[PDF] Top 20 Nucleolin Is Required for an Efficient Herpes Simplex Virus Type 1 Infection
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Nucleolin Is Required for an Efficient Herpes Simplex Virus Type 1 Infection
... of infection, like viral DNA replication, virus assembly, and control of intracellular trafficking (for reviews see references 22 and ...protein nucleolin (65). Nucleolin is one of the most ... See full document
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Nucleolin Is Required for Efficient Nuclear Egress of Herpes Simplex Virus Type 1 Nucleocapsids
... Herpes simplex virus type 1 (HSV-1) is an enveloped DNA virus and one of the most common human pathogens, causing a wide variety of diseases such as mucocutaneous ... See full document
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Conserved Residues in the UL24 Protein of Herpes Simplex Virus 1 Are Important for Dispersal of the Nucleolar Protein Nucleolin
... of nucleolin similar to that seen with the UL24-null ...for efficient repli- cation. UL12 is another HSV-1 protein with a nuclease motif and for which nuclease activity has been ...proteins ... See full document
11
Nucleolin Interacts with US11 Protein of Herpes Simplex Virus 1 and Is Involved in Its Trafficking
... of nucleolin prevents HSV-1 infec- tion (6), and the expression of nucleolin is required for nuclear egress of HSV-1 nucleocapsids (32), demonstrating that nucleolin FIG 6 ... See full document
9
Circularization of the Herpes Simplex Virus Type 1 Genome upon Lytic Infection
... Analysis of the structure of HSV-1 replicative intermediates is complicated due to their fragility and large size, the occur- rence of inter- and intramolecular recombination, and the fact that not all infecting ... See full document
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Extracellular vesicles during Herpes Simplex Virus type 1 infection: an inquire
... fragment 1; BGLF5: BamHI G leftward frame 5; BHRF1: BamHI fragment H rightward open reading frame 1; BNLF2a: BamHI-N leftward frame 2a; BZLF1: BamHI Z fragment leftward open reading frame 1; CCR5: ... See full document
12
Dendritic Cells Are Required for Optimal Activation of Natural Killer Functions following Primary Infection with Herpes Simplex Virus Type 1
... Optimal IFN- ␥ production by NK cells is dependent on DCs. In vitro evidence has shown NK cell IFN- ␥ production to be regulated by DCs (18), yet the relevance and magnitude of this phenomenon in vivo has not been ... See full document
12
Herpes simplex virus type 1 gene products required for DNA replication: identification and overexpression.
... These data are consistent with the view that the genes ULS, UL8, UL9, UL42, and ULS2, like the genes encoding ICP8 and polymerase 12, 15, are all delayed-early genes, as expected for our[r] ... See full document
9
Linker Histones Are Mobilized during Infection with Herpes Simplex Virus Type 1
... volume expands to up to twice its original size for approxi- mately the first 10 hours of infection (36, 51). Viral replica- tion compartments form and occupy additional volume dur- ing this expansion, but ... See full document
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CD4+ T Cells Are Required for the Priming of CD8+ T Cells following Infection with Herpes Simplex Virus Type 1
... acute infection with HSV-1 in mice lacking CD4 ⫹ T ...mice. Virus- specific CD8 ⫹ T cells were also reduced in number in CD4- depleted mice and in B6 mice lacking major histocompatibility complex ... See full document
13
Herpes Simplex Virus Type 1 UL34 Gene Product Is Required for Viral Envelopment
... U of RQ1 DNase (Promega) and allowing the reaction to proceed at 37°C for 30 min. The nuclear extract was fractionated by centrifugation on a 10-ml 15 to 45% sucrose gradient made up in PBS at 35,000 rpm for 30 min. ... See full document
13
Identification of herpes simplex virus type 1 genes required for origin-dependent DNA synthesis.
... RESULTS Our standard assay for HSV origin-dependent DNA replication used the following plasmids: pKl-2, encoding the immediate-early protein IE175; pMC122 XbaI-F, which contains dbp, pol[r] ... See full document
9
The cytoplasmic domain of herpes simplex virus type 1 glycoprotein C is required for membrane anchoring.
... 1753 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest The herpes simplex virus type 1 HSV-1 glycoprotein C gC gene was altered so that it encoded a truncated glycoprotei[r] ... See full document
9
Phosphorylation of Transcription Factor Sp1 during Herpes Simplex Virus Type 1 Infection
... To investigate the genetic requirements for the phosphory- lation of Sp1, the modification state of Sp1 was studied as a function of infection with several IE mutants (d120, d109, d106, and 5dl1.2). These viruses ... See full document
7
Herpes Simplex Virus Type 1 Immediate-Early Protein ICP22 Is Required for VICE Domain Formation during Productive Viral Infection
... are required for its effects on VICE domains and ...residues 1 to ...the virus and plasmid analyses implicate the N-terminal 146 residues in ICP22’s effects on VICE domains and ... See full document
11
Prevalence of Herpes Simplex Virus type-1, 2 and Varicella Zoster Virus (VZV) in Eye Infection
... the herpes virus were first documented by Hippocrates ...(6). Herpes viruses cause various ocular diseases which are considered as one of the main causes of eye infection etiology and ... See full document
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Evidence that the herpes simplex virus type 1 uracil DNA glycosylase is required for efficient viral replication and latency in the murine nervous system.
... Assessment of the latent viral DNA burden by quantitative PCR QPCR demonstrated a reduction in the number of copies of the Ung- mutant viral Downloaded from http://jvi.asm.org/ on Novemb[r] ... See full document
10
Elimination of Mitochondrial DNA Is Not Required for Herpes Simplex Virus 1 Replication
... AN1 virus infection (43) and demonstrate that UL98 can restore viral repli- cation to near wild-type levels in the absence of UL12 and ...UL98 virus dem- onstrated a slight delay in viral ... See full document
10
ICP0 Is Not Required for Efficient Stress-Induced Reactivation of Herpes Simplex Virus Type 1 from Cultured Quiescently Infected Neuronal Cells
... and required for herpes simplex virus type 1 (HSV-1) reactivation were identified using neuronally differentiated PC12 cells (ND-PC12 cells) in which quiescent infections ... See full document
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Mechanisms of herpes simplex virus type 1 reactivation.
... latent herpes simplex virus type 1 (HSV-1) infection (6), little is known about the mechanisms by which stress induces ... See full document
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