[PDF] Top 20 Normal pressure hydrocephalus: evaluation of diagnostic and prognostic tests

... Cortical sulci should not be prominent and there should be no focal lesions; 3 Decrease in regional cerebral blood flow compared to a group of normal individuals; 4 Variable rather than [r] ... See full document

... three-step prognostic test protocol was launched ...different prognostic or diagnostic tests used in KUH are presented in Table ...10-m tests is considered as a positive result (Table  ... See full document

... the diagnostic revision rate ...initial evaluation of a suspected NPH patient predicts the absence of sustained improvement at 3 years from VPS placement ... See full document

... Some limitations should be addressed. All patients had been diagnosed with iNPH by a specialized team and had undergone shunt surgery, and the MR imaging investigations used in this study had been used in the clinical ... See full document

... Normal pressure hydrocephalus remains a controversial entity with often ambiguous imaging ...in normal pressure hydrocephalus. Often, clinical tests like CSF-Tap ... See full document

... Diagnosis is based on excluding secondary causes, which include intracerebral haemorrhage, space- occupying lesions, and CNS infections. [1] Patients with iNPH usually score above 0.3 (ventriculomegaly) on the Evans ... See full document

... that normal pressure hydrocephalus can be characterized by decreased axial kurtosis and increased axial diffusivity as well as a decreased axonal water fraction in the cortical spinal ...as ... See full document

... The tests used in these studies are presented in Table 2. Only tests that have been reported in at least two studies are ...displayed. Tests assessing different cognitive domains, and having the best ... See full document

... of education of normative data from general population. Post-hoc analyses with Least Significant Difference (LSD) method were performed for between-group comparisons. Intraclass correlation coefficient was calculated to ... See full document

... for evaluation of possible NPH at base- line, following CSF drainage via spinal catheter and again following placement of a permanent ventriculo-perito- neal shunt using objective, sensitive measures of extrapy- ... See full document

... Neuroimaging plays an important role in the diag- nosis of NPH; CT is a useful tool (6–9), and MR imaging of the dynamics of CSF provides some addi- tional help (10, 11). MR imaging—which can delin- eate changes in ... See full document

... Brain MRE of patients with NPH revealed increased brain tissue stiffness in the cerebrum and the occipital, parietal, and temporal lobes compared with age- and sex-matched healthy controls. Al- though not significant, ... See full document

... in normal pressure ...intracranial pressure scores in the presurgical work-up and clinical score, ventricular volume, and aqueduct area and assessed the patient’s response to ... See full document

... parameters of the CSF were within normal limits. After the completion of the three drainages, the patient showed improvements in her gait disturbances and urinary incontinence. Moreover, no seizures were observed ... See full document

... Adjustable valves not only provide the ability to non- surgically increase valve settings to prevent subdural effusions, but also provide the added benefit of high- pressure drainage when needed to aid in the ... See full document

... MATERIALS AND METHODS: The patients with suspected idiopathic normal pressure hydrocephalus on the basis of the ventriculo- megaly and a triad of symptoms underwent the CSF tap test. CSF volumes were ... See full document

... Phase-contrast CSF velocity imaging was performed to mea- sure the aqueductal CSF stroke volume (i.e., the volume of CSF pulsating back and forth through the aqueduct) over the cardiac cycle (14). A 4-mm-thick section ... See full document

... From the Departments of Neuropsychiatry (Y.M., N.Y., H.O.) and Otolaryngology-Head and Neck Surgery (C.S.), Unit of Translation Medicine, and Department of Human Genetics (S.Y., A.K., H.M., K.-i.Y., S.O.), Nagasaki ... See full document

... Considering this information, the patient was investigated. His hematological and biochemical parameters were normal. Brain imaging showed fluid collection in the region of the right parietal-occipital scalp and ... See full document

... idiopathic normal pressure hydrocephalus (iNPH) have reduced cerebrospinal fluid (CSF) concentrations of amyloid-β (Aβ) and α- and β-cleaved soluble forms of amyloid precursor protein (sAPPα and ... See full document