[PDF] Top 20 A Mechanism To Explain the Selection of the Hepatitis e Antigen-Negative Mutant during Chronic Hepatitis B Virus Infection
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A Mechanism To Explain the Selection of the Hepatitis e Antigen-Negative Mutant during Chronic Hepatitis B Virus Infection
... of chronic HBV ...infected chronic carriers, cytosolic HBeAg not only may serve as a CTL target but may actually be a more efficient CTL target than intracellular HBcAg in the ...the virus ... See full document
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Core Antigen Expression Is Associated with Hepatic Necroinflammation in e Antigen-Negative Chronic Hepatitis B Patients with Low DNA Loads
... Hepatitis B virus (HBV) is a circular, partially double- stranded DNA virus (10, ...HBV infection often leads to chronic hepatitis when it occurs in the neonatal period or ... See full document
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Hepatitis B virus reactivation sustained by a hepatitis B virus surface antigen immune escape mutant isolate in a patient who was hepatitis B core antibody positive during treatment with sofosbuvir and velpatasvir for hepatitis C virus infection: a case report
... Chronic infection with either hepatitis B virus (HBV) or hepatitis C virus (HCV) is responsible for a high morbidity and mortality burden ...HCV infection might be ... See full document
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Viral Adaptation to Host Immune Responses Occurs in Chronic Hepatitis B Virus (HBV) Infection, and Adaptation Is Greatest in HBV e Antigen-Negative Disease
... Our study had several limitations. First, despite the large sample size, our study had limited power to detect HLA- associated viral polymorphisms for rare HLA alleles. Second, although we checked for phylogenetic ... See full document
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Clonal Expansion of Normal-Appearing Human Hepatocytes during Chronic Hepatitis B Virus Infection
... of mutant or epigenetically altered hepatocytes that had lost the ability to support infec- tion and that were not, therefore, targeted by antiviral ...may explain why foci of altered hepatocytes (FAH) and ... See full document
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The risk of perinatal hepatitis B virus transmission: hepatitis B e antigen (HBeAg) prevalence estimates for all world regions
... the virus to others, additional HBeAg positivity indicates high viral repli- cation and infectivity with HBV DNA levels of 10 7 – 10 9 IU/mL ...developing chronic HBV infection: 85% [13] to over 90% ... See full document
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Activation of a heterogeneous hepatitis B (HB) core and e antigen-specific CD4+ T-cell population during seroconversion to anti-HBe and anti-HBs in hepatitis B virus infection.
... of antigen- specific T lymphocytes in the periphery of chronically infected patients might be the result of a redistribution of those cells in the ...of chronic type B hepatitis and HBeAg ... See full document
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Distinct patterns of serum hepatitis B core-related antigen during the natural history of chronic hepatitis B
... of hepatitis B virus [16], in which a new no- menclature is used to describe these four phases, ...HBeAg-positive chronic infection, HBeAg-positive chronic hepatitis, ... See full document
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Hbe-antigen negative chronic hepatitis b: prevalence, viral dna characteristic and clinical profile
... E-negative hepatitis results from mutation in the precore (pc) and basal core promoter (bcp) regions of HBV ...Such infection results in hepatitis having lower DNA levels compared to ... See full document
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Comparison of Three Luminescent Immunoassays for Hepatitis B Virus Surface Antigen Quantification during the Natural History of Chronic Hepatitis B Virus Infection
... CHB infection and were not receiving ...presented hepatitis delta virus, hepatitis C virus, or human immunodeficiency virus ...with hepatitis B e ... See full document
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A336C/A336T/T337C variations in HBV core gene and spontaneous hepatitis B e antigen loss in chronic hepatitis B patients
... genotypes B and C accounted for 52.4% (87/166) and 47.6% (79/166) of chronic hepatitis B patients ...genotype B was thought to be related to spontaneous HBeAg ...titis B carriers ... See full document
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Original Article Beta2-Glycoprotein I in Hepatitis B virus infection patients with hepatocellular carcinoma, chronic hepatitis B and acute hepatitis B
... in hepatitis C virus (HCV) carriers presenting autoimmune markers may be mainly represented by increased IL-2, IL-5 and B-cell activating factor (BAFF) ...similar mechanism with anti- ... See full document
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Characterization of Unusual Escape Variants of Hepatitis B Virus Isolated from a Hepatitis B Surface Antigen-Negative Subject
... FIG. 4. Immunoprecipitation of middle and small surface proteins expressed in cell culture. Expression plasmids driving the synthesis of wild-type (WT) and variant (F3 and F4) M and S proteins by the simian virus ... See full document
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Hepatitis B Virus Infection during Pregnancy: Transmission and Prevention
... HBV vaccine in these infants; three addi- tional doses of vaccine (for a total of four doses) should be administrated beginning when the infant reaches the age of 1 month. Infants of HBsAg-positive mothers may be ... See full document
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Prevalence of antibody to Hepatitis B core antigen and Hepatitis B virus DNA in HBsAg negative healthy blood donors
... donor selection procedures along with the application of community based preventive measures such as integra- tion of HBV vaccination in Expanded Programme on Immunization (EPI) since 1993, increased community ... See full document
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Modulation of hepatitis B infection by intravenous application of an immunoglobulin preparation that contains antibodies to hepatitis B e and core antigens but not to hepatitis B surface antigen.
... 2 0022-538X/84/080420-05$02.00/0 Copyright © 1984, American Society for Microbiology Modulation of Hepatitis B Infection by Intravenous Application of an Immunoglobulin Preparation That [r] ... See full document
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Concurrence of Hepatitis B Surface Antigen and Antibody in Acute and Chronic Hepatitis B Cases
... Concurrence of Hepatitis B Surface Antigen and Antibody in Acute and Chronic Hepatitis B Cases ORIGINAL ARTICLE Concurrence of Hepatitis B Surface Antigen and Antibody in Acute and Chronic Hepatitis B[.] ... See full document
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Acute exacerbations of chronic type B hepatitis are accompanied by increased T cell responses to hepatitis B core and e antigens Implications for hepatitis B e antigen seroconversion
... hepatitis B surface antigen (HBsAg) ...responses during acute exacerbations (P less than ...of chronic hepatitis B and in HBeAg ... See full document
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Correlation of Hepatitis B Virus Surface Antigen Titer with Hepatitis Delta Virus Replication Level and Histological Activity in Chronic Hepatitis D
... Chronic hepatitis delta (CHD) is a serious cause of viral hepatitis throughout the world, with high morbidity and mortality rates ...by hepatitis delta virus ...super infection ... See full document
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Serum apolipoprotein C3 levels are negatively associated with hepatitis B virus DNA in HBeAg-negative chronic hepatitis B patients
... A total of 384 CHB patients and 154 healthy individuals were recruited from Qihu Hospital of Shandong University (Qingdao) between December 2016 and September 2018. There were 288 males and 250 females among 538 individ- ... See full document
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