[PDF] Top 20 Mesenchymal stem cell-based therapy for ischemic stroke

... Ischemic stroke is a major cause of death and disability in the aged population ...after stroke may be a viable alternative to intracranial transplantation, but more work in this area is needed ... See full document

... in cell replacement or trans- plantation for their immunosuppressive and tissue repair ...other cell types, the implantation of allo-MSCs may, therefore, be more reasonable and ... See full document

... patients. Based on our analysis, the overall condition of IS patients significantly improved after MSC therapy, indicated by decreased NIHSS and increased BI, FMA and FIM ...medication therapy) with ... See full document

... as cell priming or genetic manipulation; thus, it is convenient to apply for clinical ...encourages cell-to-cell communication as shown in the spheroid culture ... See full document

... “Mesenchymal Stem Cells and Myocardial Ischemia (MESAMI)” Clinical Trial Registration: NCT01076920 is conducted, which has been reported to produce rather impressive results ...chronic ischemic ... See full document

... In cell transplantation therapy, besides selections of ideal timing and the route of cell transplantation, it has also become important to test gene modification and cell preconditioning for ... See full document

... numerous cell regulatory processes, including osteogenic differentiation and regulation of bone formation ...kinase cell surface receptors (BMP receptors ...in mesenchymal osteoprogenitors and also ... See full document

... hematopoietic stem cell transplantation (HSCT), whose efficacy was recently established by a unique international multi-center, open-label phase III, ASTIS (Autologous Stem cell ... See full document

... of therapy include activity modification, conservative pain management strategies, weight loss, and if necessary, replacement of the affected ...joint. Mesenchymal stem cells (MSCs) are a multipotent ... See full document

... The results of this meta-analysis show that MSC adminis- tration improves the MELD score, ALT and TBiL levels, and PT of patients with liver disease. A single MSC ad- ministration, administration into the hepatic artery, ... See full document

... of cell therapy for structural and functional regeneration of the nervous system in diseases related to the aging brain is well ...best cell type to be used or the best methodology for the homing of ... See full document

... bone cell, and fat ...generally based on a comparison on basis of hematogenic system, where MSCs are placed inside bone core, undergo self-renewal, and form cells transforming to many scar tissue ...a ... See full document

... cord stem cells have surged as an alternative viable approach for treating neurological stroke disease ...animal stroke models ...the ischemic tissue, apoptosis reduction and proliferation of ... See full document

... Since mesenchymal stem cells (MSCs) have effective immune-modulatory fea- tures, inhibit T-lymphocyte proliferation, and have a high regenerative capacity, they can play a vital role in the reconstruction ... See full document

... MSC therapy for liver failure Many previous studies have shown that MSC transplant- ation can improve liver function, inhibit hepatocyte apoptosis, and promote hepatocyte proliferation in ani- mal models of ALF ... See full document

... in stroke pa- ...of therapy, and doses of cells are likely to bridge the knowledge gaps that exist with this therapy for patients with ischemic ... See full document

... MSC therapy, leaving the treat- ment group small in comparison with the control ...after stroke, which was followed by an allocation of patients to the experimental groups on day 7 after ...vivo cell ... See full document

... transformation. There is also a risk of microbial contam- ination during in vitro artificial cell expansion of MSCs. Thus, MSC engraftment requires rigorous bacterial test- ing, as well as control of the time and ... See full document

... antibiotics therapy, the patient developed recurrent bullosis diabeticorum on five separate occasions during a 2-year span from 2005 to ...with ischemic diabetic foot, we used bone marrow mesenchymal ... See full document

... in stem cell tissue engineering has created a lot of excitement in the field of cartilage regen- eration ...biology. Stem cells are progenitor cells which dif- ferentiate into various cell ... See full document