... The tegument protein-containing nuclear domains are lo- cated adjacent to the ICP0-containing ...the tegument protein-containing nuclear domains with those formed by immediate-early protein ... See full document
9
Novel Structure and Unexpected RNA-Binding Ability of the C-Terminal Domain of Herpes Simplex Virus 1 Tegument Protein UL21
... in UL21 in the avirulent, spread-deficient PRV strain Bartha ...and domains of ...(B) UL21 is proteolytically cleaved during purification by contaminating ... See full document
13
Nuclear Localization and Shuttling of Herpes Simplex Virus Tegument Protein VP13/14
... The herpes simplex virus type 1 gene UL47 encodes the tegument proteins referred to collectively as VP13/14, which are believed to be differentially modified forms of the same ...of ... See full document
9
A Network of Protein Interactions around the Herpes Simplex Virus Tegument Protein VP22
... any interaction that impinges on the recruitment of VP22 to the virus particle will indirectly affect ICP0 ...a virus lacking both gE and gM in combination packages greatly reduced levels of both ... See full document
12
Intracellular Trafficking of the UL11 Tegument Protein of Herpes Simplex Virus Type 1
... HSV-1 proteins, the UL11 protein localizes to the Golgi apparatus, and previous deletion analyses have revealed that the membrane-trafficking information is contained within the first 49 amino ...functional ... See full document
11
Fluorescent Tagging of Herpes Simplex Virus Tegument Protein VP13/14 in Virus Infection
... capsid proteins, and thus they have been desig- nated sites of capsid assembly ...the virus particle at these ...punctate domains localized around the outside of the nucleus, and these are gradually ... See full document
9
Deletion of UL21 Causes a Delay in the Early Stages of the Herpes Simplex Virus 1 Replication Cycle
... erpes simplex virus 1 (HSV-1) virions, like those of all her- pesviruses, contain a proteinaceous layer, termed the tegu- ment, located between the nucleocapsid and viral ...HSV-1 tegument is ... See full document
5
The Pattern of Tegument-Capsid Interaction in the Herpes Simplex Virus Type 1 Virion Is Not Influenced by the Small Hexon-Associated Protein VP26
... The tegument proteins involved in these interactions have not yet been positively identified for HSV-1, HCMV, or ...two proteins has a counterpart in HSV-1 ...penton-associated tegument ... See full document
5
Interaction and Interdependent Packaging of Tegument Protein UL11 and Glycoprotein E of Herpes Simplex Virus
... UL11-gE interaction facilitates mutual packaging is not clear; however, some clues may be extrapolated from the present study and work done in the ...two proteins likely reflects a block in trafficking or ... See full document
10
Complex Formation between the UL16 and UL21 Tegument Proteins of Pseudorabies Virus
... the UL16 and UL21 ...The UL16 open reading frame is located in a conserved gene cluster within the intron of the spliced UL15 gene adjacent to the conserved UL17 open reading frame in all mammalian ... See full document
13
Domain Interaction Studies of Herpes Simplex Virus 1 Tegument Protein UL16 Reveal Its Interaction with Mitochondria
... 9 UL16-mitochondrion interactions in HSV-1-infected ...of UL16-tagged ...wild-type virus. (C) Localization of UL16-GFP in live-cell recordings of ...of UL16-GFP puncta and nuclear rim ... See full document
23
Dynamic Interactions of the UL16 Tegument Protein with the Capsid of Herpes Simplex Virus
... capsid proteins VP5 and VP22a, raising the pos- sibility that UL16 is added to capsids in the ...of UL16 during the course of an infection, a transfection-infection assay was ...expresses ... See full document
9
Direct and Specific Binding of the UL16 Tegument Protein of Herpes Simplex Virus to the Cytoplasmic Tail of Glycoprotein E
... the UL16-gE interaction is likely to participate is cell-to-cell ...of UL16 in the presence or absence of gE. (A) Vero cells expressing UL16-GFP or deletion mutant UL16(1-155)- GFP, ... See full document
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