[PDF] Top 20 /M cell cycle arrest induced by AFB
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/M cell cycle arrest induced by AFB
... mg/kg AFB 1 ) and AFB 1 group (0.6 mg/kg AFB 1 ...The AFB 1 -contaminated diet was made, similarly to the method described by Kaoud ...mg AFB 1 farinose solid was dissolved into 30 mL ... See full document
15
Reovirus-Induced ς1s-Dependent G2/M Phase Cell Cycle Arrest Is Associated with Inhibition of p34cdc2
... FIG. 3. Cdc2 kinase inhibition following T3A infection results from hyperphosphorylation. L929 cells were either mock infected (M) or infected with T3A (T3) (A) or T1L (T1) (B) at an MOI of 100 PFU per ... See full document
6
Cucurbitacin B inhibits human breast cancer cell proliferation through disruption of microtubule polymerization and nucleophosmin/B23 translocation
... fundamental cell func- tions, including mitotic regulation, maintenance of cell morphology, intracellular motility and macromolecules and organelles trafficking ...regulation, arrest cell ... See full document
12
<p>Procyanidin Compound (PC) Suppresses Lipopolysaccharide-Induced Cervical Cancer Cell Proliferation Through Blocking the TLR4/NF-κB Pathway</p>
... squamous cell carcinoma (TSCC) cells through blocking the secretion of matrix ...tumor cell migration and invasion. In addition, the results of cell cycle distribution ... See full document
13
DNA damage-induced S and G2/M cell cycle arrest requires mTORC2-dependent regulation of Chk1
... damage-induced cell cycle arrest include Chk1, Chk2 and p53 proteins ...etoposide- induced increase in phosphorylation and total protein level of Chk1, and p53 were reduced by ... See full document
14
USP7 is a novel Deubiquitinase sustaining PLK1 protein stability and regulating chromosome alignment in mitosis
... two cell lines, P5091 significantly decreased cell viability in a dose-dependent manner ...decreased cell viability by inducing cell apoptosis and cell cycle ...P5091 ... See full document
12
Glaucocalyxin A induces G2/M cell cycle arrest and apoptosis through the PI3K/Akt pathway in human bladder cancer cells
... GLA was purchased from Shanghai Yuanye Bio-Technology Company (Shanghai, China) and the molecular structure is shown in Fig. 1A. GLA was dissolved in dimethyl sulfoxide (DMSO) and filtered through a 0.22-mm filter ... See full document
9
Sulforaphane inhibits thyroid cancer cell growth and invasiveness through the reactive oxygen species-dependent pathway
... cancer cell proliferation in a dose- and time-dependent manner, induced G2/M phase cell cycle arrest and apoptosis, and inhibited thyroid cancer cell migration and ... See full document
15
<p>Nudol, a phenanthrene derivative from <em>Dendrobium nobile</em>, induces cell cycle arrest and apoptosis and inhibits migration in osteosarcoma cells</p>
... μ M nudol(1) were much higher than the control (Figure ...cantly induced the cleaved forms of cas- pase-3, 8, and 9 of U2OS cells at 48 hrs, illustrating the activation of both extrinsic and intrinsic ... See full document
11
Original Article Salidroside induces cell cycle arrest and apoptosis in human cervical cancer SiHa cells
... of cell cycle arrest is associated with triggering cell apoptosis, which is based on the balanced expression of pro-apoptotic and anti-apoptotic factors ...of cell cycle ... See full document
9
Zinc oxide nanoparticles-induced epigenetic change and G2/M arrest are associated with apoptosis in human epidermal keratinocytes
... changes induced by ZnO NPs were detected by a fluorescence ...NPs induced the increased expression of methyltransferase genes G9a and GLP; the expression of both g9a and glP genes was increased at 50 µg/ml, ... See full document
16
A novel chalcone derivative has antitumor activity in melanoma by inducing DNA damage through the upregulation of ROS products
... melanoma cell growth on plates ...causes cell cycle arrest at the G2/M phase ...lj-1-59-induced cell apoptosis (Additional file 1: Fig. S5b) and partly reversed the ... See full document
17
Metformin impairs growth of endometrial cancer cells via cell cycle arrest and concomitant autophagy and apoptosis
... induces cell cycle arrest and modulates cell cycle proteins in Ishikawa endometrial cancer cells To investigate the underlying mechanisms of metformin- induced growth inhibition ... See full document
12
Original Article Knocking down SMC1A inhibits growth and leads to G2/M arrest in human glioma cells
... underlying cell growth inhibi- tion and cell cycle arrest in SMC1A- deficient U251 cells, we examined the expression of the cell cycle asso- ciated gene CCN- B1IP1, a modula- tor ... See full document
8
Flavokawain derivative FLS induced G2/M arrest and apoptosis on breast cancer MCF-7 cell line
... μ M) reduced the cell num- ber of MCF-7 and induced cell shrinkage after 72 hours of ...of cell was also observed (Figure ...normal cell morphology with extended structure and ... See full document
11
Reovirus-Induced G2/M Cell Cycle Arrest Requires ς1s and Occurs in the Absence of Apoptosis
... capacity of reovirus strains to inhibit DNA synthesis and in- duce apoptosis are determined by the S1 gene (40, 44). To determine whether apoptosis-associated disruption of cellular DNA is required for ... See full document
9
Molecular mechanism of apoptosis induction in skin cancer cells by the centipedegrass extract
... for cell survival and ...promoting cell proliferation and inhibiting apoptosis ...regulate cell proliferation, cell cycle progression, and anti-apoptotic pathways ...promote cell ... See full document
9
High expression of Ras-related protein 1A promotes an aggressive phenotype in colorectal cancer via PTEN/FOXO3/CCND1 pathway
... To validate whether FOXO3 is a crucial functional down- stream of RAP1A, we constructed the specific plasmid to overexpress FOXO3 expression in CRC cells. The qRT-PCR and western blot indicated FOXO3 expression was ... See full document
15
The new 6q27 tumor suppressor DACT2, frequently silenced by CpG methylation, sensitizes nasopharyngeal cancer cells to paclitaxel and 5-FU toxicity via β-catenin/Cdc25c signaling and G2/M arrest
... The DACT family members are inhibitors of Disheveled, an important Wnt pathway component that suppresses c-Jun N-terminal kinase (JNK) signaling and the β- catenin cascades [27, 28]. DACT2 has been reported to decrease ... See full document
12
/M cell cycle arrest in the broiler’s kidney
... In order to define how dietary NiCl 2 induced G 2 /M cell cycle arrest in the kidney, we measured G 2 /M phase cell cycle regulatory molecules. The results showed ... See full document
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