[PDF] Top 20 Neural tissue engineering using embryonic and induced pluripotent stem cells

... existing cells or if the transplanted cells were contributing to the functional ...ES cells to diff er- entiate specifi cally into striatal spiny neurons for trans- plantation ...ES cells, but ... See full document

... various stem cell research ...how stem cells make ‘ decisions ’ during early development and how stem cells function in the ...included embryonic stem cells (ESCs), ... See full document

... Stem cells have been studied widely as a potential resource for regenerative medicine as they can proliferate for long-term while maintaining differentiation ...of cells and tissues within body. ... See full document

... Human stem cell models (CD34+ hematopoietic progenitors, embryonic stem cells and induced pluripotent stem cells (iPSCs)) are powerful tools for the study of ... See full document

... that cells can naturally be reprogrammed or can be forced to do so, most famously by using one or several transcription ...When induced experimentally, the identity of the chosen transcription ... See full document

... Human pluripotent [embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs)] [4, 5] and multi- potent stem cells from adipose [6, 7], ... See full document

... conclusion, stem cells (both normal and cancerous) are a valuable tool in the drug discovery ...tumorigenic stem cell behavior (Figure ...human embryonic stem cells are limited ... See full document

... used stem cells to develop substitute tissue/organs “ex vivo” with various degree of success, which the ultimate goal is to be trans- planted to replace a damaged organ ...a tissue/an ... See full document

... heal. Induced pluripotent stem cells will likely focus more on disease treatment while embryonic stem cells will concentrate on debilitating injuries and degenerative ... See full document

... multipotent cells that are able to proliferate, self- renew, and differentiate into various somatic cells in vitro, and they have attracted much attention for re- storing tissue function in vivo with ... See full document

... human pluripotent stem cells (hPSCs), including embryonic (hESCs) and induced pluripotent stem cells (hiPSCs), as useful models for trophoblast differentiation; ... See full document

... including pluripotent stem cells (embryonic ES and induced pluripotent iPS stem cells); gonadal stem cells (spermatogonial SSCs, ovarian OSCs ... See full document

... The discovery of hPSC-CMs, including hPSC-CMs and hESC-CMs, has been an attractive in vitro model to study cardiotoxicity. Many researchers have used hiPSC- CMs and hESC-CMs as screening models for pro- arrhythmic ... See full document

... by cells, and the high potential in mechanism of integrin and ...(induced pluripotent stem cells), its connections with the environment and tissues as control ...mechanical ... See full document

... Stem cells, which have the ability to self-renew and mul- tipotently differentiate into several phenotypes, have been regarded critical for groundbreaking therapy in the field of regenerative ...In ... See full document

... the pluripotent nes- tin-positive, keratin (K15)-negative stem cells in the hair follicle of mouse can differentiate into glia, neurons, kera- tinocytes, melanocytes and smooth muscle ...expressing ... See full document

... with tissue grafting is ...osteogenic cells, osteo- inductive growth factors and bone-supporting matrix - but are not readily available in every ...as tissue matching, disease transmission, batch ... See full document

... As discussed earlier, the absence of medical alternatives is essential to justify the development of human organs in animals. However, the issue of organ shortage for the treatment of life-threatening conditions by organ ... See full document

... Age-related macular degeneration (AMD), glaucoma, and diabetic retinopathy are three most common causes of visual impairment and legal blindness in developed countries (3,16,17). One common denominator of this condition ... See full document

... OSE cells smears showed the presence of small (2–5μm), round cells which expressed pluripotent markers SSEA- 4, Oct-4, Nanog, Sox-2, and c-kit [5, 6, ...19]. Using a poly- clonal OCT-4 ... See full document