[PDF] Top 20 /M cell cycle arrest in the broiler’s kidney
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/M cell cycle arrest in the broiler’s kidney
... and cell cycle in the ...induced cell cycle arrest. The commercial broilers’ growth cycle is about 42 days, and then they will be put into use for ...the cell cycle ... See full document
14
Targeting DTL induces cell cycle arrest and senescence and suppresses cell growth and colony formation through TPX2 inhibition in human hepatocellular carcinoma cells
... the cell cycle by using an imaging flow cytometry ...cancer cell lines (the number of counted photos and cell numbers are indicated under the x axis of the ...the cell nucleus (DaPi ... See full document
16
CMPD1 inhibited human gastric cancer cell proliferation by inducing apoptosis and G2/M cell cycle arrest
... inhibit cell growth and remarkably induce cell apoptosis with expression alternations in apoptotic-related proteins such as Bcl-2, Bax and cytochrome c ...dose-dependent cell cycle ... See full document
9
Lobaplatin arrests cell cycle progression in human hepatocellular carcinoma cells
... HCC cell lines and the underlying molecular mechanisms in terms of cell cycle kinetics were ...HCC cell lines was examined using MTT cell proliferation assay. Cell cycle ... See full document
7
Comparison of Cell Cycle Arrest, Transactivation, and Apoptosis Induced by the Simian Immunodeficiency Virus SIVagm and Human Immunodeficiency Virus Type 1 vpr Genes
... The vpr gene from human immunodeficiency virus type 1 (HIV-1) encodes a 96-amino-acid protein with multiple func- tions in the viral life cycle. The first reported role for vpr was a moderate transactivation ... See full document
11
Downregulation of A20 increases the cytotoxicity of IFN-γ in hepatocellular carcinoma cells
... Abstract: Hepatocellular carcinoma (HCC) is a highly fatal disease mandating development of novel, effective therapeutic strategy. Interferon-gamma (IFN-γ) is a pleiotropic cytokine with immunomodulatory, antiviral, and ... See full document
10
ROSMARINIC ACID ENHANCES CISPLATIN CYTOTOXICITY IN HEPG2 CELL LINE AND ATTENUATES ITS NEPHROTOXICITY IN MICE
... cis addition significantly enhanced cis cytotoxic activity in HepG2 cells. Moreover, Pre-treatment with RA significantly mitigated cis-induced elevation of blood urea nitrogen (BUN) and serum creatinine levels. The ... See full document
13
The role of p21 in regulating mammalian regeneration
... of cell cycle regulation comparing healer MRL to non- healer B6 cells showed that the healer cells had an unusual accumulation of cells in G2/M ...potential arrest was a DNA damage response ... See full document
7
High expression of Ras-related protein 1A promotes an aggressive phenotype in colorectal cancer via PTEN/FOXO3/CCND1 pathway
... To validate whether FOXO3 is a crucial functional down- stream of RAP1A, we constructed the specific plasmid to overexpress FOXO3 expression in CRC cells. The qRT-PCR and western blot indicated FOXO3 expression was ... See full document
15
G2/M Cell Cycle Arrest Correlates with Primate Lentiviral Vpr Interaction with the SLX4 Complex
... sion at the level of translation (6, 29), this is not reflected in the replicative capacity of Vpr-defective viruses in activated CD4-pos- itive (CD4 ⫹ ) T cells. In contrast, Vpr-dependent growth pheno- types have been ... See full document
11
Cell Cycle Arrest in G2/M Promotes Early Steps of Infection by Human Immunodeficiency Virus
... the cell cycle increased transduction by concentrating viral replication complexes in nondividing ...idea, cell division would dilute early viral intermediates prior to integration, so that after ... See full document
10
Numb contributes to renal fibrosis by promoting tubular epithelial cell cycle arrest at G2/M
... G2/M arrest of proximal tubular cells is mediated by ...control. Cell cycle profiles were determined by flow cytometric ...the cell cycle data panels refer to the comparison of ... See full document
16
Reovirus-Induced G2/M Cell Cycle Arrest Requires ς1s and Occurs in the Absence of Apoptosis
... capacity of reovirus strains to inhibit DNA synthesis and in- duce apoptosis are determined by the S1 gene (40, 44). To determine whether apoptosis-associated disruption of cellular DNA is required for reovirus-induced ... See full document
9
Bocavirus Infection Induces Mitochondrion-Mediated Apoptosis and Cell Cycle Arrest at G2/M Phase
... Surprisingly, our studies showed that activation of caspases coincided with the replication of the viral gnome. The effi- ciency of replication correlated well with the level of caspase activation in cells transfected ... See full document
12
Silencing of CXCR4 sensitizes triple-negative breast cancer cells to cisplatin
... cancer cell lines. We found that CXCR4 silencing significantly inhibited cell growth, decreased colony formation, and enhanced cisplatin sensitivity while overexpression of CXCR4 rendered cells more ... See full document
11
Original Article Salidroside induces cell cycle arrest and apoptosis in human cervical cancer SiHa cells
... The cell lysate samples were separated by sodium dodecyl sulfate polyacryl- amide gel electrophoresis (SDS-PAGE) and transferred to polyvinylidene difluoride mem- branes (Millipore, Bedford, MA, ... See full document
9
Perturbation of Cell Cycle Progression and Cellular Gene Expression as a Function of Herpes Simplex Virus ICP0
... the cell cycle arrest which occurs as a consequence of ICP0 expression is p53 ...blast cell line (H1299) with both p53 alleles ...same cell cycle arrest phenotype as ... See full document
11
Cell cycle G2/M arrest through an S phase dependent mechanism by HIV 1 viral protein R
... different cell types (HeLa and CEM-SS), which suggest a general effect of Vpr on these ...show cell cycle-specific effect; while when asynchronized CEM-SS cells were used Vpr may have lit- tle or no ... See full document
18
The new 6q27 tumor suppressor DACT2, frequently silenced by CpG methylation, sensitizes nasopharyngeal cancer cells to paclitaxel and 5-FU toxicity via β-catenin/Cdc25c signaling and G2/M arrest
... The DACT family members are inhibitors of Disheveled, an important Wnt pathway component that suppresses c-Jun N-terminal kinase (JNK) signaling and the β- catenin cascades [27, 28]. DACT2 has been reported to decrease ... See full document
12
Antiproliferative and proapoptotic effects of DODAC/synthetic phosphoethanolamine on hepatocellular carcinoma cells
... as cell cycle and ...of cell cycle, as cyclin A, polo-like kinase 1 (PLK1), cyclin B1, cyclin B2, cyclin-dependent kinase 1 (CDK1), CDC20, cell cycle phosphatases CDC25A and ... See full document
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