[PDF] Top 20 New roles for rheumatoid factor
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New roles for rheumatoid factor
... Unequivocal proof that RF paraproteins are structurally related and are the products of a limited set of immunoglobulin V genes required a the generation of multiple different antiidioty[r] ... See full document
6
Roles of B cells in rheumatoid arthritis
... activating FcγRIII completely ablates arthritis development [18]. Connecting these model systems to clinical disease, in vitro blockade of FcγRIIIA on human macrophages was recently shown to prevent the release of tumor ... See full document
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The roles of the classical and alternative nuclear factor kappaB pathways: potential implications for autoimmunity and rheumatoid arthritis
... growth factor-β and IL-6 for their differentiation from naïve T cells, and their maintenance and expansion is controlled by IL-23, a cytokine that is produced by ...growth factor- β is not only required for ... See full document
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T cell immune abnormalities in immune thrombocytopenia
... the roles of the new inducible costimulator signal transduction pathway, the ubiquitin proteasome pathway, and the nuclear factor kappa B signal transduction pathway in the induction of T cell ... See full document
6
The Roles of IgG, IgM Rheumatoid Factor, and their Complexes in the Induction of Polymorphonuclear Leukocyte Chemotactic Factor from Complement
... The addition of a purified IgM RF to the mixture of IgG and complement caused a decrease in the chemotactic index. Incubation of IgG and complement before addition of IgM RF produced no change in the chemotactic index. ... See full document
10
Increased IgG Rheumatoid Factor Positivity in the Asian Rheumatoid Arthritis Patients Irrespective of Ethnicity
... Initial observations in our laboratory implied IgG RF to be common among Malaysian patients with RA. As the Malaysia population consists of three major ethnic groups with different genetic backgrounds, but sharing the ... See full document
9
Current Treatment of Juvenile Rheumatoid Arthritis
... Our knowledge of JRA remains incomplete. An improved understanding of disease cause and patho- genesis could provide insights into the possible rela- tionships among different disease subtypes and may also reveal ... See full document
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Possible rheumatoid arthritis subtypes in terms of rheumatoid factor, depression, diagnostic delay and emotional expression: an exploratory case control study
... A cross-sectional study was conducted to compare: a) the trait EI profiles of RA patients against controls at the level of the 15 trait EI facets, and b) the full trait EI profiles between the RF+ and RF- subgroups. The ... See full document
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Original Article An updated meta-analysis of association of rheumatoid arthritis related interstitial lung disease with anti-cyclic citrullinated peptide antibody or rheumatoid factor
... Study quality was assessed using the New- castle-Ottawa quality assessment scale [28] for eleven case-control studies and one cohort study. This scale is comprised of three parts including nine items, by examining ... See full document
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A combination of autoantibodies to cyclic citrullinated peptide (CCP) and HLA DRB1 locus antigens is strongly associated with future onset of rheumatoid arthritis
... need new strategies, both in research intended to understand factors that determine whether an individual with the presently identified risk factors will develop RA, and in clinical practice, where we may now ... See full document
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Article: Quality control and interest of the determination of anti-CCP antibodies and rheumatoid factor in the diagnosis of rheumatoid arthritis
... (antiperinuclear factor), AKA (antikeratin antibody), anti-fillagrin, anti-CCP (anticyclic citullinated peptide antibody) (Vossenaar and Venrooij, ...develop new classification criteria of RA (in 2010) to ... See full document
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Original Article Roles of claudin-5 and von Willebrand factor in patients with rheumatoid arthritis
... mental models [24]. There have been no previ- ous reports regarding the relationship between RA and claudin-5. However, a recent study indi- cated the importance of epithelial cell-cell and cell-extracellular matrix ... See full document
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A Study of correlation of disease severity by Clinical Assessment, Radiological Assessment and IgG Rheumatoid factor in patients with Rheumatoid Arthritis
... low disease activity depending on the joint decision of the clinician and the patient. After that it was investigated which variables among the many, and in particular which combination of variables discriminated best ... See full document
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Original Article The clinical roles of rheumatoid factor in the treatment of chronic hepatitis C infection
... showed the immunomodulating effects of inter- feron may be related to enhancement of macro- phage, cytotoxic T cell, and natural killer cell activity [17]. More HCV-specific CD4+ and CD8+ T cell responses were noted in ... See full document
7
Clinical correlations with Porphyromonas gingivalis antibody responses in patients with early rheumatoid arthritis
... What does seem to be unique in RA is the association between Pg and anti-CCP antibody responses. Consistent with previous reports [14,15], our early RA patients with Pg antibodies more often had anti-CCP antibody ... See full document
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Rheumatoid Factor is a Marker of Disease Severity in Korean Rheumatoid Arthritis
... (60%), respectively. There was no difference in the use of DMARD between groups. However, more patients were prescribed a combination of DMARD in the seropositive than the seronegative group; 59 patients (92.2%) vs. 32 ... See full document
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The occurrence of cryoproteins in synovial fluid; the association of a complement fixing activity in rheumatoid synovial fluid with cold precipitable protein
... with rheumatoid arthritis, and previously implicated as a possible cause of the low synovial fluid complement levels in these patients behaves as a high solubility ...of rheumatoid synovial fluid ... See full document
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Cellular localization of rheumatoid factor idiotypes
... demonstrate rheumatoid factor in the same cells by fluorescent staining with aggregated gammaglobulin were entirely ...of rheumatoid factor in the serum, despite high percentages of cells ... See full document
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Autoantibodies to posttranslational modifications in rheumatoid arthritis
... physiological roles in cell signaling, apoptosis, ion transport systems, wound healing and blood homeostasis, and also the induction of host defense (respiratory burst), genes, and inlammatory ... See full document
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STUDIES ON THE ISOLATION AND CHARACTERIZATION OF THE “RHEUMATOID FACTOR”
... Isolation from specific precipitates In order to eliminate normal 19S y-globulin from isolated fractions of rheumatoid factor the specific property of this material to precipitate with a[r] ... See full document
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