[PDF] Top 20 <p>MLPH Accelerates the Epithelial–Mesenchymal Transition in Prostate Cancer</p>
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<p>MLPH Accelerates the Epithelial–Mesenchymal Transition in Prostate Cancer</p>
... 3 MLPH knockdown decreased proliferation, migration, and invasion of PC cell ...of MLPH on cell proliferation were evaluated via colony formation assay at day 14 in PC3 and LNCaP ... See full document
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<p>Overexpression of shugoshin1 predicts a poor prognosis for prostate cancer and promotes metastasis by affecting epithelial–mesenchymal transition</p>
... Based on the aforementioned previously performed studies, we subsequently asserted the notion that SGO1 may play a role in promoting cancer. However, the relationship between PCa and SGO1 is not fully understood. ... See full document
8
<p>A Six-Epithelial–Mesenchymal Transition Gene Signature May Predict Metastasis of Triple-Negative Breast Cancer</p>
... breast cancer remains ...breast cancer suggesting tumour suppressive ...in prostate cancer, 46 provid- ing a plausible explanation for its inclusion in the 6-EMT gene signature identi fi ed for ... See full document
13
<p>miR-1271 inhibits growth, invasion and epithelial–mesenchymal transition by targeting ZEB1 in ovarian cancer cells</p>
... ZEB1 acted as an oncogene and promoted tumori- genesis in several tumors including oral squamous cell carcinoma, glioma and pancreatic cancer. 28 – 30 In hepatocarcinoma cells, ZEB1 regulated the resistance of Dox ... See full document
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<p>TOP2A Promotes Cell Migration, Invasion and Epithelial–Mesenchymal Transition in Cervical Cancer via Activating the PI3K/AKT Signaling</p>
... in prostate cancer patients closely linked to aggressive disease ...in prostate cancer, which was concluded from a fact of sensitivity to combination-targeted ...cervical cancer, TOP2A ... See full document
8
<p>Nicotine promotes cervical metastasis of oral cancer by regulating peroxiredoxin 1 and epithelial–mesenchymal transition in mice</p>
... decreased Prx1 expression in prostate cancer PC3 cells. To further explore the mechanism of Prx1 in nicotine-induced OSCC, we examined the relationship between Prx1 and Ets1 in OSCC cells. We found that ... See full document
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<p>UBE2O Promotes Progression and Epithelial–Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma</p>
... and prostate cancers, ectopic expression of UBE2T could promote cell proliferation and metastasis by inducing ...the cancer EMT process via the activation of the Smad-dependent signaling pathway, UBE2O may ... See full document
12
<p>12-Lipoxygenase promotes epithelial–mesenchymal transition via the Wnt/β-catenin signaling pathway in gastric cancer cells</p>
... where epithelial cells are converted to mesenchymal cells by losing cellular polarity and cell – cell adhesion and acquiring invasive and migratory abil- ...characterizes epithelial cells and plays a ... See full document
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<p>Metadherin Promotes Malignant Phenotypes And Induces Beta-Catenin Nuclear Translocation And Epithelial–Mesenchymal Transition In Gastric Cancer</p>
... Aberrant activation of the WNT/ β -catenin pathway plays important roles in EMT and metastasis in cancer. 21 β -Catenin is degraded by the proteasome after ubiquitylation when acting as a target of GSK3 β that ... See full document
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<p>Quercetin Inhibits Epithelial-to-Mesenchymal Transition (EMT) Process and Promotes Apoptosis in Prostate Cancer via Downregulating lncRNA MALAT1</p>
... To further explore the mechanism of quercetin treatment on prostate cancer, the expressions of p-AKT, AKT, E-cadherin and N-cadherin were determined by Western blot. PI3K/Akt signaling pathway plays ... See full document
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<p>miR-125a-5p inhibits colorectal cancer cell epithelial–mesenchymal transition, invasion and migration by targeting TAZ</p>
... breast cancer by downregulating ...gastric cancer cells by targeting BRMS1 ...colon cancer cell proliferation and induced apoptosis via targeting BCL2, BCL2L12 and ... See full document
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<p>SOX5 promotes cell invasion and metastasis via activation of Twist-mediated epithelial–mesenchymal transition in gastric cancer</p>
... The human GC cells (MGC803, SGC7901, BGC823, AGS, HGC27, KATO-III and MKN45) and normal gastric epithelial GES-1 cells were purchased from the Type Culture Collection of the Chinese Academy of Sciences (Shanghai, ... See full document
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<p>DPY30 regulates cervical squamous cell carcinoma by mediating epithelial–mesenchymal transition (EMT)</p>
... cervical cancer and adjacent normal tissues were obtained from patients who underwent surgery at the Department of Gynecology of Liaocheng People ’ s Hospital between September 2016 and September ... See full document
9
The role of CD44 in epithelial–mesenchymal transition and cancer development
... gastric cancer tissues found that the positive expression rates of CD44v9 in tumor were higher than those in nontumor ...gastric cancer showed higher CD44v9 in comparison with diffuse-type or poorly ... See full document
10
<p>Numb inhibits cell proliferation, invasion, and epithelial–mesenchymal transition through PAK1/β-catenin signaling pathway in ovarian cancer</p>
... ovarian cancer cell lines, we conducted the MTT assays to measure cell prolif- eration in both SKOV3 and OVCAR3 cell lines with loss- of-function and gain-of-function ...ovarian cancer cell ... See full document
11
<p>Upregulated RACK1 attenuates gastric cancer cell growth and epithelial–mesenchymal transition via suppressing Wnt/β-catenin signaling</p>
... lose epithelial cell characteristics, including E-cadherin expression, intercellular adhesion, and epithe- lial cell polarity; and acquire mesenchymal cell character- istics, including migration and ... See full document
11
<p>CircLMNB1 promotes colorectal cancer by regulating cell proliferation, apoptosis and epithelial-mesenchymal transition</p>
... of cancer cells. 34 The EMT is a process by which epithelial cells are transformed into mesenchymal states, which promotes the metastasis of multifarious tumor ...promote prostate ... See full document
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<p>NR1D2 Accelerates Hepatocellular Carcinoma Progression by Driving the Epithelial-to-Mesenchymal Transition</p>
... alters epithelial cell plasticity, thereby inducing a mesenchymal ...an epithelial marker, and increased N-cadherin and vimentin, both constituting mesenchymal ...lung cancer as ... See full document
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<p>TCTP promotes epithelial–mesenchymal transition in lung adenocarcinoma</p>
... Scratch wound healing assays were performed to assess the migration of cancer cells. Lv-TCTP-GFP, Lv-GFP, and Lv- shTCTP-GFP cells seeded in a 24-well plate were grown into a confluent monolayer. After the cells ... See full document
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<p>INTS8 accelerates the epithelial-to-mesenchymal transition in hepatocellular carcinoma by upregulating the TGF-β signaling pathway</p>
... We purchased commercially available immortalized human hepatocyte (MIHA and THLE3) and liver cancer cell lines (HCCLM3, HepG2, MHCC-97H, and SK-HEP-1) from the American Type Culture Collection (Manassas, VA, USA). ... See full document
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