[PDF] Top 20 Should lung biopsies be performed in patients with severe asthma?
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Should lung biopsies be performed in patients with severe asthma?
... peripheral lung tissue in patients with “ severe asthma ” The histopathology of asthma was first described from autopsy studies of individuals dying of ...to asthma, including ... See full document
15
Longitudinal trends in clinical characteristics and lung function of patients with severe asthma under treatment in Brazil
... we performed 545 screening, after audit of records we stayed on 306 eligible ...was performed with 234 subjects and the inclusion and exclusion of participants was demonstrated on the flow diagram depicted ... See full document
9
Severe, eosinophilic asthma in primary care in Canada: a longitudinal study of the clinical burden and economic impact based on linked electronic medical record data
... that patients with severe asthma receiving high-dosage ICS/LABA regularly visit primary care clinics in Ontario and use health care ...These patients required more than the average number of ... See full document
9
Update on severe asthma: what we know and what we need
... in severe asthma [63], it is felt that anti-LTs would be beneficial in these ...in patients with severe asthma without definite evidence of benefit: studies have shown either ... See full document
8
Prevalence of specific immunoglobulin E and G against Aspergillus fumigatus in patients with asthma
... consecutive patients with moderate to severe asthma referring to Masih Daneshvari hospital Tehran, Iran, from January 2016 to February ...was performed in all subjects with Aspergillus ...all ... See full document
5
<p>Severe uncontrolled asthma with bronchiectasis: a pilot study of an emerging phenotype that responds to mepolizumab</p>
... Background: Asthma and bronchiectasis are different conditions that frequently ...with severe asthma ...of severe uncontrolled asthmatics with bronchiectasis not related to other ... See full document
8
Refractory Asthma Treatment Is Complicated by Tracheobronchomalacia: Case Reports and Review of the Literature
... [11]. Patients with TBM presented with wheezing, 51%, and wheezing with dyspnea, ...refractory asthma. Of 80 patients with suspected or proven TBM, 40% were found to have COPD and 24% asthma ... See full document
5
<p>Evaluation of the Characteristics of Asthma in Severe and Extremely Severe COPD</p>
... (2) patients underwent bronchodilator reversibility (BDR), blood, and FeNO tests without receiv- ing treatment of any oral or inhaled corticosteroid and bronchodilator therapy within 72 h; and (3) nonsmokers or ... See full document
9
Efficacy and safety of ipratropium bromide/albuterol compared with albuterol in patients with moderate-to-severe asthma: a randomized controlled trial
... overall asthma control did not significantly differ between the CVT-MDI and ALB- HFA groups in this short-term, crossover ...in lung function, no differences in rescue medication use were observed be- tween ... See full document
15
Lung Volume Reduction Surgery for Respiratory Failure in Infants With Bronchopulmonary Dysplasia
... be performed in patients with severe emphysematous ...pediatric patients has not yet been ...with severe bronchopulmonary dysplasia, pulmonary hypertension, and ...right lung was ... See full document
6
Personalised medicine in asthma: from curative to preventive medicine
... with severe asthma managed in secondary ...of asthma onset. For mild-to-moderate asthma managed in primary care, these authors demonstrated three asthma subtypes: early-onset atopic ... See full document
14
Differential expression of CCR2 and CX3CR1 on CD16+ monocyte subsets is associated with asthma severity
... asthmatic patients (n = 22), moderate asthmatic patients (n = 32) and severe asthmatic patients (n = 22) compared to healthy control patients (n = ...and severe asthmatic ... See full document
11
Epigenetics and Chromatin Remodeling Play a Role in Lung Disease
... in lung macrophages, biopsy specimens, and blood cells from patients with severe asthma and smoking asthmatics, as well as in patients with chronic obstructive pulmonary disease ... See full document
10
Severe eosinophilic asthma: from the pathogenic role of interleukin-5 to the therapeutic action of mepolizumab
... for severe eosinophilic asthma, by both the US Food and Drug Administration (FDA) and the European Medicines Agency ...for Asthma guidelines, as an add-on therapy for severe uncontrolled ...in ... See full document
8
Evidence for similarity in symptoms and mechanism: The extra‐pulmonary symptoms of severe asthma and the polysymptomatic presentation of fibromyalgia
... the lung, then it is plausible that evidence based interventions for FMS will have a beneficial effect in asthma, but only for those patients with high levels of extra-pulmonary ...for severe ... See full document
31
Severe refractory asthma: an update
... eosinophilic asthma [74–76, 88], no effect was observed on lung function or airway ...on lung function in the subgroups of adults with severe asthma with o12% reversibility in baseline ... See full document
9
Profile of ciclesonide for the maintenance treatment of asthma
... the lung, high protein binding, and extensive first-pass metabolism, favor higher thera- peutic eff icacy and limited systemic ...improves lung function, asthma symptoms, and rescue inhaler use, ... See full document
8
Original Article The prevalence of gastro-esophageal reflux in asthmatic children
... bronchial asthma is one of ...or severe persistent asthma and to evaluate the clinical response of asthma to anti-reflux ...to asthma and those related to GERD throughout the ... See full document
10
An audit of benign biopsies performed in patients assessed by the Leeds/Wakefield Breast Screening Unit
... Does the detection and proper treatment of ductal carcinoma in situ (DCIS) contribute to mortality reduction? In other words, does the detection of DCIS prevent the development of metastatic invasive cancer and thereby ... See full document
22
BRONCHIAL ASTHMA: AN UNMET DISEASE
... Airway Remodeling: Inflammation results into a number of structural changes in airways including the thickening of basement membrane, subepithelial fibrosis, metaplasia of goblet cells, neovascularization and increased ... See full document
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