[PDF] Top 20 Network meta-analysis of treatment regimens for inoperable advanced hepatocellular carcinoma with portal vein invasion

... our network meta-analysis should be considered in the interpretation of the ...of portal vein thrombus, type of tumor, and the primary tumor size, and there were slightly differences ... See full document

... the treatment of HCC patients with PVTT. Therefore, only comparative analysis concerning clinical value of TACE or HAIC in combination with RT versus TACE or HAIC alone for HCC patients with PVTT was ... See full document

... HCC invasion and metastasis and is the bottleneck of promoting prognosis of ...and treatment, there still exist differences of opinion among the Eastern and Western ...and treatment of HCC with PVTT ... See full document

... number, portal vein invasion, and extrahepatic metastasis), laboratory test re- sults (albumin, alanine transaminase, aspartate trans- aminase, and total bilirubin levels; prothrombin time; and ... See full document

... other treatment options such as HAIC with chemoembolization and sorafenib also result in poor median survival times of ...tal vein occlusion can prevent both progression of the right PVTT into the left or ... See full document

... biostatistics analysis, vascular invasion is always one of the most important risk factors of tumor recur- rence either in liver resection or liver transplantation [4, 11, ...into portal venules is ... See full document

... without portal vein thrombosis ...developed treatment-related complications including five ...Multivariate analysis revealed that treatment responders ...of portal vein ... See full document

... HCC not amenable to curative resection, distal metastasis (bone or lung) or portal vein thrombosis (VP3 or VP4), and life expectancy of 12 weeks or more. Patients were excluded under following criteria ... See full document

... A meta-analysis of prospective randomized trials has shown that survival is improved after TACE for unresectable HCC with good liver function preservation ...macroscopic portal vein ... See full document

... cular invasion, and the DCP level might reflect expan- sion of macroscopic hepatic vascular invasion ...for advanced HCC with major PVTT should consist of intensive treatment to recanalize the ... See full document

... Results: Propranolol showed a significant reduction in heart rate and PVD for the pre and post- treatment results after three months of treatment (P<0.001 for both). The dose of Propranolol didn't show ... See full document

... for advanced staged HCC patients, particularly patients with PVTT ...microvascular invasion, whereas our study focused on patients with macroscopic ... See full document

... movement of tumour cells [19]. Our results showed that the levels of these proteins were significantly decreased after silencing KIF18A, and we speculated that KIF18A promotes invasion and metastasis of cancer ... See full document

... According to the linear regression, we estimated that the half-life of decreasing AFP levels that respond to sorafenib is 6.84 days. The interval multiphase liver CT showed a con- tinuing decrease in tumor size and PVT ... See full document

... Cell migration was assayed in a transwell chamber with 24-well, 8.0-mm pore polycarbonate membrance (Corning, USA). The same membranes were precoated with matrigel (BD Biosciences, USA) for cell invasion assay. ... See full document

... association with the dose-limiting cardiotoxicity [37]. As studies reported, liposomal doxorubicin has exhibited diminished the cardiac toxicity in various clinical tests, and the combination of pegylated liposomal ... See full document

... the portal- venous ...after treatment shows the complete devascularization of the ...the portal-venous phase which is, however, not a recurrent ... See full document

... of portal vein (type Vp4: 248 ...of portal vein and bellow (type Vp4) was a contradiction for sur- ...of portal vein (Vp3 type), the 3-year, 5-year sur- vival rates of HCC ... See full document

... for portal vein anastomosis (due to thrombosis); hepatic artery anastomosis required autologous middle colic artery interposition graft (due to stenosis); and Roux-en-Y hepaticoje- junostomy was performed ... See full document

... exacerbate portal hypertension, which may result in liver failure or life-threatening variceal bleeding ...optimum treatment strategy for HCC patients with ... See full document